NO2480658T3 - - Google Patents
Info
- Publication number
- NO2480658T3 NO2480658T3 NO10818190A NO10818190A NO2480658T3 NO 2480658 T3 NO2480658 T3 NO 2480658T3 NO 10818190 A NO10818190 A NO 10818190A NO 10818190 A NO10818190 A NO 10818190A NO 2480658 T3 NO2480658 T3 NO 2480658T3
- Authority
- NO
- Norway
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
- C12N15/8203—Virus mediated transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/517—Plant cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16123—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Water Supply & Treatment (AREA)
- Analytical Chemistry (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24478609P | 2009-09-22 | 2009-09-22 | |
PCT/CA2010/001488 WO2011035422A1 (fr) | 2009-09-22 | 2010-09-21 | Procédé de préparation de vlp dérivées de plantes |
Publications (1)
Publication Number | Publication Date |
---|---|
NO2480658T3 true NO2480658T3 (fr) | 2018-02-03 |
Family
ID=43795254
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO10818190A NO2480658T3 (fr) | 2009-09-22 | 2010-09-21 | |
NO10818191A NO2480560T3 (fr) | 2009-09-22 | 2010-09-21 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO10818191A NO2480560T3 (fr) | 2009-09-22 | 2010-09-21 |
Country Status (27)
Country | Link |
---|---|
US (2) | US11826419B2 (fr) |
EP (3) | EP3354657B1 (fr) |
JP (2) | JP5554414B2 (fr) |
KR (4) | KR20180026562A (fr) |
CN (4) | CN107129973A (fr) |
AR (2) | AR078432A1 (fr) |
AU (2) | AU2010300033B2 (fr) |
BR (2) | BR112012006415B1 (fr) |
CA (2) | CA2772962C (fr) |
DK (3) | DK2480658T3 (fr) |
ES (3) | ES2642631T3 (fr) |
HR (3) | HRP20220478T1 (fr) |
HU (3) | HUE036776T2 (fr) |
IL (4) | IL218393A0 (fr) |
IN (2) | IN2012DN02637A (fr) |
MX (2) | MX2012003373A (fr) |
MY (2) | MY158475A (fr) |
NO (2) | NO2480658T3 (fr) |
NZ (2) | NZ598508A (fr) |
PL (3) | PL2480560T3 (fr) |
PT (3) | PT3354657T (fr) |
RU (2) | RU2567012C2 (fr) |
SG (2) | SG178947A1 (fr) |
SI (3) | SI2480560T1 (fr) |
TR (1) | TR201803560T4 (fr) |
WO (2) | WO2011035423A1 (fr) |
ZA (2) | ZA201202835B (fr) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2615372A1 (fr) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Particules semblables au virus grippal a comprenant de l'hemagglutinine |
EP2238253B1 (fr) | 2007-11-27 | 2012-09-12 | Medicago Inc. | Particules pseudovirales (vlp) de la grippe recombinées produites dans des plantes transgéniques exprimant l'hémagglutinine |
IN2012DN00650A (fr) | 2009-06-24 | 2015-06-12 | Medicago Inc | |
NO2480658T3 (fr) * | 2009-09-22 | 2018-02-03 | ||
TWI526539B (zh) | 2010-12-22 | 2016-03-21 | 苜蓿股份有限公司 | 植物中生產類病毒顆粒(vlp)的方法及以該方法生產之vlp |
TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
WO2012171104A1 (fr) | 2011-06-13 | 2012-12-20 | Medicago Inc. | Production de particules de type virus de la rage dans des plantes |
WO2013044203A2 (fr) | 2011-09-23 | 2013-03-28 | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPTARTMENT OF HEALTH & HUMAN SERVICES | Nouveaux vaccins à base de protéine hémagglutinine de la grippe |
US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
PL2760882T3 (pl) | 2011-09-30 | 2023-09-11 | Medicago Inc. | Zwiększenie wydajności cząsteczek wirusowopodobnych w roślinach |
CN104114696B (zh) * | 2011-12-21 | 2017-05-03 | 阿普斯有限责任公司 | 使用具有对水解酶抗性的衣壳的vlp的方法 |
JP6406655B2 (ja) * | 2012-02-22 | 2018-10-17 | 三菱商事フードテック株式会社 | 植物性食品素材の軟化方法、軟化製剤、軟化した植物性食品素材およびそれを用いた食品 |
CA2864733C (fr) * | 2012-03-22 | 2018-09-18 | Fraunhofer Usa, Inc. | Particules de type virus comprenant une matrice de proteine a partir d'un virus enveloppe de plante et utilisations de celles-ci |
AU2013312971B2 (en) | 2012-09-05 | 2019-04-18 | Medicago Inc. | Picornavirus-like particle production in plants |
US9617297B2 (en) * | 2012-10-11 | 2017-04-11 | The Regents Of The University Of California | Apoplast wash fluid recovery for improved recombinant endoglucanase extraction in tabacco leaves |
CA2907591A1 (fr) * | 2013-03-28 | 2014-10-02 | Medicago Inc. | Production de particules de type viral de la grippe dans des plantes |
WO2015034042A1 (fr) | 2013-09-06 | 2015-03-12 | 三菱化学株式会社 | Procédé de production d'une protéine à l'aide d'une plante |
WO2015054639A1 (fr) | 2013-10-11 | 2015-04-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Vaccins contre le virus d'epstein-barr |
CA2936350C (fr) | 2014-01-10 | 2023-01-31 | Medicago Inc. | Elements activateurs du cpmv |
RU2731295C2 (ru) | 2014-07-11 | 2020-09-01 | Медикаго Инк. | Модификация продуцирования белков в растениях |
US11191727B2 (en) | 2014-12-31 | 2021-12-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Multivalent nanoparticle-based vaccines |
JP2019129705A (ja) * | 2016-03-31 | 2019-08-08 | 日本たばこ産業株式会社 | 植物に物質を導入する方法 |
IL303650B1 (en) | 2016-09-02 | 2024-10-01 | Us Health | Stable group 2 trimers from the stem region of influenza hemagglutinin and their uses |
WO2019104439A1 (fr) | 2017-11-30 | 2019-06-06 | Medicago Inc. | Protéines vp1 de norovirus modifiées et protéines vp1 de norovirus comprenant des vlp |
TW202016308A (zh) | 2018-06-27 | 2020-05-01 | 加拿大商苜蓿股份有限公司 | 流感病毒血球凝集素突變體 |
JP7429684B6 (ja) * | 2018-07-13 | 2024-03-15 | メディカゴ インコーポレイテッド | 改変ノロウイルスvp1タンパク質および改変ノロウイルスvp1タンパク質を含むvlp |
CN109112093B (zh) * | 2018-09-05 | 2021-11-09 | 上海交通大学 | 一种青蒿原生质体高效分离及瞬时转化的方法 |
CA3137447A1 (fr) * | 2019-04-25 | 2020-10-29 | Flagship Pioneering Innovations Vi, Llc | Compositions et procedes se rapportant a des paquets de messagers vegetaux |
CN110483616B (zh) * | 2019-07-31 | 2021-06-04 | 中国农业科学院农产品加工研究所 | 从感染病原菌的植物组织中分离病原菌分泌的质外体效应蛋白的方法 |
CN111060696B (zh) * | 2019-12-27 | 2023-09-08 | 湖南农业大学 | 一种降低植物小分子信号肽假阳性率的方法 |
CN111718394A (zh) * | 2020-06-28 | 2020-09-29 | 广西壮族自治区农业科学院 | 一种基于bpp法的甘蔗组织变性蛋白提取方法 |
CN111826394A (zh) * | 2020-08-07 | 2020-10-27 | 浙江华缔药业集团医药开发有限公司 | 植物瞬时表达载体的构建及应用 |
WO2022260849A1 (fr) | 2021-06-09 | 2022-12-15 | Nant Holdings Ip, Llc | Procédés et systèmes de production d'une protéine d'intérêt dans une plante |
CN114934007B (zh) * | 2022-07-01 | 2023-11-24 | 广东省农业科学院作物研究所 | 一种甘薯原生质体的制备方法 |
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AU6504796A (en) * | 1995-07-20 | 1997-02-18 | Washington State University Research Foundation | Production of secreted foreign polypeptides in plant cell culture |
US5773695A (en) * | 1996-01-26 | 1998-06-30 | North Carolina State University | Plant nuclear scaffold attachment region and method for increasing gene expression in transgenic cells |
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