NO20081292L - Pentasykliske kinaseinhibitorer - Google Patents

Pentasykliske kinaseinhibitorer

Info

Publication number: NO20081292L
Authority: NO; Norway
Prior art keywords: kinase inhibitors; pentacyclic; malignancies; compounds; useful
Prior art date: 2005-08-12

Application number

NO20081292A

Other languages

English (en)

Inventor

Aihe Zhou

Matthias Rueth

Thomas E Rawson

Brian Safina

Jennafer Dotson

Ignacio Aliagas-Martin

Jason Halladay

Jun Liang

Bin-Yan Zhu

Frederick Brookfield

Michael Prime

Birong Zhang

Jun M Li

Original Assignee

Hoffmann La Roche

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-08-12

Filing date

2008-03-11

Publication date

2008-05-13

2008-03-11 Application filed by Hoffmann La Roche, Genentech Inc filed Critical Hoffmann La Roche

2008-05-13 Publication of NO20081292L publication Critical patent/NO20081292L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20081292A 2005-08-12 2008-03-11 Pentasykliske kinaseinhibitorer NO20081292L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US70790205P	2005-08-12	2005-08-12
PCT/US2006/031682 WO2007022102A2 (en)	2005-08-12	2006-08-14	Pentacyclic kinase inhibitors

Publications (1)

Publication Number	Publication Date
NO20081292L true NO20081292L (no)	2008-05-13

Family

ID=37607426

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20081292A NO20081292L (no)	2005-08-12	2008-03-11	Pentasykliske kinaseinhibitorer

Country Status (14)

Country	Link
US (1)	US7749994B2 (no)
EP (1)	EP1919920B1 (no)
JP (1)	JP2009504680A (no)
KR (1)	KR20080035691A (no)
CN (1)	CN101287737A (no)
AT (1)	ATE509933T1 (no)
AU (1)	AU2006279659A1 (no)
BR (1)	BRPI0615141A2 (no)
CA (1)	CA2619276A1 (no)
IL (1)	IL189296A0 (no)
NO (1)	NO20081292L (no)
RU (1)	RU2008108903A (no)
WO (1)	WO2007022102A2 (no)
ZA (1)	ZA200801332B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009089482A1 (en)	2008-01-11	2009-07-16	Albany Molecular Research, Inc.	(1-azinone) -substituted pyridoindoles as mch antagonists
US9073925B2 (en) *	2009-07-01	2015-07-07	Albany Molecular Research, Inc.	Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
WO2011003007A1 (en) *	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
JP2012532144A (ja) *	2009-07-01	2012-12-13	アルバニーモレキュラーリサーチ，インコーポレイテッド	アジノン置換アゼピノ［ｂ］インドールおよびピリド−ピロロ−アゼピンｍｃｈ−１拮抗薬、ならびにその作製方法および使用
WO2011003012A1 (en) *	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof
US8993765B2 (en)	2010-12-21	2015-03-31	Albany Molecular Research, Inc.	Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof
WO2012088038A2 (en)	2010-12-21	2012-06-28	Albany Molecular Research, Inc.	Piperazinone-substituted tetrahydro-carboline mch-1 antagonists, methods of making, and uses thereof
JP6653573B2 (ja)	2012-05-22	2020-02-26	トラスティーズ・オブ・ダートマウス・カレッジ	シクロアルカニル［ｂ］インドール、シクロアルカニル［ｂ］ベンゾフラン、シクロアルカニル［ｂ］ベンゾチオフェンを合成するための方法、化合物および使用の方法
WO2017162661A1 (en)	2016-03-22	2017-09-28	Bayer Pharma Aktiengesellschaft	1h-benzo[de]isoquinoline-1,3(2h)-diones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050032869A1 (en)	2003-07-08	2005-02-10	Pharmacia Italia S.P.A.	Pyrazolyl-indole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
WO2006133885A1 (en) *	2005-06-15	2006-12-21	F. Hoffmann-La Roche Ag	Tricyclic fused indole derivatives and their use as aurora kinase inhibitors

2006
- 2006-08-14 WO PCT/US2006/031682 patent/WO2007022102A2/en active Application Filing
- 2006-08-14 EP EP06813425A patent/EP1919920B1/en active Active
- 2006-08-14 CN CNA200680037951XA patent/CN101287737A/zh active Pending
- 2006-08-14 CA CA002619276A patent/CA2619276A1/en not_active Abandoned
- 2006-08-14 KR KR1020087005941A patent/KR20080035691A/ko not_active Application Discontinuation
- 2006-08-14 AU AU2006279659A patent/AU2006279659A1/en not_active Abandoned
- 2006-08-14 JP JP2008526286A patent/JP2009504680A/ja active Pending
- 2006-08-14 AT AT06813425T patent/ATE509933T1/de not_active IP Right Cessation
- 2006-08-14 US US11/503,405 patent/US7749994B2/en not_active Expired - Fee Related
- 2006-08-14 BR BRPI0615141-8A patent/BRPI0615141A2/pt not_active IP Right Cessation
- 2006-08-14 RU RU2008108903/04A patent/RU2008108903A/ru not_active Application Discontinuation
2008
- 2008-02-05 IL IL189296A patent/IL189296A0/en unknown
- 2008-02-07 ZA ZA200801332A patent/ZA200801332B/xx unknown
- 2008-03-11 NO NO20081292A patent/NO20081292L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR20080035691A (ko)	2008-04-23
ZA200801332B (en)	2009-10-28
AU2006279659A1 (en)	2007-02-22
RU2008108903A (ru)	2009-09-20
CA2619276A1 (en)	2007-02-22
JP2009504680A (ja)	2009-02-05
ATE509933T1 (de)	2011-06-15
EP1919920B1 (en)	2011-05-18
WO2007022102A3 (en)	2007-05-10
BRPI0615141A2 (pt)	2009-07-14
EP1919920A2 (en)	2008-05-14
US7749994B2 (en)	2010-07-06
WO2007022102A2 (en)	2007-02-22
IL189296A0 (en)	2008-06-05
CN101287737A (zh)	2008-10-15
US20070037791A1 (en)	2007-02-15

Publication	Publication Date	Title
WO2007120333A3 (en)	2008-01-10	Tetracyclic kinase inhibitors
NO20073783L (no)	2007-09-19	Pyrrolidininhibitorer for IAP
NO20081292L (no)	2008-05-13	Pentasykliske kinaseinhibitorer
TW200740815A (en)	2007-11-01	P38 MAP kinase inhibitors and methods for using the same
TW200800999A (en)	2008-01-01	Novel compounds
EA200801428A1 (ru)	2008-10-30	Производные пиридиазинона для лечения опухолей
MX2009014247A (es)	2010-01-28	Compuestos heterociclicos utiles como inhibidores de mk2.
SE0302811D0 (sv)	2003-10-23	Novel compounds
CY1113192T1 (el)	2016-04-13	Ενωσεις και μεθοδοι για την αναστολη της μιτωτικης προοδου μεσω αναστολης της κινασης aurora
ATE479687T1 (de)	2010-09-15	Kinaseinhibitoren
ATE430747T1 (de)	2009-05-15	2-pyrimidinyl-pyrazolopyridin-erbb- kinaseinhibitoren
MX2007005932A (es)	2007-06-20	1-alquinil-2-ariloxialquilamidas y su uso como fungicidas.
ATE432281T1 (de)	2009-06-15	Pyrrolotriazin-kinasehemmer
ATE553106T1 (de)	2012-04-15	Heteroarylpyrrolopyridinone als kinaseinhibitoren
TW200728277A (en)	2007-08-01	Bicyclic derivatives as P38 inhibitors
MX2008001538A (es)	2008-04-04	Aril piridinas y metodos para su uso.
EA200801199A1 (ru)	2008-08-29	Ингибиторы киназы
CY1109916T1 (el)	2014-09-10	Βενζιμιδαζολο-θειοφαινικες ενωσεις ως plk αναστολεις
EA200701396A1 (ru)	2007-12-28	Триазолофталазины в качестве ингибиторов pde-2
WO2007097981A3 (en)	2007-10-25	Alpha carbolines and uses thereof
DE602005021894D1 (de)	2010-07-29	Triazolophthalazine
SE0301650D0 (sv)	2003-06-04	Novel compounds
TW200600499A (en)	2006-01-01	Novel amido-substituted hydroxy-6-phenylphenanthridines
TW200744612A (en)	2007-12-16	New combination
UA85505C2 (en)	2009-01-26	Kinase inhibitors

Legal Events

Date	Code	Title	Description
2013-03-25	FC2A	Withdrawal, rejection or dismissal of laid open patent application