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MX9203550A - Derivados de 4-aminoquinolina y su uso como medicamentos. - Google Patents

Derivados de 4-aminoquinolina y su uso como medicamentos.

Info

Publication number
MX9203550A
MX9203550A MX9203550A MX9203550A MX9203550A MX 9203550 A MX9203550 A MX 9203550A MX 9203550 A MX9203550 A MX 9203550A MX 9203550 A MX9203550 A MX 9203550A MX 9203550 A MX9203550 A MX 9203550A
Authority
MX
Mexico
Prior art keywords
6alkyl
phenyl
6alkanoyl
phenylc1
6alkylthio
Prior art date
Application number
MX9203550A
Other languages
English (en)
Inventor
Ife Robert John
Brown Thomas Henry
Leach Colin Andrew
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of MX9203550A publication Critical patent/MX9203550A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • C07D215/44Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX9203550A 1986-09-05 1992-06-26 Derivados de 4-aminoquinolina y su uso como medicamentos. MX9203550A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868621425A GB8621425D0 (en) 1986-09-05 1986-09-05 Compounds

Publications (1)

Publication Number Publication Date
MX9203550A true MX9203550A (es) 1992-09-01

Family

ID=10603729

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203550A MX9203550A (es) 1986-09-05 1992-06-26 Derivados de 4-aminoquinolina y su uso como medicamentos.

Country Status (28)

Country Link
US (2) US4806549A (es)
EP (1) EP0259174B1 (es)
JP (1) JPH07602B2 (es)
KR (1) KR950013850B1 (es)
CN (1) CN1019802B (es)
AT (1) ATE73776T1 (es)
AU (1) AU598299B2 (es)
CA (1) CA1308106C (es)
CZ (1) CZ398291A3 (es)
DE (1) DE3777505D1 (es)
DK (1) DK159308C (es)
EG (1) EG18408A (es)
ES (1) ES2033316T3 (es)
FI (1) FI88919C (es)
GB (1) GB8621425D0 (es)
GR (1) GR3004692T3 (es)
HU (1) HU199804B (es)
IE (1) IE61104B1 (es)
IL (1) IL83691A (es)
MX (1) MX9203550A (es)
MY (1) MY102689A (es)
NO (1) NO172388C (es)
NZ (1) NZ221663A (es)
PH (1) PH23695A (es)
PT (1) PT85651B (es)
WO (1) WO1988001621A1 (es)
ZA (1) ZA876581B (es)
ZW (1) ZW16787A1 (es)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5049567A (en) * 1988-02-25 1991-09-17 Smithkline Beckman Intercredit B.V. Substituted 4-aminoquinazoline derivatives and method of use
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2632305B1 (fr) * 1988-06-06 1992-05-15 Sanofi Sa Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
ES2112272T3 (es) * 1990-03-28 1998-04-01 Otsuka Pharma Co Ltd Derivado de quinolina, medicamento anti-ulceroso que contiene este derivado y produccion de este derivado.
GB9126438D0 (en) * 1991-12-12 1992-02-12 Smithkline Beecham Intercredit New quinoline derivatives
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
SE9302005D0 (sv) 1993-06-11 1993-06-11 Ab Astra New active compounds
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
IN188411B (es) * 1997-03-27 2002-09-21 Yuhan Corp
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
GB2396815B (en) * 1999-10-27 2004-09-08 Phytopharm Plc A composition comprising a pregnenone derivative and an NSAID
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
EP1453493A2 (en) * 2001-11-19 2004-09-08 ALTANA Pharma AG Reversible proton pump inhibitors for the treatment of airway disorders
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
US20050222193A1 (en) * 2002-05-07 2005-10-06 Guido Hanauer Novel combination for the treatment of airway disorders
WO2004012659A2 (en) * 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
US7470791B2 (en) 2003-03-10 2008-12-30 Nycomed Gmbh Process for the preparation of roflumilast
KR20060099524A (ko) 2003-11-03 2006-09-19 아스트라제네카 아베 무증상 위식도 역류의 치료를 위한 이미다조[1,2-a]피리딘유도체
SE0400284D0 (sv) * 2004-02-10 2004-02-10 Astrazeneca Ab Novel compounds
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
AU2007278986B2 (en) 2006-07-25 2010-09-16 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion using derivatives of small dicarboxylic acids in combination with PPI
CA2667682A1 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
TW200829555A (en) * 2006-11-10 2008-07-16 Astrazeneca Ab Chemical compounds
CL2008000191A1 (es) * 2007-01-25 2008-08-22 Astrazeneca Ab Compuestos derivados de 4-amino-cinnotina-3-carboxamida; inhibidores de csf-1r quinasa; su proceso de preparacion; y su uso para tratar el cancer.
WO2009105568A1 (en) 2008-02-20 2009-08-27 The Curators Of The University Of Missouri Composition comprising a combination of omeprazole and lansoprazole, and a buffering agent, and methods of using same
CN102089286A (zh) * 2008-05-07 2011-06-08 阿斯利康(瑞典)有限公司 化合物
US8247280B2 (en) 2009-10-20 2012-08-21 Taiwan Semiconductor Manufacturing Company, Ltd. Integration of low and high voltage CMOS devices
WO2019084271A1 (en) * 2017-10-25 2019-05-02 Children's Medical Center Corporation PAPD5 INHIBITORS AND METHODS OF USE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343804A (en) * 1979-03-26 1982-08-10 A. H. Robins Company, Inc. 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
PH22302A (en) * 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
EP0193329A3 (en) * 1985-02-22 1987-08-19 Beecham Group Plc Pyrazolopyridines, their preparation and pharmaceutical compositions containing them
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Also Published As

Publication number Publication date
DE3777505D1 (de) 1992-04-23
NO172388C (no) 1993-07-14
IE872370L (en) 1988-03-05
US4806550A (en) 1989-02-21
CN1019802B (zh) 1992-12-30
IL83691A (en) 1993-08-18
ES2033316T3 (es) 1993-03-16
NO881940D0 (no) 1988-05-04
EP0259174A1 (en) 1988-03-09
IE61104B1 (en) 1994-10-05
CA1308106C (en) 1992-09-29
DK159308B (da) 1990-10-01
GB8621425D0 (en) 1986-10-15
ZA876581B (en) 1989-04-26
DK245888D0 (da) 1988-05-05
JPH01500664A (ja) 1989-03-09
AU7874187A (en) 1988-03-24
CZ398291A3 (en) 1994-02-16
FI88919B (fi) 1993-04-15
GR3004692T3 (es) 1993-04-28
WO1988001621A1 (en) 1988-03-10
EG18408A (en) 1993-02-28
AU598299B2 (en) 1990-06-21
PT85651A (en) 1987-10-01
HUT47913A (en) 1989-04-28
ZW16787A1 (en) 1988-05-25
EP0259174B1 (en) 1992-03-18
ATE73776T1 (de) 1992-04-15
JPH07602B2 (ja) 1995-01-11
NO172388B (no) 1993-04-05
PT85651B (pt) 1990-05-31
CN87106163A (zh) 1988-03-16
FI882089A0 (fi) 1988-05-04
HU199804B (en) 1990-03-28
KR950013850B1 (ko) 1995-11-17
PH23695A (en) 1989-09-27
US4806549A (en) 1989-02-21
NO881940L (no) 1988-05-04
MY102689A (en) 1992-09-30
KR880701711A (ko) 1988-11-04
DK245888A (da) 1988-05-05
DK159308C (da) 1991-03-11
NZ221663A (en) 1989-08-29
FI882089A (fi) 1988-05-04
FI88919C (fi) 1993-07-26

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal