MX336229B - Microorganismos y metodos para la biosintesis de butadieno. - Google Patents
Microorganismos y metodos para la biosintesis de butadieno.Info
- Publication number
- MX336229B MX336229B MX2012012827A MX2012012827A MX336229B MX 336229 B MX336229 B MX 336229B MX 2012012827 A MX2012012827 A MX 2012012827A MX 2012012827 A MX2012012827 A MX 2012012827A MX 336229 B MX336229 B MX 336229B
- Authority
- MX
- Mexico
- Prior art keywords
- butadiene
- methods
- biosynthesis
- microorganisms
- organisms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C11/00—Aliphatic unsaturated hydrocarbons
- C07C11/12—Alkadienes
- C07C11/16—Alkadienes with four carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F136/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
- C08F136/02—Homopolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds
- C08F136/04—Homopolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds conjugated
- C08F136/06—Butadiene
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Botany (AREA)
- Polymers & Plastics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La presente invención se refiere a organismos microbianos que no se encuentran en la naturaleza que tienen una trayectoria butadieno. La invención adicionalmente proporciona métodos para utilizar tales organismos para producir butadieno. Un organismo microbiano de origen no natural que comprende, una senda biosintética para la producción de alcohol crotílico en donde dicha senda biosintética comprende por lo menos un ácido nucleico exógeno que codifica por lo menos una enzima de senda metabólica expresada en una cantidad suficiente para producir alcohol crotílico, en donde dicha enzima de la senda metabólica se selecciona a partir del grupo que consiste en una reductasa de4 crotonil-CoA, (formadora de aldehído), una reductasa de crotonaldehído (formadora de alcohol), una hidrolasa, sintetasa o transferasa, una reductasa de crotonil-CoA, una reductasa de crotonato, y una reductasa de crotonil-CoA (formadora de alcohol). Un método para la producción de alcohol crotílico que comprende cultivar el organismo microbiano de origen no natural, bajo condiciones y durante un periodo de tiempo suficiente para producir alcohol crotílico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33181210P | 2010-05-05 | 2010-05-05 | |
PCT/US2011/035105 WO2011140171A2 (en) | 2010-05-05 | 2011-05-04 | Microorganisms and methods for the biosynthesis of butadiene |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2012012827A MX2012012827A (es) | 2013-01-24 |
MX336229B true MX336229B (es) | 2016-01-08 |
Family
ID=45064763
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012012827A MX336229B (es) | 2010-05-05 | 2011-05-04 | Microorganismos y metodos para la biosintesis de butadieno. |
Country Status (13)
Country | Link |
---|---|
US (5) | US8580543B2 (es) |
EP (1) | EP2566969B1 (es) |
JP (3) | JP5911847B2 (es) |
KR (3) | KR101814648B1 (es) |
CN (2) | CN106047782A (es) |
AU (2) | AU2011248182A1 (es) |
BR (1) | BR112012028049A2 (es) |
CA (1) | CA2797409C (es) |
CO (1) | CO6630182A2 (es) |
MX (1) | MX336229B (es) |
SG (2) | SG185432A1 (es) |
TW (2) | TW201720931A (es) |
WO (1) | WO2011140171A2 (es) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009155382A1 (en) | 2008-06-17 | 2009-12-23 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
WO2010071697A1 (en) | 2008-12-16 | 2010-06-24 | Genomatica, Inc. | Microorganisms and methods for conversion of syngas and other carbon sources to useful products |
WO2010144746A2 (en) | 2009-06-10 | 2010-12-16 | Genomatica, Inc. | Microorganisms and methods for carbon-efficient biosynthesis of mek and 2-butanol |
WO2011071682A1 (en) | 2009-12-10 | 2011-06-16 | Genomatica, Inc. | Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol |
US8445244B2 (en) | 2010-02-23 | 2013-05-21 | Genomatica, Inc. | Methods for increasing product yields |
MX336229B (es) * | 2010-05-05 | 2016-01-08 | Genomatica Inc | Microorganismos y metodos para la biosintesis de butadieno. |
MX2013001071A (es) | 2010-07-26 | 2013-06-28 | Genomatica Inc | Microorganismos y metodos para la biosintesis de aromaticos, 2, 4-pentadienoato y 1, 3-butadieno. |
SG192614A1 (en) * | 2011-02-02 | 2013-09-30 | Genomatica Inc | Microorganisms and methods for the biosynthesis of butadiene |
US9422578B2 (en) | 2011-06-17 | 2016-08-23 | Invista North America S.A.R.L. | Methods for biosynthesizing 1,3 butadiene |
EP2721164A2 (en) | 2011-06-17 | 2014-04-23 | Invista Technologies S.à.r.l. | Methods of producing four carbon molecules |
US9169486B2 (en) * | 2011-06-22 | 2015-10-27 | Genomatica, Inc. | Microorganisms for producing butadiene and methods related thereto |
WO2013028519A1 (en) * | 2011-08-19 | 2013-02-28 | Genomatica, Inc. | Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols |
BR112014008061A2 (pt) * | 2011-10-19 | 2017-04-11 | Scientist Of Fortune Sa | método para a produção enzimática de butadieno |
CN104039974B (zh) * | 2011-11-09 | 2016-10-12 | 阿迈瑞斯公司 | 乙酰辅酶a衍生的类异戊二烯的生产 |
CN104321434A (zh) * | 2011-12-02 | 2015-01-28 | 英威达技术有限责任公司 | 生物合成1,3丁二烯的方法 |
CN104471068A (zh) * | 2011-12-16 | 2015-03-25 | 布拉斯科南美公司(巴西) | 经修饰的微生物和使用其制造丁二烯的方法 |
EP2794891A2 (en) * | 2011-12-20 | 2014-10-29 | Scientist of Fortune S.A. | Production of 1,3-dienes by enzymatic conversion of 3-hydroxyalk-4-enoates and/or 3-phosphonoxyalk-4-enoates |
US20150017698A1 (en) * | 2012-03-02 | 2015-01-15 | Codexis, Inc. a corporation | Recombinant host cells and processes for producing 1,3-butadiene through a 5-hydroxypent-3-enoate intermediate |
WO2013130481A1 (en) * | 2012-03-02 | 2013-09-06 | Codexis, Inc. | Recombinant host cells and processes for producing 1,3-butadiene through a crotonol intermediate |
EP2850180A1 (en) | 2012-05-18 | 2015-03-25 | Novozymes A/S | Bacterial mutants with improved transformation efficiency |
EP2861745A2 (en) * | 2012-06-15 | 2015-04-22 | Invista Technologies S.à.r.l. | Methods for biosynthesizing 1,3 butadiene |
BR112014031894A2 (pt) * | 2012-06-18 | 2017-08-01 | Braskem Sa | método para co-produção de butadieno e 1-propanol e/ou 1, 2-propanodiol e, microrganismo |
US20150211024A1 (en) * | 2012-08-28 | 2015-07-30 | Braskem S.A. | Methods for production of a terpene and a co-product |
EP2900689B1 (en) | 2012-09-27 | 2017-08-02 | Novozymes, Inc. | Bacterial mutants with improved transformation efficiency |
WO2014055649A1 (en) * | 2012-10-02 | 2014-04-10 | Braskem S/A Ap 09 | Modified microorganisms and methods of using same for producing butadiene and succinate |
WO2014063156A2 (en) * | 2012-10-19 | 2014-04-24 | Braskem S/A Ap 09 | Modified microorganisms and methods of using same for producing butadiene and one or more of 1,3-butanediol, 1,4-butanediol, and/or 1,3-propanediol |
WO2014066235A1 (en) * | 2012-10-22 | 2014-05-01 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing succinate related thereto |
EP2920314A1 (en) * | 2012-11-13 | 2015-09-23 | Global Bioenergies | Process for the enzymatic preparation of isoprene from isoprenol |
WO2014081973A1 (en) | 2012-11-21 | 2014-05-30 | The Regents Of The University Of California | Nucleic acids useful for integrating into and gene expression in hyperthermophilic acidophilic archaea |
US9777295B2 (en) | 2012-11-28 | 2017-10-03 | Invista North America S.A.R.L. | Methods for biosynthesis of isobutene |
JP6304924B2 (ja) * | 2012-11-29 | 2018-04-04 | 住友ゴム工業株式会社 | サイドウォール用ゴム組成物、及び空気入りタイヤ |
WO2014089025A1 (en) * | 2012-12-04 | 2014-06-12 | Genomatica, Inc. | Increased yields of biosynthesized products |
WO2014106122A1 (en) * | 2012-12-31 | 2014-07-03 | Genomatica, Inc. | Compositions and methods for bio-butadiene production screening |
JP2014155455A (ja) * | 2013-02-15 | 2014-08-28 | Sekisui Chem Co Ltd | 組換え細胞、並びに、クロトニルCoA又はクロチルアルコールの生産方法 |
JP2014161252A (ja) * | 2013-02-22 | 2014-09-08 | Sekisui Chem Co Ltd | 組換え細胞 |
EP2971021A4 (en) | 2013-03-15 | 2016-12-21 | Genomatica Inc | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY ASSIMILATING FORMAT |
CN105518130A (zh) | 2013-06-21 | 2016-04-20 | 丹尼斯科美国公司 | 用于梭菌转化的组合物和方法 |
US10294496B2 (en) | 2013-07-19 | 2019-05-21 | Invista North America S.A.R.L. | Methods for biosynthesizing 1,3 butadiene |
EP3030668A1 (en) | 2013-08-05 | 2016-06-15 | Invista Technologies S.A R.L. | Methods for biosynthesis of isobutene |
BR112016002625A2 (pt) | 2013-08-05 | 2017-09-12 | Invista Tech Sarl | método para sintetizar enzimaticamente isopreno e hospedeiro recombinante produtor de isopreno |
US10808262B2 (en) | 2013-12-03 | 2020-10-20 | Genomatica, Inc. | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis |
CN113416686B (zh) | 2013-12-27 | 2024-08-06 | 基因组股份公司 | 具有增加的碳通量效率的方法和生物 |
US10273490B2 (en) | 2014-03-27 | 2019-04-30 | Photanol B.V. | Erythritol production in cyanobacteria |
US9920339B2 (en) | 2014-06-16 | 2018-03-20 | Invista North America S.A.R.L. | Methods, reagents and cells for biosynthesizing compounds |
WO2016007365A1 (en) * | 2014-07-11 | 2016-01-14 | Genomatica, Inc. | Microorganisms and methods for the production of butadiene using acetyl-coa |
US20170298363A1 (en) | 2014-09-18 | 2017-10-19 | Genomatica, Inc | Non-natural microbial organisms with improved energetic efficiency |
CN104298866B (zh) * | 2014-09-30 | 2017-06-06 | 杭州电子科技大学 | 一种克劳斯硫磺回收过程中反应炉动态建模方法 |
JP6432774B2 (ja) * | 2014-12-25 | 2018-12-05 | 江南化工株式会社 | 細胞賦活剤 |
EP3273782B9 (en) | 2015-02-27 | 2022-07-13 | White Dog Labs, Inc. | Mixotrophic fermentation method for making acetone, isopropanol, and other bioproducts, and mixtures thereof |
WO2016160812A1 (en) * | 2015-03-31 | 2016-10-06 | White Dog Labs, Inc. | Method of producing bioproducts |
WO2016164586A1 (en) | 2015-04-09 | 2016-10-13 | Genomatica, Inc. | Engineered microorganisms & methods for improved crotyl alcohol production |
US10941454B2 (en) | 2015-05-30 | 2021-03-09 | Genomatica, Inc. | Vinylisomerase-dehydratases, alkenol dehydratases, linalool dehydratases and crotyl alcohol dehydratases and methods for making and using them |
WO2017064606A1 (en) * | 2015-10-12 | 2017-04-20 | Reliance Industries Limited | Process for preparation of 1,3-butadiene |
CN115322261A (zh) | 2015-10-30 | 2022-11-11 | 基因组股份公司 | 甲醇脱氢酶融合蛋白 |
GB201605354D0 (en) | 2016-03-30 | 2016-05-11 | Zuvasyntha Ltd | Modified enzyme |
US10919030B2 (en) | 2016-09-30 | 2021-02-16 | Regents Of The University Of Minnesota | Forming dienes from cyclic ethers and diols, including tetrahydrofuran and 2-methyl-1,4-butanediol |
JP6317497B2 (ja) * | 2017-03-22 | 2018-04-25 | 住友ゴム工業株式会社 | トレッド用ゴム組成物、及び空気入りタイヤ |
JP6317498B2 (ja) * | 2017-03-22 | 2018-04-25 | 住友ゴム工業株式会社 | スタッドレスタイヤ用トレッド用ゴム組成物、及びスタッドレスタイヤ |
US11162115B2 (en) | 2017-06-30 | 2021-11-02 | Inv Nylon Chemicals Americas, Llc | Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons |
US11634733B2 (en) | 2017-06-30 | 2023-04-25 | Inv Nylon Chemicals Americas, Llc | Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof |
US11505809B2 (en) | 2017-09-28 | 2022-11-22 | Inv Nylon Chemicals Americas Llc | Organisms and biosynthetic processes for hydrocarbon synthesis |
US20210079334A1 (en) | 2018-01-30 | 2021-03-18 | Genomatica, Inc. | Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component |
US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
US20220177895A1 (en) | 2018-06-26 | 2022-06-09 | Genomatica, Inc. | Engineered microorganisms with g3p -> 3pg enzyme and/or fructose-1,6-bisphosphatase including those having synthetic or enhanced methylotrophy |
US20220258100A1 (en) * | 2019-07-16 | 2022-08-18 | San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation | Products of manufacture and methods for methane capturing using biofiltration |
Family Cites Families (158)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3513209A (en) | 1968-08-19 | 1970-05-19 | Du Pont | Method of making 1,4-cyclohexadiene |
US4076948A (en) | 1968-10-10 | 1978-02-28 | El Paso Products Company | Process for treatment of adipic acid mother liquor |
GB1230276A (es) | 1968-12-09 | 1971-04-28 | ||
US3965182A (en) | 1969-10-02 | 1976-06-22 | Ethyl Corporation | Preparation of aniline from phenol and ammonia |
JPS4831084B1 (es) | 1970-09-04 | 1973-09-26 | ||
GB1344557A (en) | 1972-06-23 | 1974-01-23 | Mitsubishi Petrochemical Co | Process for preparing 1,4-butanediol |
JPS5543759B2 (es) | 1972-06-28 | 1980-11-07 | ||
DE2455617C3 (de) | 1974-11-23 | 1982-03-18 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von Butandiol und/oder Tetrahydrofuran über die Zwischenstufe des γ-Butyrolactons |
DE2501499A1 (de) | 1975-01-16 | 1976-07-22 | Hoechst Ag | Verfahren zur herstellung von butandiol-(1.4) |
US4190495A (en) | 1976-09-27 | 1980-02-26 | Research Corporation | Modified microorganisms and method of preparing and using same |
US4301077A (en) | 1980-12-22 | 1981-11-17 | Standard Oil Company | Process for the manufacture of 1-4-butanediol and tetrahydrofuran |
JPS60114197A (ja) | 1983-11-25 | 1985-06-20 | Agency Of Ind Science & Technol | 微生物によるジカルボン酸の製造法 |
US4871667A (en) | 1984-11-26 | 1989-10-03 | Agency Of Industrial Science & Technology | Process for preparing muconic acid |
US4652685A (en) | 1985-11-15 | 1987-03-24 | General Electric Company | Hydrogenation of lactones to glycols |
US5143834A (en) | 1986-06-11 | 1992-09-01 | Glassner David A | Process for the production and purification of succinic acid |
US5168055A (en) | 1986-06-11 | 1992-12-01 | Rathin Datta | Fermentation and purification process for succinic acid |
EP0249773B1 (en) | 1986-06-11 | 1992-12-16 | Michigan Biotechnology Institute | A process for the production of succinic acid by anaerobic fermentation |
US5182199A (en) | 1987-05-27 | 1993-01-26 | Hartley Brian S | Thermophilic ethanol production in a two-stage closed system |
JPH01195596A (ja) | 1988-01-30 | 1989-08-07 | Casio Comput Co Ltd | 値札システム |
EP0633319B1 (en) | 1988-04-27 | 1999-03-17 | Daicel Chemical Industries, Ltd. | Process for producing optically active 1,3-butanediol |
DE69020555T2 (de) | 1989-04-27 | 1995-11-02 | Biocontrol Systems Inc | Fällungstest für mikroorganismen. |
US5192673A (en) | 1990-04-30 | 1993-03-09 | Michigan Biotechnology Institute | Mutant strain of C. acetobutylicum and process for making butanol |
US5079143A (en) | 1990-05-02 | 1992-01-07 | The Upjohn Company | Method of indentifying compounds useful as antiparasitic drugs |
DE69126298T2 (de) | 1990-10-15 | 1997-09-04 | Daicel Chem | Verfahren zur Herstellung optisch aktiven (R)-1,3-Butanediols mittels eines Mikroorganismus der Gattung Rhodococcus |
US5173429A (en) | 1990-11-09 | 1992-12-22 | The Board Of Trustees Of The University Of Arkansas | Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism |
IL100572A (en) | 1991-01-03 | 1997-01-10 | Lepetit Spa | Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them |
US5416020A (en) | 1992-09-29 | 1995-05-16 | Bio-Technical Resources | Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid |
US6136577A (en) | 1992-10-30 | 2000-10-24 | Bioengineering Resources, Inc. | Biological production of ethanol from waste gases with Clostridium ljungdahlii |
US5807722A (en) | 1992-10-30 | 1998-09-15 | Bioengineering Resources, Inc. | Biological production of acetic acid from waste gases with Clostridium ljungdahlii |
FR2702492B1 (fr) | 1993-03-12 | 1995-05-24 | Rhone Poulenc Chimie | Procédé de production par fermentation d'acide itaconique. |
US5487987A (en) | 1993-09-16 | 1996-01-30 | Purdue Research Foundation | Synthesis of adipic acid from biomass-derived carbon sources |
US5521075A (en) | 1994-12-19 | 1996-05-28 | Michigan Biotechnology Institute | Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants |
US5504004A (en) | 1994-12-20 | 1996-04-02 | Michigan Biotechnology Institute | Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms |
US5700934A (en) | 1995-03-01 | 1997-12-23 | Dsm N.V. | Process for the preparation of epsilon-caprolactam and epsilon-caprolactam precursors |
US5478952A (en) | 1995-03-03 | 1995-12-26 | E. I. Du Pont De Nemours And Company | Ru,Re/carbon catalyst for hydrogenation in aqueous solution |
US5863782A (en) | 1995-04-19 | 1999-01-26 | Women's And Children's Hospital | Synthetic mammalian sulphamidase and genetic sequences encoding same |
US5686276A (en) | 1995-05-12 | 1997-11-11 | E. I. Du Pont De Nemours And Company | Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism |
US5849970A (en) | 1995-06-23 | 1998-12-15 | The Regents Of The University Of Colorado | Materials and methods for the bacterial production of isoprene |
FR2736927B1 (fr) | 1995-07-18 | 1997-10-17 | Rhone Poulenc Fibres & Polymer | Enzymes a activite amidase, outils genetiques et microorganismes hotes permettant leur obtention et procede d'hydrolyse mettant en oeuvre lesdites enzymes |
US5573931A (en) | 1995-08-28 | 1996-11-12 | Michigan Biotechnology Institute | Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants |
US5869301A (en) | 1995-11-02 | 1999-02-09 | Lockhead Martin Energy Research Corporation | Method for the production of dicarboxylic acids |
US5770435A (en) | 1995-11-02 | 1998-06-23 | University Of Chicago | Mutant E. coli strain with increased succinic acid production |
WO1997032012A1 (en) | 1996-02-27 | 1997-09-04 | Michigan State University | Cloning and expression of the gene encoding thermoanaerobacter ethanolicus 39e secondary-alcohol dehydrogenase and enzyme biochemical characterization |
US5958745A (en) | 1996-03-13 | 1999-09-28 | Monsanto Company | Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants |
KR100387301B1 (ko) | 1996-07-01 | 2003-06-12 | 바이오 엔지니어링 리소스 인코포레이티드 | 폐가스로부터의 생성물의 생물학적 제조방법 |
KR100459818B1 (ko) | 1996-09-02 | 2004-12-03 | 이. 아이. 두퐁 드 느무르 앤드 컴퍼니 | ε-카프로락탐의 제조방법 |
WO1998036078A1 (en) | 1997-02-13 | 1998-08-20 | James Madison University | Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units |
KR100516986B1 (ko) | 1997-02-19 | 2005-09-26 | 코닌클리즈케 디에스엠 엔.브이. | 6-아미노카프론산 유도체를 과열 수증기와 접촉시킴으로써 촉매 없이 카프로락탐을 제조하는 방법 |
US6274790B1 (en) | 1997-04-14 | 2001-08-14 | The University Of British Columbia | Nucleic acids encoding a plant enzyme involved in very long chain fatty acid synthesis |
KR19990013007A (ko) | 1997-07-31 | 1999-02-25 | 박원훈 | 형질전환된 대장균 ss373(kctc 8818p)과 이를 이용한숙신산의 생산방법 |
JPH11103863A (ja) | 1997-10-08 | 1999-04-20 | Nippon Shokubai Co Ltd | マレイン酸異性化酵素遺伝子 |
US6280986B1 (en) | 1997-12-01 | 2001-08-28 | The United States Of America As Represented By The Secretary Of Agriculture | Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities |
CA2325598A1 (en) | 1998-04-13 | 1999-10-21 | The University Of Georgia Research Foundation, Inc. | Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells |
US20030087381A1 (en) | 1998-04-13 | 2003-05-08 | University Of Georgia Research Foundation, Inc. | Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals |
US6159738A (en) | 1998-04-28 | 2000-12-12 | University Of Chicago | Method for construction of bacterial strains with increased succinic acid production |
DE19820652A1 (de) | 1998-05-08 | 1999-11-11 | Basf Ag | Kationische Rutheniumkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung |
US6432686B1 (en) | 1998-05-12 | 2002-08-13 | E. I. Du Pont De Nemours And Company | Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport |
US6444784B1 (en) | 1998-05-29 | 2002-09-03 | Exxonmobil Research & Engineering Company | Wax crystal modifiers (LAW657) |
WO2000004163A1 (en) | 1998-07-15 | 2000-01-27 | E.I. Du Pont De Nemours And Company | Tetrahydrofolate metabolism enzymes |
DE19856136C2 (de) | 1998-12-04 | 2002-10-24 | Pasteur Institut | Verfahren und Vorrichtung zur Selektion beschleunigter Proliferation lebender Zellen in Suspension |
EP1147229A2 (en) | 1999-02-02 | 2001-10-24 | Bernhard O. Palsson | Methods for identifying drug targets based on genomic sequence data |
US6686310B1 (en) | 1999-02-09 | 2004-02-03 | E. I. Du Pont De Nemours And Company | High surface area sol-gel route prepared hydrogenation catalysts |
US6365376B1 (en) | 1999-02-19 | 2002-04-02 | E. I. Du Pont De Nemours And Company | Genes and enzymes for the production of adipic acid intermediates |
AU3516100A (en) | 1999-03-05 | 2000-09-21 | Monsanto Technology Llc | Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways |
EP1183385B1 (en) | 1999-05-21 | 2006-07-19 | Cargill Dow LLC | Methods and materials for the synthesis of organic products |
US6852517B1 (en) | 1999-08-30 | 2005-02-08 | Wisconsin Alumni Research Foundation | Production of 3-hydroxypropionic acid in recombinant organisms |
US6660857B2 (en) | 2000-02-03 | 2003-12-09 | Dsm N.V. | Process for the preparation of ε-caprolactam |
US6878861B2 (en) | 2000-07-21 | 2005-04-12 | Washington State University Research Foundation | Acyl coenzyme A thioesterases |
PT1303629E (pt) | 2000-07-25 | 2006-10-31 | Emmaus Foundation Inc | Metodos para aumentar a producao de etanol a partir da fermantacao microbiana |
CA2429039A1 (en) | 2000-11-20 | 2002-05-30 | Cargill, Incorporated | 3-hydroxypropionic acid and other organic compounds |
JP2004521619A (ja) | 2000-11-22 | 2004-07-22 | カージル ダウ ポリマーズ エルエルシー | 有機生成物の合成のための方法及び材料 |
CN1358841A (zh) | 2000-12-11 | 2002-07-17 | 云南省微生物研究所 | 云南链霉菌 |
CA2433529A1 (en) | 2000-12-28 | 2002-07-11 | Toyota Jidosha Kabushiki Kaisha | Process for producing prenyl alcohol |
JP4776146B2 (ja) | 2001-01-10 | 2011-09-21 | ザ・ペン・ステート・リサーチ・ファンデーション | 細胞代謝をモデル化する方法及びシステム |
US7127379B2 (en) | 2001-01-31 | 2006-10-24 | The Regents Of The University Of California | Method for the evolutionary design of biochemical reaction networks |
EP1381860A4 (en) | 2001-03-01 | 2008-10-15 | Univ California | MODELS AND METHOD FOR DETERMINING SYSTEMIC PROPERTIES OF REGULATED RESPONSE NETWORKS |
US6743610B2 (en) | 2001-03-30 | 2004-06-01 | The University Of Chicago | Method to produce succinic acid from raw hydrolysates |
JP4630486B2 (ja) | 2001-05-28 | 2011-02-09 | ダイセル化学工業株式会社 | 新規な(r)−2,3−ブタンジオール脱水素酵素、その製造方法、及びこれを利用した光学活性アルコールの製造方法 |
CA2356540A1 (en) | 2001-08-30 | 2003-02-28 | Emory University | Expressed dna sequences involved in mitochondrial functions |
MXPA04004194A (es) | 2001-11-02 | 2005-03-31 | Rice University | Sistema de recirculacion para la manipulacion de disponibilidad de nadh intracelular. |
ATE432338T1 (de) | 2002-01-18 | 2009-06-15 | Novozymes As | Alanin-2,3-aminomutase |
AU2003211492A1 (en) | 2002-02-06 | 2003-09-02 | Showa Denko K.K. | Alpha-SUBSTITUTED-Alpha,Beta-UNSATURATED CARBONYL COMPOUND REDUCTASE GENE |
US20030224363A1 (en) | 2002-03-19 | 2003-12-04 | Park Sung M. | Compositions and methods for modeling bacillus subtilis metabolism |
EP1495321A4 (en) | 2002-03-29 | 2006-10-25 | Genomatica Inc | HUMAN METABOLISM MODELS AND ASSOCIATED METHODS |
WO2003095651A1 (fr) | 2002-05-10 | 2003-11-20 | Kyowa Hakko Kogyo Co., Ltd. | Procede de production d'acide mevalonique |
US7856317B2 (en) | 2002-06-14 | 2010-12-21 | Genomatica, Inc. | Systems and methods for constructing genomic-based phenotypic models |
CA2491753A1 (en) | 2002-07-10 | 2004-03-04 | The Penn State Research Foundation | Method for determining gene knockout strategies |
US7826975B2 (en) | 2002-07-10 | 2010-11-02 | The Penn State Research Foundation | Method for redesign of microbial production systems |
US7413878B2 (en) | 2002-07-15 | 2008-08-19 | Kosan Biosciences, Inc. | Recombinant host cells expressing atoAD and capable of making a polyketide using a starter unit |
MXPA05003382A (es) | 2002-10-04 | 2005-06-22 | Du Pont | Proceso para la produccion biologica de 1,3-propanodiol con alto rendimiento. |
AU2003222214B2 (en) | 2002-10-15 | 2010-08-12 | The Regents Of The University Of California | Methods and systems to identify operational reaction pathways |
US20040152159A1 (en) | 2002-11-06 | 2004-08-05 | Causey Thomas B. | Materials and methods for the efficient production of acetate and other products |
US7960599B2 (en) | 2003-01-13 | 2011-06-14 | Elevance Renewable Sciences, Inc. | Method for making industrial chemicals |
WO2004074495A1 (ja) | 2003-02-24 | 2004-09-02 | Research Institute Of Innovative Technology For The Earth | 微生物による高効率水素製造方法 |
RU2268300C2 (ru) | 2003-04-07 | 2006-01-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA |
JP4451393B2 (ja) | 2003-07-29 | 2010-04-14 | 財団法人地球環境産業技術研究機構 | コリネ型細菌形質転換体及びそれを用いるジカルボン酸の製造方法 |
US7927859B2 (en) | 2003-08-22 | 2011-04-19 | Rice University | High molar succinate yield bacteria by increasing the intracellular NADH availability |
BRPI0414300A (pt) | 2003-09-17 | 2006-11-07 | Mitsubishi Chem Corp | método para produzir ácido orgánico não amino |
US7244610B2 (en) | 2003-11-14 | 2007-07-17 | Rice University | Aerobic succinate production in bacteria |
FR2864967B1 (fr) | 2004-01-12 | 2006-05-19 | Metabolic Explorer Sa | Microorganisme evolue pour la production de 1,2-propanediol |
DE602005018898D1 (de) | 2004-01-19 | 2010-03-04 | Dsm Ip Assets Bv | Biochemische synthese von 6-aminocapronsäure |
US7608700B2 (en) | 2004-03-08 | 2009-10-27 | North Carolina State University | Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor |
DE102004031177A1 (de) | 2004-06-29 | 2006-01-19 | Henkel Kgaa | Neue Geruchsstoffe bildende Genprodukte von Bacillus licheniformis und darauf aufbauende verbesserte biotechnologische Produktionsverfahren |
US7262046B2 (en) | 2004-08-09 | 2007-08-28 | Rice University | Aerobic succinate production in bacteria |
CA2578028A1 (en) * | 2004-08-26 | 2006-03-09 | Costas D. Maranas | Method for redesign of microbial production systems |
US7223567B2 (en) | 2004-08-27 | 2007-05-29 | Rice University | Mutant E. coli strain with increased succinic acid production |
EP2434015B1 (en) | 2004-09-09 | 2013-11-20 | Research Institute Of Innovative Technology For The Earth | DNA fragment having promoter function |
US20060073577A1 (en) | 2004-09-17 | 2006-04-06 | San Ka-Yiu | High succinate producing bacteria |
DE602005013993D1 (de) | 2004-10-14 | 2009-05-28 | Sumitomo Chemical Co | Verfahren zur herstellung von 2-hydroxy-4-(methylthio)butansäure |
US7569380B2 (en) | 2004-12-22 | 2009-08-04 | Rice University | Simultaneous anaerobic production of isoamyl acetate and succinic acid |
DE102005002127A1 (de) * | 2005-01-17 | 2006-07-20 | Basf Ag | Verfahren zur Herstellung von Butadien aus n-Butan |
JP2006204255A (ja) | 2005-01-31 | 2006-08-10 | Canon Inc | アセチル−CoAアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法 |
EP1874334A4 (en) | 2005-04-15 | 2011-03-30 | Vascular Biogenics Ltd | COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES |
KR100679638B1 (ko) | 2005-08-19 | 2007-02-06 | 한국과학기술원 | 포메이트 디하이드로게나제 d 또는 e를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법 |
KR100676160B1 (ko) | 2005-08-19 | 2007-02-01 | 한국과학기술원 | 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법 |
EP1937821A4 (en) | 2005-09-09 | 2009-11-11 | Genomatica Inc | PROCESS AND ORGANISMS FOR GROWTH-COUPLED PRODUCTION OF SUCCINATE |
US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US7851188B2 (en) | 2005-10-26 | 2010-12-14 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
GB2433260A (en) | 2005-12-16 | 2007-06-20 | Mologic Ltd | A selectable decarboxylase marker |
US8962298B2 (en) | 2006-05-02 | 2015-02-24 | Butamax Advanced Biofuels Llc | Recombinant host cell comprising a diol dehydratase |
DE102006025821A1 (de) | 2006-06-02 | 2007-12-06 | Degussa Gmbh | Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd |
US8017364B2 (en) | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
US20100210017A1 (en) | 2007-01-12 | 2010-08-19 | Gill Ryan T | Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms |
TWI488964B (zh) | 2007-03-16 | 2015-06-21 | Genomatica Inc | 用於1,4丁二醇及其前驅物之生物合成的組合物及方法 |
EP2147111A4 (en) | 2007-04-18 | 2010-06-23 | Gevo Inc | MANIPULATED MICROORGANISMS FOR THE MANUFACTURE OF ISOPROPANOL |
US20080274522A1 (en) | 2007-05-02 | 2008-11-06 | Bramucci Michael G | Method for the production of 2-butanone |
US9080187B2 (en) | 2007-05-17 | 2015-07-14 | The Board Of Trustees Of The University Of Illinois | Methods and compositions for producing solvents |
EP2017344A1 (en) | 2007-07-20 | 2009-01-21 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | Production of itaconic acid |
US20100205857A1 (en) | 2007-07-23 | 2010-08-19 | Einte-Karst Dijk | Butanol production in a eukaryotic cell |
US7947483B2 (en) | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
WO2009049274A2 (en) | 2007-10-12 | 2009-04-16 | The Regents Of The University Of California | Microorganism engineered to produce isopropanol |
MX2010006576A (es) * | 2007-12-13 | 2010-10-15 | Danisco Us Inc | Composiciones y metodos para producir isopreno. |
WO2009085278A1 (en) | 2007-12-21 | 2009-07-09 | Ls9, Inc. | Methods and compositions for producing olefins |
US7803589B2 (en) | 2008-01-22 | 2010-09-28 | Genomatica, Inc. | Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol |
EP2706111A1 (en) * | 2008-03-03 | 2014-03-12 | Joule Unlimited Technologies, Inc. | Engineered CO2 fixing microorganisms producing carbon-based products of interest |
CA2995870C (en) | 2008-03-27 | 2022-11-01 | Genomatica, Inc. | Microorganisms for the production of adipic acid and other compounds |
EP2279251A2 (en) | 2008-04-23 | 2011-02-02 | Danisco US Inc. | Isoprene synthase variants for improved microbial production of isoprene |
US8241877B2 (en) | 2008-05-01 | 2012-08-14 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
WO2009155382A1 (en) | 2008-06-17 | 2009-12-23 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
US8420759B2 (en) | 2008-06-30 | 2013-04-16 | The Goodyear Tire & Rubber Company | Polymers of isoprene from renewable resources |
EP2313491A4 (en) | 2008-07-08 | 2011-12-07 | Opx Biotechnologies Inc | METHODS, COMPOSITIONS AND SYSTEMS FOR BIOSYNTHETIC BIOPRODUCTION OF 1,4-BUTANEDIOL |
WO2010022763A1 (en) | 2008-08-25 | 2010-03-04 | Metabolic Explorer | Method for the preparation of 2-hydroxy-isobutyrate |
JP5912529B2 (ja) * | 2008-09-10 | 2016-04-27 | ゲノマチカ, インク. | 1,4−ブタンジオールの生成のための微生物体 |
EP2337845A1 (en) * | 2008-09-15 | 2011-06-29 | Danisco US Inc. | Increased isoprene production using mevalonate kinase and isoprene synthase |
WO2010031079A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Systems using cell culture for production of isoprene |
US8344188B2 (en) | 2008-10-16 | 2013-01-01 | Maverick Biofuels, Inc. | Methods and apparatus for synthesis of alcohols from syngas |
KR20160025043A (ko) | 2008-12-12 | 2016-03-07 | 메타볼릭스 인코포레이티드 | 폴리(5hv)및 5 탄소 화학물질의 생산을 위한 녹색 공정 및 조성물 |
WO2010071697A1 (en) | 2008-12-16 | 2010-06-24 | Genomatica, Inc. | Microorganisms and methods for conversion of syngas and other carbon sources to useful products |
EP3865569B1 (en) * | 2009-04-30 | 2023-10-04 | Genomatica, Inc. | Organisms for the production of 1,3-butanediol |
CN113528417A (zh) | 2009-06-04 | 2021-10-22 | 基因组股份公司 | 生产1,4-丁二醇的微生物和相关方法 |
US20120276606A1 (en) | 2009-10-30 | 2012-11-01 | Daicel Corporation | Recombinant microorganisms with 1,3-butanediol-producing function and uses thereof |
WO2011071682A1 (en) | 2009-12-10 | 2011-06-16 | Genomatica, Inc. | Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol |
MX336229B (es) * | 2010-05-05 | 2016-01-08 | Genomatica Inc | Microorganismos y metodos para la biosintesis de butadieno. |
SG192614A1 (en) * | 2011-02-02 | 2013-09-30 | Genomatica Inc | Microorganisms and methods for the biosynthesis of butadiene |
US9169486B2 (en) * | 2011-06-22 | 2015-10-27 | Genomatica, Inc. | Microorganisms for producing butadiene and methods related thereto |
BR112014008061A2 (pt) * | 2011-10-19 | 2017-04-11 | Scientist Of Fortune Sa | método para a produção enzimática de butadieno |
US20150050708A1 (en) * | 2013-03-15 | 2015-02-19 | Genomatica, Inc. | Microorganisms and methods for producing butadiene and related compounds by formate assimilation |
EP2971021A4 (en) * | 2013-03-15 | 2016-12-21 | Genomatica Inc | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY ASSIMILATING FORMAT |
-
2011
- 2011-05-04 MX MX2012012827A patent/MX336229B/es unknown
- 2011-05-04 CA CA2797409A patent/CA2797409C/en not_active Expired - Fee Related
- 2011-05-04 JP JP2013509203A patent/JP5911847B2/ja active Active
- 2011-05-04 SG SG2012081519A patent/SG185432A1/en unknown
- 2011-05-04 WO PCT/US2011/035105 patent/WO2011140171A2/en active Application Filing
- 2011-05-04 BR BR112012028049A patent/BR112012028049A2/pt not_active IP Right Cessation
- 2011-05-04 EP EP11778232.6A patent/EP2566969B1/en active Active
- 2011-05-04 SG SG10201503501TA patent/SG10201503501TA/en unknown
- 2011-05-04 US US13/101,046 patent/US8580543B2/en active Active
- 2011-05-04 CN CN201610340556.4A patent/CN106047782A/zh active Pending
- 2011-05-04 KR KR1020127031134A patent/KR101814648B1/ko active IP Right Grant
- 2011-05-04 AU AU2011248182A patent/AU2011248182A1/en not_active Abandoned
- 2011-05-04 CN CN201180033199.2A patent/CN103080324B/zh active Active
- 2011-05-04 KR KR1020197001071A patent/KR20190006103A/ko not_active Application Discontinuation
- 2011-05-04 KR KR1020177037394A patent/KR20180005263A/ko active Application Filing
- 2011-05-05 TW TW105130341A patent/TW201720931A/zh unknown
- 2011-05-05 TW TW100115805A patent/TWI575072B/zh not_active IP Right Cessation
-
2012
- 2012-11-06 CO CO12199796A patent/CO6630182A2/es unknown
-
2013
- 2013-10-21 US US14/059,131 patent/US9732361B2/en active Active
-
2016
- 2016-02-26 AU AU2016201231A patent/AU2016201231A1/en not_active Abandoned
- 2016-03-30 JP JP2016068884A patent/JP2016154551A/ja active Pending
-
2017
- 2017-07-10 US US15/645,880 patent/US10487343B2/en not_active Expired - Fee Related
-
2018
- 2018-08-16 JP JP2018153224A patent/JP2018196387A/ja active Pending
-
2019
- 2019-10-25 US US16/664,648 patent/US20200299736A1/en not_active Abandoned
-
2021
- 2021-03-05 US US17/193,914 patent/US20220025411A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2012012827A (es) | Microorganismos y metodos para la biosintesis de butadieno. | |
MY179664A (en) | Microorganisms and methods for the biosynthesis of butadiene | |
EP2563926A4 (en) | MICROORGANISMS AND METHODS OF PROPYLENE BIOSYNTHESIS | |
MX2012008738A (es) | Microorganismos y metodos para la biosintesis de p-toluato y tereftalato. | |
EP2558582A4 (en) | MICROORGANISMS AND PROCESSES FOR THE PRODUCTION OF ETHYLENE GLYCOL | |
EP3312284A3 (en) | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | |
PH12015502401A1 (en) | Compositions and methods for enhancing microbial stability | |
PH12015501470A1 (en) | Compositions and methods for the control of nematodes and soil borne diseases | |
MY179933A (en) | Certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use thereof | |
AU2016204248A1 (en) | Boron-Containing Molecules | |
MX2010000348A (es) | Cultivo de celulas madre pluripotentes individuales. | |
IN2015DN01198A (es) | ||
MX342851B (es) | Metodos y materiales para sintesis enzimatica de compuestos mogrosido. | |
MX2013005192A (es) | Cepa de pasteuria novedosa y usos de la misma. | |
UA116092C2 (uk) | Спосіб та композиція для боротьби з бур'янами (варіанти) | |
WO2012149058A3 (en) | Methods and system for interfering with viability of bacteria and related compounds and compositions | |
IN2012DN00939A (es) | ||
MY171760A (en) | Microorganisms and methods for the production of caprolactone | |
NZ709411A (en) | New bacteria and consortia for the reduction of amonia and/or methane emission in manure or soil | |
MX361288B (es) | Biocontrol de nematodos. | |
WO2011123576A3 (en) | Production of monoterpenes | |
WO2013009910A3 (en) | Eosinophil peroxidase compositions and methods of their use | |
IN2012DN03404A (es) | ||
MY168248A (en) | Next-instruction-type field | |
IN2014DN10762A (es) |