ME02621B - Method for the manufacturing of naltrexone - Google Patents

Method for the manufacturing of naltrexone

Info

Publication number: ME02621B
Authority: ME; Montenegro
Prior art keywords: naltrexone; manufacturing
Prior art date: 2010-11-05

Application number

MEP-2017-57A

Other languages

German (de)

French (fr)

Unknown language (me)

Inventor

Faveri Carla De

Florian Anton Martin Huber

Mariano Stivanello

Original Assignee

H Lundbeck As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-11-05

Filing date

2011-11-04

Publication date

2017-06-20

2011-11-04 Application filed by H Lundbeck As filed Critical H Lundbeck As

2017-06-20 Publication of ME02621B publication Critical patent/ME02621B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

MEP-2017-57A 2010-11-05 2011-11-04 Method for the manufacturing of naltrexone ME02621B (en)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US41040510P	2010-11-05	2010-11-05
DKPA201001007		2010-11-05
US201161489701P	2011-05-25	2011-05-25
DKPA201100396		2011-05-25
PCT/DK2011/000128 WO2012059103A1 (en)	2010-11-05	2011-11-04	Method for the manufacturing of naltrexone
EP11785301.0A EP2635586B1 (en)	2010-11-05	2011-11-04	Method for the manufacturing of naltrexone

Publications (1)

Publication Number	Publication Date
ME02621B true ME02621B (en)	2017-06-20

Family

ID=45001588

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MEP-2017-57A ME02621B (en)	2010-11-05	2011-11-04	Method for the manufacturing of naltrexone

Country Status (19)

Country	Link
EP (1)	EP2635586B1 (en)
JP (2)	JP6246589B2 (en)
AP (1)	AP3415A (en)
AU (1)	AU2011325563B2 (en)
CA (1)	CA2815093C (en)
CY (1)	CY1118742T1 (en)
DK (1)	DK2635586T3 (en)
EA (1)	EA022266B1 (en)
ES (1)	ES2620660T3 (en)
HR (1)	HRP20170379T1 (en)
HU (1)	HUE033596T2 (en)
LT (1)	LT2635586T (en)
ME (1)	ME02621B (en)
MX (1)	MX2013005009A (en)
PL (1)	PL2635586T3 (en)
PT (1)	PT2635586T (en)
RS (1)	RS55777B1 (en)
SI (1)	SI2635586T1 (en)
WO (1)	WO2012059103A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20140005217A1 (en)	2012-06-27	2014-01-02	H. Lundbeck A/S	Nalmefene for reduction of alcohol consumption in specific target populations
AR096851A1 (en)	2013-07-11	2016-02-03	H Lundbeck As	SALTS THAT DO NOT FORM HYDRATS OR SOLVATOS DE NALMEFENO
JP6448645B2 (en)	2013-12-20	2019-01-09	ハー・ルンドベック・アクチエゼルスカベット	Use of opioid receptor antagonists with kappa-activity and vortioxetine to treat depressive disorders with melancholic features
JP6797691B2 (en)	2014-04-22	2020-12-09	大塚製薬株式会社	A combination of blexiprazole and nalmefene and its use for the treatment of substance-related disorders
US9701687B2 (en) *	2014-05-05	2017-07-11	Noramco, Inc.	Process for the preparation of opioid compounds
US9701688B2 (en) *	2014-05-05	2017-07-11	Noramco, Inc.	Process for the preparation of opioid compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4535157A (en) *	1983-11-01	1985-08-13	Key Pharmaceuticals, Inc.	Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone
US4751307A (en)	1985-01-17	1988-06-14	Mallinckrodt, Inc.	Wittig-reaction processes
AU642447B2 (en) *	1989-10-16	1993-10-21	United States of America, as represented by the Secretary, U.S. Department of Commerce, The	Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via N-nor intermediates
FR2906252B1 (en) *	2006-09-21	2008-11-28	Sanofi Aventis Sa	PROCESS FOR THE PREPARATION OF NALTREXONE N-AKLYL HALIDES
WO2008138383A1 (en) *	2007-05-16	2008-11-20	Cilag Ag	Method for the production of n-methyl naltrexone bromide
ES2566559T3 (en) *	2008-09-30	2016-04-13	Mallinckrodt Llc	Processes for alkylation of secondary amino groups of morphinan derivatives
UA106752C2 (en)	2009-05-25	2014-10-10	Х. Луннбек А/С	producing nalmefene hydrochloride from naltrexone

2011
- 2011-11-04 PT PT117853010T patent/PT2635586T/en unknown
- 2011-11-04 EA EA201390658A patent/EA022266B1/en not_active IP Right Cessation
- 2011-11-04 EP EP11785301.0A patent/EP2635586B1/en active Active
- 2011-11-04 WO PCT/DK2011/000128 patent/WO2012059103A1/en active Application Filing
- 2011-11-04 LT LTEP11785301.0T patent/LT2635586T/en unknown
- 2011-11-04 AU AU2011325563A patent/AU2011325563B2/en not_active Ceased
- 2011-11-04 JP JP2013537002A patent/JP6246589B2/en active Active
- 2011-11-04 AP AP2013006897A patent/AP3415A/en active
- 2011-11-04 SI SI201131131A patent/SI2635586T1/en unknown
- 2011-11-04 ES ES11785301.0T patent/ES2620660T3/en active Active
- 2011-11-04 CA CA2815093A patent/CA2815093C/en active Active
- 2011-11-04 MX MX2013005009A patent/MX2013005009A/en active IP Right Grant
- 2011-11-04 HU HUE11785301A patent/HUE033596T2/en unknown
- 2011-11-04 DK DK11785301.0T patent/DK2635586T3/en active
- 2011-11-04 PL PL11785301T patent/PL2635586T3/en unknown
- 2011-11-04 RS RS20170244A patent/RS55777B1/en unknown
- 2011-11-04 ME MEP-2017-57A patent/ME02621B/en unknown
2016
- 2016-06-24 JP JP2016125389A patent/JP6215399B2/en active Active
2017
- 2017-03-07 HR HRP20170379TT patent/HRP20170379T1/en unknown
- 2017-03-17 CY CY20171100341T patent/CY1118742T1/en unknown

Also Published As

Publication number	Publication date
DK2635586T3 (en)	2017-03-27
LT2635586T (en)	2017-04-10
RS55777B1 (en)	2017-07-31
HRP20170379T1 (en)	2017-05-05
HUE033596T2 (en)	2017-12-28
SI2635586T1 (en)	2017-07-31
JP6246589B2 (en)	2017-12-13
CA2815093A1 (en)	2012-05-10
JP6215399B2 (en)	2017-10-18
CA2815093C (en)	2019-08-06
AU2011325563A1 (en)	2013-05-02
PL2635586T3 (en)	2017-06-30
WO2012059103A1 (en)	2012-05-10
AU2011325563B2 (en)	2015-08-20
AP3415A (en)	2015-09-30
EP2635586A1 (en)	2013-09-11
PT2635586T (en)	2017-03-30
EA022266B1 (en)	2015-11-30
MX2013005009A (en)	2013-08-01
JP2013541564A (en)	2013-11-14
EA201390658A1 (en)	2013-11-29
ES2620660T3 (en)	2017-06-29
JP2016199566A (en)	2016-12-01
AP2013006897A0 (en)	2013-05-31
CY1118742T1 (en)	2017-07-12
EP2635586B1 (en)	2017-02-08

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