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MA27661A1 - Indolone-oxazolidinones antibacteriennes, intermediaires pour leur preparation et compositions pharmaceutiques les contenant - Google Patents

Indolone-oxazolidinones antibacteriennes, intermediaires pour leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
MA27661A1
MA27661A1 MA28456A MA28456A MA27661A1 MA 27661 A1 MA27661 A1 MA 27661A1 MA 28456 A MA28456 A MA 28456A MA 28456 A MA28456 A MA 28456A MA 27661 A1 MA27661 A1 MA 27661A1
Authority
MA
Morocco
Prior art keywords
preparation
antibacterial
indolone
oxazolidinones
pharmaceutical compositions
Prior art date
Application number
MA28456A
Other languages
English (en)
Inventor
Toni-Jo Poel
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of MA27661A1 publication Critical patent/MA27661A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Indolone-oxazolidinones antibactériennes, intermédiaires pour leur préparation et compositions pharmaceutiques les contenant La présente invention propose des agents antibactériens de formule (I) et des intermédiaires pour leur préparation.
MA28456A 2003-02-24 2005-08-24 Indolone-oxazolidinones antibacteriennes, intermediaires pour leur preparation et compositions pharmaceutiques les contenant MA27661A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44973403P 2003-02-24 2003-02-24

Publications (1)

Publication Number Publication Date
MA27661A1 true MA27661A1 (fr) 2005-12-01

Family

ID=32908714

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28456A MA27661A1 (fr) 2003-02-24 2005-08-24 Indolone-oxazolidinones antibacteriennes, intermediaires pour leur preparation et compositions pharmaceutiques les contenant

Country Status (27)

Country Link
US (1) US7012088B2 (fr)
EP (1) EP1599470A1 (fr)
JP (1) JP3887396B2 (fr)
KR (1) KR100701226B1 (fr)
CN (1) CN100349892C (fr)
AP (1) AP2005003375A0 (fr)
AU (1) AU2004213246A1 (fr)
BR (1) BRPI0406824A (fr)
CA (1) CA2515984A1 (fr)
CO (1) CO5601039A2 (fr)
CR (1) CR7956A (fr)
EA (1) EA009725B1 (fr)
EC (1) ECSP055980A (fr)
GE (1) GEP20084306B (fr)
HK (1) HK1082253A1 (fr)
HR (1) HRP20050658A2 (fr)
IS (1) IS7883A (fr)
MA (1) MA27661A1 (fr)
MX (1) MXPA05008960A (fr)
NO (1) NO20052794L (fr)
OA (1) OA13032A (fr)
PL (1) PL377428A1 (fr)
RS (1) RS20050649A (fr)
TN (1) TNSN05202A1 (fr)
UA (1) UA80326C2 (fr)
WO (1) WO2004074282A1 (fr)
ZA (1) ZA200505225B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AP2007003904A0 (en) * 2004-08-06 2007-02-28 Pharmacia & Upjohn Co Llc Oxazolidinones containing oxindoles as antibacterial agents
CA2603943A1 (fr) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc Oxindole oxazolidinone utilise en tant qu'agent antibacterien
AU2006231919A1 (en) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
GEP20115364B (en) 2005-05-10 2011-12-26 Intermune Inc Method for modulation of stress-activated protein kinase system
WO2007088478A1 (fr) * 2006-02-01 2007-08-09 Pfizer Products Inc. Indazole oxazolidinones en tant qu'agents antibactériens
CA2637158A1 (fr) * 2006-02-08 2007-08-16 Pfizer Products Inc. Oxazolidinones contenant des oxindoles comme agents antibacteriens
EP2296653B1 (fr) 2008-06-03 2016-01-27 Intermune, Inc. Composés et procédés de traitement des troubles inflammatoires et fibrotiques
FR2948940B1 (fr) * 2009-08-04 2011-07-22 Servier Lab Nouveaux derives dihydroindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP5685384B2 (ja) * 2010-03-29 2015-03-18 公益財団法人相模中央化学研究所 ３，３−ジフルオロ−２，３−ジヒドロインドール−２−オン誘導体の製造方法
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
EP2910547B1 (fr) * 2012-10-17 2017-06-14 Okayama University Composé, tautomère et isomère géométrique de celui-ci, sel dudit composé, tautomère ou isomère géométrique, procédé de fabrication dudit composé, tautomère, isomère ou sel, ainsi qu'agent antimicrobien et médicament anti-infectieux
CN103193794B (zh) * 2013-04-12 2016-04-06 中国药科大学 一种异吲哚酮并异噁唑类稠环化合物及其合成方法
MX2016012808A (es) 2014-04-02 2017-01-05 Intermune Inc Piridinonas anti-fibroticas.
CN107151225B (zh) * 2017-06-30 2020-05-08 贵州大学 2-羟基吲哚类衍生物、其制备方法和用途
CN113773306B (zh) * 2021-10-29 2023-11-10 四川农业大学 3,3-二取代吲哚酮类化合物及其制备方法和应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
EP0359418B1 (fr) 1988-09-15 1994-10-12 The Upjohn Company 5-Indolinyl-5-bêta amidométhyloxazolidines-2-one, 3-(phényl condensé)-5 bêta amidométhyloxazolidines-2-ones et 3-phényl-azoté-5 bêta amidométhyloxazolidine 2-one
US5225565A (en) * 1988-09-15 1993-07-06 The Upjohn Company Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
HRP960159A2 (en) 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
DE19604223A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
DE19805117A1 (de) 1998-02-09 1999-08-12 Bayer Ag Neue Oxazolidinone mit azolhaltigen Tricyclen
HUP0103082A3 (en) 1998-06-05 2002-12-28 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
AU1045300A (en) 1998-11-17 2000-06-05 Bayer Aktiengesellschaft Novel heterocyclyl-substituted oxazolidone derivatives
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
PE20011124A1 (es) 2000-03-31 2001-10-28 Upjohn Co Nuevos agentes antibacterianos de benzosultam oxazolidinona
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
PE20030044A1 (es) 2000-11-17 2003-02-09 Upjohn Co Isoxazolinonas biciclicas de formula i
JP2005512975A (ja) 2001-10-25 2005-05-12 アストラゼネカ アクチボラグ 抗菌薬として有用なイソキサゾリン誘導体

Also Published As

Publication number Publication date
EA200501341A1 (ru) 2006-02-24
HRP20050658A2 (en) 2005-12-31
UA80326C2 (en) 2007-09-10
US7012088B2 (en) 2006-03-14
BRPI0406824A (pt) 2005-12-27
OA13032A (en) 2006-11-10
PL377428A1 (pl) 2006-02-06
NO20052794L (no) 2005-11-01
WO2004074282A1 (fr) 2004-09-02
AP2005003375A0 (en) 2005-09-30
JP2006515012A (ja) 2006-05-18
KR100701226B1 (ko) 2007-03-29
JP3887396B2 (ja) 2007-02-28
IS7883A (is) 2005-06-09
KR20050102135A (ko) 2005-10-25
US20040176610A1 (en) 2004-09-09
MXPA05008960A (es) 2005-11-04
EP1599470A1 (fr) 2005-11-30
NO20052794D0 (no) 2005-06-09
CR7956A (es) 2005-12-01
CO5601039A2 (es) 2006-01-31
GEP20084306B (en) 2008-02-11
AU2004213246A1 (en) 2004-09-02
RS20050649A (en) 2007-11-15
CA2515984A1 (fr) 2004-09-02
ECSP055980A (es) 2006-01-16
CN1742008A (zh) 2006-03-01
TNSN05202A1 (fr) 2007-06-11
CN100349892C (zh) 2007-11-21
EA009725B1 (ru) 2008-02-28
HK1082253A1 (en) 2006-06-02
ZA200505225B (en) 2006-11-29

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