Yi et al., 2022 - Google Patents
Transforming “cold” tumors into “hot” ones via tumor-microenvironment-responsive siRNA micelleplexes for enhanced immunotherapyYi et al., 2022
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- 3595600040767848588
- Author
- Yi Y
- Yu M
- Feng C
- Hao H
- Zeng W
- Lin C
- Chen H
- Lv F
- Zhu D
- Ji X
- Mei L
- Wu M
- Tao W
- Publication year
- Publication venue
- Matter
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It is highly desirable to turn" cold" tumors into" hot" ones to improve the efficacy of antitumor immunotherapy. Herein, we develop the peptide-based small interfering RNA (siRNA) micelleplexes (P A7R@ siPD-L1) for normalizing vascular-immune crosstalk to establish a …
- 206010028980 Neoplasm 0 title abstract description 116
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- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
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