Nothing Special   »   [go: up one dir, main page]

Gnana-Prakasam et al., 2009 - Google Patents

Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection

Gnana-Prakasam et al., 2009

View PDF
Document ID
3488324535253471636
Author
Gnana-Prakasam J
Zhang M
Martin P
Atherton S
Smith S
Ganapathy V
Publication year
Publication venue
Biochemical Journal

External Links

Snippet

Haemochromatosis is a genetic disorder of iron overload resulting from loss-of-function mutations in genes coding for the iron-regulatory proteins HFE [H LA-like protein involved in iron (Fe) homoeostasis], transferrin receptor 2, ferroportin, hepcidin and HJV (haemojuvelin) …
Continue reading at drive.google.com (PDF) (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00

Similar Documents

Publication Publication Date Title
Dalmau et al. Autoantibodies to synaptic receptors and neuronal cell surface proteins in autoimmune diseases of the central nervous system
Yang et al. Silencing Nogo‐A promotes functional recovery in demyelinating disease
Basu et al. Connexin 43/47 channels are important for astrocyte/oligodendrocyte cross-talk in myelination and demyelination
Philp et al. Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse
Rodriguez et al. Immunoglobulins reactive with myelin basic protein promote CNS remyelination
Gourdain et al. Exacerbation of experimental autoimmune encephalomyelitis in prion protein (PrPc)-null mice: evidence for a critical role of the central nervous system
US8324182B2 (en) Humanized model of membrane attack complex (MAC) formation on murine retina and compositions, kits and methods for treatment of macular degeneration
US20080233132A1 (en) Multiple sclerosis therapy
Ishii et al. Mitochondrial C3a receptor activation in oxidatively stressed epithelial cells reduces mitochondrial respiration and metabolism
Busch et al. Anaphylatoxins activate Ca2+, Akt/PI3-kinase, and FOXO1/FoxP3 in the retinal pigment epithelium
Voynova et al. Correction of autophagy impairment inhibits pathology in the NOD. H-2h4 mouse model of primary Sjögren's syndrome
Huo et al. Upregulation of TRPC5 in hippocampal excitatory synapses improves memory impairment associated with neuroinflammation in microglia knockout IL-10 mice
Gnana-Prakasam et al. Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection
Harris et al. Phosphacan and receptor protein tyrosine phosphatase β expression mediates deafferentation‐induced synaptogenesis
US7553484B2 (en) Modulating neuronal outgrowth via the major histocompatibility complex class I (MHC I) molecule
US10874712B2 (en) Methods, compounds and compositions for modulating blood brain barrier integrity and re-myelination
US11338019B2 (en) Recombinant thrombomodulin domain 1 for use in treating eye diseases associated with pathological ocular angiogenesis
KR102534242B1 (en) Method of identifying IFN-γ regulating agent targeting Klra5 protein and medicament comprising the agent
WO2011105527A1 (en) Nerve growth promoter
Cao Targeted treatment approaches and pathogenicity of antibody subclasses in MuSK-myasthenia gravis
US20090324612A1 (en) Modulating neuronal outgrowth via the major histocompatibility complex class i (mhc i) molecule
Trolese Targeting motor neuron-immune system crosstalk to modulate the disease progression in Amyotrophic Lateral Sclerosis mouse model
Zloh et al. Visual stimulation and brain-derived neurotrophic factor (BDNF) have protective effects in experimental autoimmune uveoretinitis
Char et al. Rufy3 regulates anti-bacterial responses by controlling endolysosomes perinuclear positioning in activated phagocytes.
Zhu et al. GMFB/AKT/TGF‐β3 in Müller cells mediated early retinal degeneration in a streptozotocin‐induced rat diabetes model