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Yang et al., 2022 - Google Patents

Ligand-switchable nanoparticles resembling viral surface for sequential drug delivery and improved oral insulin therapy

Yang et al., 2022

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Document ID
15638443194420875437
Author
Yang T
Wang A
Nie D
Fan W
Jiang X
Yu M
Guo S
Zhu C
Wei G
Gan Y
Publication year
Publication venue
Nature Communications

External Links

Snippet

Mutual interference between surface ligands on multifunctional nanoparticles remains a significant obstacle to achieving optimal drug-delivery efficacy. Here, we develop ligand- switchable nanoparticles which resemble viral unique surfaces, enabling them to fully …
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
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