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Chen et al., 2014 - Google Patents

Dysregulation of the miR-324-5p-CUEDC2 axis leads to macrophage dysfunction and is associated with colon cancer

Chen et al., 2014

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Document ID
13073610533246884666
Author
Chen Y
Wang S
Mu R
Luo X
Liu Z
Liang B
Zhuo H
Hao X
Wang Q
Fang D
Bai Z
Wang Q
Wang H
Jin B
Gong W
Zhou T
Zhang X
Xia Q
Li T
Publication year
Publication venue
Cell reports

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Summary CUEDC2, a CUE-domain-containing protein, modulates inflammation, but its involvement in tumorigenesis is still poorly understood. Here, we report that CUEDC2 is a key regulator of macrophage function and critical for protection against colitis-associated …
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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