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Guerin et al., 2024 - Google Patents

Temporally discordant chromatin accessibility and DNA demethylation define short and long-term enhancer regulation during cell fate specification

Guerin et al., 2024

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Document ID
8033576388150829544
Author
Guerin L
Scott T
Yap J
Johansson A
Puddu F
Charlesworth T
Yang Y
Simmons A
Lau K
Ihrie R
Hodges E
Publication year
Publication venue
bioRxiv

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Snippet

Epigenetic mechanisms govern the transcriptional activity of lineage-specifying enhancers; but recent work challenges the dogma that joint chromatin accessibility and DNA demethylation are prerequisites for transcription. To understand this paradox, we …
Continue reading at pmc.ncbi.nlm.nih.gov (HTML) (other versions)

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