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Mathijssen et al., 2002 - Google Patents

Pharmacology of topoisomerase I inhibitors irinotecan (CPT-11) and topotecan

Mathijssen et al., 2002

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Document ID
8017301690212483703
Author
Mathijssen R
Loos W
Verweij J
Sparreboom A
Publication year
Publication venue
Current cancer drug targets

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Topotecan and irinotecan (CPT-11) are both anticancer agents active in the inhibition of topoisomerase I, an enzyme involved in DNA replication and RNA transcription. During the last decades, an immense amount of research into this class of anticancer agents has been …
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