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Chen, 2022 - Google Patents

A Cancer Proliferation Gene Signature Supervised by Ki-67 Strata Specific to Luminal A, Estrogen Receptor-Positive, and HER2-Negative Ductal Carcinomas

Chen, 2022

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Document ID
7610728340897904598
Author
Chen Y
Publication year
Publication venue
Medical Research Archives

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Snippet

Clinically determined Ki-67 is a well-established marker for assessing proliferation potential in breast and other cancers. However, Ki-67 and the recommended thresholds for clinical decision-making vary systematically across breast cancer subtypes. In this study, an …
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    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/574—Immunoassay; Biospecific binding assay for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Hybridisation probes
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    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
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    • C12Q2600/00—Oligonucleotides characterized by their use
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