Nothing Special   »   [go: up one dir, main page]

Yamauchi et al., 2008 - Google Patents

Electrochemical carboxylation of α, α-difluorotoluene derivatives and its application to the synthesis of α-fluorinated nonsteroidal anti-inflammatory drugs

Yamauchi et al., 2008

Document ID
6018085649402228637
Author
Yamauchi Y
Fukuhara T
Hara S
Senboku H
Publication year
Publication venue
Synlett

External Links

Snippet

Electrochemical carboxylation of α, α-difluorotoluene derivatives resulted in an efficient fixation of carbon dioxide to give the corresponding α-fluorophenylacetic acids in good yields, and this reaction was successfully applied to the synthesis of α-fluorinated …
Continue reading at www.thieme-connect.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2101/00—Systems containing only non-condensed rings
    • C07C2101/12—Systems containing only non-condensed rings with a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/04—Electrolytic production of organic compounds by reduction

Similar Documents

Publication Publication Date Title
Yamauchi et al. Electrochemical carboxylation of α, α-difluorotoluene derivatives and its application to the synthesis of α-fluorinated nonsteroidal anti-inflammatory drugs
Li et al. Bridging plastic recycling and organic catalysis: photocatalytic deconstruction of polystyrene via a C–H oxidation pathway
Zhang et al. Lewis acid catalyzed highly selective halogenation of aromatic compounds
Bloom et al. Site‐Selective Approach to β‐Fluorination: Photocatalyzed Ring Opening of Cyclopropanols
Xiao et al. Friedel-Crafts acylation reactions in pyridinium based ionic liquids
Mitsudo et al. Pd/TEMPO-catalyzed electrooxidative synthesis of biaryls from arylboronic acids or arylboronic esters
Wu et al. Electrocatalytic oxidative cleavage of electron-deficient substituted stilbenes in acetonitrile− water employing a new high oxidation potential electrocatalyst. An electrochemical equivalent of ozonolysis
Hara et al. Electrochemical fluorination of β-dicarbonyl compounds using p-iodotoluene difluoride as a mediator
Tommasino et al. Trifluoromethylation reactions with potassium trifluoromethanesulfinate under electrochemical oxidation
Senboku et al. Efficient synthesis of mandel acetates by electrochemical carboxylation of benzal diacetates
Yuan et al. Highly site-selective formation of perfluoroalkylated anilids via a protecting strategy by molybdenum hexacarbonyl catalyst
Hossain et al. Learning from vitamin B12‐mediated reactions: cobalt (III)− carbon‐assisted catalytic C− H difluoroacylation of (Hetero) arenes through controlled‐potential electrolysis
Kooli et al. Electrochemical Hydroxylation of Electron‐Rich Arenes in Continuous Flow
Bosco et al. Redox‐mediated oxidation of alcohols using Cl−/OCl− redox couple in biphasic media
Chiba et al. Benzylic intermolecular carbon− carbon bond formation by selective anodic oxidation of dithioacetals
Zucchi et al. Cobalt-catalyzed carbonylation of benzyl halides using polyethylene glycols as phase-transfer catalysts
CN108441883A (en) A kind of method that electrochemical fluorination prepares perfluor methyl isobutyrate
Srihari et al. Iodine-catalyzed nucleophilic substitution reactions of benzylic alcohols
Akane et al. Generation and reaction of samarium (II) Iodide Equivalent from Samarium and Chlorotrimethylsilane/Sodium Iodide System in Acetonitrile.
Cao et al. Electrochemical partial fluorination of organic compounds. 80. Synthesis of cyclic α-arylthio-α-monofluorophosphonate esters
Suzuki et al. Ozone-mediated nitration of phenylalkyl ethers, phenylacetic esters, and related compounds with nitrogen dioxide. The highest ortho substitution observed in the electrophilic nitration of arenes
Yamauchi et al. Synthesis of 2-aryl-2, 3, 3, 3-tetrafluoropropanoic Acids, tetrafluorinated fenoprofen and ketoprofen by electrochemical carboxylation of pentafluoroethylarenes
Purgato et al. Electrocatalytic oxidation of alcohols, diols and arenes with ceric p-methoxybenzenesulfonate and ceric p-toluenesulfonate
Tanaka et al. Electrooxidation of alcohols in a disperse system with N-oxyl-immobilized polyethylene particles as disperse phase and aqueous NaHCO3/NaBr as disperse media: A totally closed electrolysis system
Cognet et al. Application of ultrasound technology to electroorganic synthesis: Reduction of acetophenone