Nothing Special   »   [go: up one dir, main page]

Nachman et al., 1970 - Google Patents

Increased vascular permeability produced by human platelet granule cationic extract

Nachman et al., 1970

View PDF
Document ID
5956744955894251813
Author
Nachman R
Weksler B
Ferris B
et al.
Publication year
Publication venue
The Journal of Clinical Investigation

External Links

Snippet

A cationic protein extract obtained from isolated human platelet granules increased vascular permeability in mouse and rabbit skin. The permeability-enhancing effect was not inhibited by soybean trypsin and pancreatic trypsin inhibitor, methylsergide maleate …
Continue reading at www.jci.org (PDF) (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

Similar Documents

Publication Publication Date Title
Nachman et al. Increased vascular permeability produced by human platelet granule cationic extract
Colucci et al. Generation in plasma of a fast-acting inhibitor of plasminogen activator in response to endotoxin stimulation.
Sueishi et al. Permeability enhancing and chemotactic activities of lower molecular weight degradation products of human fibrinogen
Ziff et al. Effect of leukocyte and synovial membrane extracts on cartilage mucoprotein
Rijken et al. Relationship between tissue plasminogen activator and the activators in blood and vascular wall
Ratnoff et al. The inhibition of plasmin, plasma kallikrein, plasma permeability factor, and the C'1r subcomponent of the first component of complement by serum C'1 esterase inhibitor
Colvin et al. Fibrinogen/fibrin on the surface of macrophages: detection, distribution, binding requirements, and possible role in macrophage adherence phenomena.
Stecher et al. The chemotactic activity of fibrin lysis products
Krishnamurti et al. Plasminogen activator inhibitor: a regulator of ancrod-induced fibrin deposition in rabbits
Tambourgi et al. Pro‐inflammatory activities in elapid snake venoms
Taylor Jr et al. Whole blood clot lysis: in vitro modulation by activated protein C
Gurewich et al. The resistance of fibrinogen and soluble fibrin monomer in blood to degradation by a potent plasminogen activator derived from cadaver limbs
Warkentin et al. Symmetrical peripheral gangrene in critical illness
Rifkin Trypanosoma brucei: some properties of the cytotoxic reaction induced by normal human serum
Kowalski et al. Circulating fibrinogen degradation products (FDP) in dog blood after intravenous thrombin infusion
Aoki et al. Inactivation of human serum plasminogen antiactivator by synthetic fibrinolysis inducers
Goldstein et al. Effects of bacterial endotoxin on the fibrinolytic activity of normal human leukocytes
Semar et al. Partial purification and properties of a plasminogen activator from human erythrocytes
Damus et al. A purified procoagulant enzyme from the venom of the eastern diamondback rattlesnake (Crotalus adamanteus): In vivo and in vitro studies
Ali et al. Purification of rabbit kidney cytokinase and a comparison of its properties with human urokinase
Dodds et al. The effect of cobra venom factor on hemostasis in guinea pigs
Beller et al. Disseminated intravascular coagulation in pregnancy
WO1993011151A1 (en) ALBOAGGREGINS: PLATELET AGONISTS WHICH BIND TO PLATELET MEMBRANE GLYCOPROTEIN Ib
Glas-Greenwalt et al. Ancrod: normalization of fibrinolytic enzyme abnormalities in patients with systemic lupus erythematosus and lupus nephritis
Conn et al. Coagulation abnormalities in rheumatoid disease