Vezeridis et al., 1990 - Google Patents
Heterogeneity of potential for hematogenous metastasis in a human pancreatic carcinomaVezeridis et al., 1990
- Document ID
- 5612294555604224990
- Author
- Vezeridis M
- Meitner P
- Tibbetts L
- Doremus C
- Tzanakakis G
- Calabresi P
- Publication year
- Publication venue
- Journal of Surgical Research
External Links
Snippet
Human pancreatic carcinoma, a disease with grave prognosis, frequently metastasizes to the liver, with detrimental consequences for the host. Good models of experimental metastasis for this disease are lacking. We describe a model of hepatic metastasis from the …
- 206010027476 Metastasis 0 title abstract description 31
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1203—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules in a form not provided for by groups A61K51/1206 - A61K51/1296, e.g. cells, cell fragments, viruses, virus capsides, ghosts, red blood cells, viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Micro-organisms or materials therefrom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Naito et al. | Different growth pattern and biologic behavior of human renal cell carcinoma implanted into different organs of nude mice | |
Giavazzi et al. | Experimental nude mouse model of human colorectal cancer liver metastases | |
Fidler | Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis | |
Price et al. | Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice | |
Miner et al. | Clonal drift of cell surface, melanogenic, and experimental metastatic properties of in vivo-selected, brain meninges-colonizing murine B16 melanoma | |
Whitehead et al. | A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer | |
Momose et al. | Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas | |
Manzotti et al. | Importance of orthotopic implantation for human tumors as model systems: relevance to metastasis and invasion | |
Talmadge et al. | Macrophage content of metastatic and nonmetastatic rodent neoplasms. | |
Kawashiri et al. | Development of a new invasion and metastasis model of human oral squamous cell carcinomas | |
Vezeridis et al. | Heterogeneity of potential for hematogenous metastasis in a human pancreatic carcinoma | |
Price et al. | Studies of human breast cancer metastasis using nude mice | |
Yang et al. | A reproducible rat liver cancer model for experimental therapy: introducing a technique of intrahepatic tumor implantation | |
Bouvet et al. | Chronologically-specific metastatic targeting of human pancreatic tumors in orthotopic models | |
An et al. | Development of a high metastatic orthotopic model of human renal cell carcinoma in nude mice: benefits of fragment implantation compared to cell-suspension injection | |
Blumer et al. | Hepatocellular carcinoma xenografts established from needle biopsies preserve the characteristics of the originating tumors | |
Shevrin et al. | Patterns of metastasis by the human prostate cancer cell line PC‐3 in athymic nude mice | |
Vezeridis et al. | In vivo selection of a highly metastatic cell line from a human pancreatic carcinoma in the nude mouse | |
Naito et al. | In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice | |
Pollack et al. | Use of young nude mice for selection of subpopulations of cells with increased metastatic potential from nonsyngeneic neoplasms | |
Wang et al. | A novel, clinically relevant animal model of metastatic pancreatic adenocarcinoma biology and therapy | |
Bailey et al. | Human breast-cancer xenografts in immune-suppressed mice | |
He et al. | Progressive epithelial to mesenchymal transitions in ARCaPE prostate cancer cells during xenograft tumor formation and metastasis | |
Huysentruyt et al. | Influence of methotrexate and cisplatin on tumor progression and survival in the VM mouse model of systemic metastatic cancer | |
Schittek et al. | Growth of pulmonary metastases of B16 melanoma in mast cell-free mice |