Nothing Special   »   [go: up one dir, main page]

Holm et al., 2016 - Google Patents

Simplifying microfluidic separation devices towards field-detection of blood parasites

Holm et al., 2016

View HTML
Document ID
4832241856700456349
Author
Holm S
Beech J
Barrett M
Tegenfeldt J
Publication year
Publication venue
Analytical Methods

External Links

Snippet

With our sights set on a simple and inexpensive diagnostics device based on extraction and enrichment of parasites from human blood, we present a device design that relies on a combination of multiple different deterministic lateral displacement arrays. Our end goal is a …
Continue reading at pubs.rsc.org (HTML) (other versions)

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated micro-fluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated micro-fluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated micro-fluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated micro-fluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated micro-fluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure

Similar Documents

Publication Publication Date Title
Holm et al. Simplifying microfluidic separation devices towards field-detection of blood parasites
Holm et al. Separation of parasites from human blood using deterministic lateral displacement
CN109456875B (en) Rare cell multi-stage sorting microfluidic device integrating inertia and deterministic lateral displacement technology
Li et al. Continuous-flow microfluidic blood cell sorting for unprocessed whole blood using surface-micromachined microfiltration membranes
EP2616551B1 (en) Method for isolating cells from heterogeneous solution using microfluidic trapping vortices
US9808803B2 (en) Systems and methods for particle focusing in microchannels
CN107702973B (en) Whole blood plasma separation system and method
EP3902630B1 (en) Multi-dimensional double spiral device and methods of use thereof
Kim et al. A high-efficiency microfluidic device for size-selective trapping and sorting
CN111744565B (en) Microfluidic device and system for multi-channel parallel detection of cell deformability
CN105907633A (en) Micro-fluidic chip device used for fine sorting, counting and detection of cell
KR101824080B1 (en) Microfluidic device for high-throughput, high-efficiency microparticle separation using non-Newtonian fluid
CN111647499A (en) Cell multistage sorting micro-fluidic chip integrating viscoelasticity and magnetic force
Geng et al. Multi-component continuous separation chip composed of micropillar arrays in a split-level spiral channel
Tegenfeldt Analytical Methods
US20160184822A1 (en) Microfluidic device for particle enumeration
Feng et al. Multiple-streams focusing-based cell separation in high viscoelasticity flow
CN111690534B (en) Tumor cell multistage sorting device based on viscoelastic focusing technology
Tseng et al. High-throughput white blood cells (leukocytes) separation and enrichment from whole blood by hydrodynamic and inertial force
CN114870913A (en) Micro-fluidic device and system integrating elasticity-inertial focusing and virtual flow channel
CN117126722A (en) Cell detection chip, system and method integrating viscoelastic sorting
Wei Microfluidic approaches for diseased cell separation from blood
Beech et al. Morphology-based sorting-blood cells and parasites
GUOFENG Microfluidics for Size and Deformability Based Cell Sorting