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Zhang et al., 2017 - Google Patents

SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis

Zhang et al., 2017

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Document ID
4621611963571000573
Author
Zhang Y
Xie L
Gunasekar S
Tong D
Mishra A
Gibson W
Wang C
Fidler T
Marthaler B
Klingelhutz A
Abel E
Samuel I
Smith J
Cao L
Sah R
Publication year
Publication venue
Nature cell biology

External Links

Snippet

Adipocytes undergo considerable volumetric expansion in the setting of obesity. It has been proposed that such marked increases in adipocyte size may be sensed via adipocyte- autonomous mechanisms to mediate size-dependent intracellular signalling. Here, we show …
Continue reading at www.ncbi.nlm.nih.gov (HTML) (other versions)

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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
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    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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