Marc Courtemanche, Rafael J. Ramirez, and Stanley Nattel. Ionic mechanisms underlying human atrial action potential properties insights from a mathematical model Am J Physiol Heart Circ Physiol 1998 275: H301-H321. The implementation of this model in NEURON was contributed by Ingemar Jacobson.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Cardiac atrial cell; Heart cell

Currents: I Na,t; I L high threshold; I K; I Sodium; I Calcium; I Potassium; Na/Ca exchanger

Genes: Kv4.3 KCND3; Kv1.5 KCNA5; HERG KCNH2

Model Concept(s): Ion Channel Kinetics; Action Potentials; Heart disease; Calcium dynamics

Simulation Environment: NEURON

Implementer(s): Jacobson, Ingemar [Ingemar.Jacobson at astrazeneca.com]

References:

Courtemanche M, Ramirez RJ, Nattel S. (1998). Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model. The American journal of physiology. 275 [PubMed]