Model files from the paper: M. Migliore, E. Cook, D.B. Jaffe, D.A. Turner and D. Johnston, Computer simulations of morphologically reconstructed CA3 hippocampal neurons, J. Neurophysiol. 73, 1157-1168 (1995). Demonstrates how the same cell could be bursting or non bursting according to the Ca-independent conductance densities. Includes calculation of intracellular Calcium. Instructions are provided in the below README file. Contact michele.migliore@pa.ibf.cnr.it if you have any questions about the implementation of the model.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Hippocampus CA3 pyramidal GLU cell

Currents: I Na,t; I L high threshold; I N; I T low threshold; I A; I K; I M; I K,Ca; I Calcium

Model Concept(s): Bursting; Detailed Neuronal Models; Synaptic Integration

Simulation Environment: NEURON

Implementer(s): Migliore, Michele [Michele.Migliore at Yale.edu]

References:

Migliore M, Cook EP, Jaffe DB, Turner DA, Johnston D. (1995). Computer simulations of morphologically reconstructed CA3 hippocampal neurons. Journal of neurophysiology. 73 [PubMed]