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A model of rodent mechanoreceptors (LTMRs) (Medlock et al., 2024)

"... unlike the dichotomous frequency preference characteristic of RA1 and RA2/Pacinian afferents in other species, rodent RAs fell along a continuum. Fitting generalized linear models (GLMs) to experimental data reproduced the reliability and precision of rodent RAs. The resulting model parameters highlight key mechanistic differences across the RA spectrum; specifically, the integration window of different RAs transitions from wide to narrow as tuning preferences across the population move from low to high frequencies..."

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s):

Cell Type(s):

Currents:

Receptors:

Genes:

Transmitters:

Model Concept(s): Touch

Simulation Environment: MATLAB

Implementer(s): Medlock, Laura [laura.medlock at mail.utoronto.ca]

References:

Medlock L et al. (2024). Encoding of vibrotactile stimuli by mechanoreceptors in rodent glabrous skin. The Journal of neuroscience : the official journal of the Society for Neuroscience. [PubMed]


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