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It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.
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Table of contents (17 chapters)
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Bibliographic Information
Book Title: Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis
Editors: George G. Harrigan, Royston Goodacre
DOI: https://doi.org/10.1007/978-1-4615-0333-0
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 2003
Hardcover ISBN: 978-1-4020-7370-0Published: 31 January 2003
Softcover ISBN: 978-1-4613-5025-5Published: 23 October 2012
eBook ISBN: 978-1-4615-0333-0Published: 06 December 2012
Edition Number: 1
Number of Pages: XIV, 335