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Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis

  • Textbook
  • © 2003

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About this book

It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.

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Keywords

Table of contents (17 chapters)

Editors and Affiliations

  • Pharmacia Corporation, Chesterfield, USA

    George G. Harrigan

  • Department of Chemistry, UMIST, Manchester, UK

    Royston Goodacre

Bibliographic Information

  • Book Title: Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis

  • Editors: George G. Harrigan, Royston Goodacre

  • DOI: https://doi.org/10.1007/978-1-4615-0333-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2003

  • Hardcover ISBN: 978-1-4020-7370-0Published: 31 January 2003

  • Softcover ISBN: 978-1-4613-5025-5Published: 23 October 2012

  • eBook ISBN: 978-1-4615-0333-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIV, 335

  • Topics: Biochemistry, general, Analytical Chemistry

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