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| Verfasst von: | Dietrich, Maximilian [VerfasserIn]  |
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| | Antonovici, Ana [VerfasserIn] |
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| | Hölle, Tobias [VerfasserIn] |
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| | Nußhag, Christian [VerfasserIn] |
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| | Kapp, Anne-Christine [VerfasserIn] |
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| | Studier-Fischer, Alexander [VerfasserIn] |
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| | Arif, Rawa [VerfasserIn] |
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| | Nickel, Felix [VerfasserIn] |
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| | Weigand, Markus A. [VerfasserIn] |
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| | Frey, Norbert [VerfasserIn] |
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| | Lichtenstern, Christoph [VerfasserIn] |
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| | Leuschner, Florian [VerfasserIn] |
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| | Fischer, Dania [VerfasserIn] |
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| Titel: | Microcirculatory tissue oxygenation correlates with kidney function after transcatheter aortic valve implantation-Results from a prospective observational study |
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| Verf.angabe: | Maximilian Dietrich, Ana Antonovici, Tobias Hölle, Christian Nusshag, Anne-Christine Kapp, Alexander Studier-Fischer, Rawa Arif, Felix Nickel, Markus Alexander Weigand, Norbert Frey, Christoph Lichtenstern, Florian Leuschner and Dania Fischer |
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| E-Jahr: | 2023 |
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| Jahr: | 14 February 2023 |
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| Umfang: | 13 S. |
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| Fussnoten: | Gesehen am 24.03.2023 |
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| Titel Quelle: | Enthalten in: Frontiers in Cardiovascular Medicine |
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| Ort Quelle: | Lausanne : Frontiers Media, 2014 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 10(2023) vom: Feb., Artikel-ID 1108256, Seite 1-13 |
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| ISSN Quelle: | 2297-055X |
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| Abstract: | IntroductionKidney dysfunction is common in patients with aortic stenosis (AS) and correction of the aortic valve by transcatheter aortic valve implantation (TAVI) often affects kidney function. This may be due to microcirculatory changes.MethodsWe evaluated skin microcirculation with a hyperspectral imaging (HSI) system, and compared tissue oxygenation (StO2), near-infrared perfusion index (NIR), tissue hemoglobin index (THI) and tissue water index (TWI) in 40 patients undergoing TAVI versus 20 control patients. HSI parameters were measured before TAVI (t1), directly after TAVI (t2), and on postinterventional day 3 (t3). The primary outcome was the correlation of tissue oxygenation (StO2) to the creatinine level after TAVI.ResultsWe performed 116 HSI image recordings in patients undergoing TAVI for the treatment of severe aortic stenosis and 20 HSI image recordings in control patients. Patients with AS had a lower THI at the palm (p = 0.034) and a higher TWI at the fingertips (p = 0.003) in comparison to control patients. TAVI led to an increase of TWI, but had no uniform enduring effect on StO2 and THI. Tissue oxygenation StO2 at both measurement sites correlated negatively with creatinine levels after TAVI at t2 (palm: ρ = −0.415; p = 0.009; fingertip: ρ = −0.519; p < 0.001) and t3 (palm: ρ = −0.427; p = 0.008; fingertip: ρ = −0.398; p = 0.013). Patients with higher THI at t3 reported higher physical capacity and general health scores 120 days after TAVI.ConclusionHSI is a promising technique for periinterventional monitoring of tissue oxygenation and microcirculatory perfusion quality, which are related to kidney function, physical capacity, and clinical outcomes after TAVI.Clinical trial registrationhttps://drks.de/search/de/trial, identifier DRKS00024765. |
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| DOI: | doi:10.3389/fcvm.2023.1108256 |
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| URL: | kostenfrei: Volltext: https://doi.org/10.3389/fcvm.2023.1108256 |
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| | kostenfrei: Volltext: https://www.frontiersin.org/articles/10.3389/fcvm.2023.1108256 |
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| | DOI: https://doi.org/10.3389/fcvm.2023.1108256 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1840028874 |
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| Verknüpfungen: | → Zeitschrift |
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| Lokale URL UB: |  Zum Volltext |
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Microcirculatory tissue oxygenation correlates with kidney function after transcatheter aortic valve implantation-Results from a prospective observational study / Dietrich, Maximilian [VerfasserIn]; 14 February 2023 (Online-Ressource)