Papers by Uriel Halbreich
Academia Mental Health and Well-Being, Sep 30, 2024
Abstract Conflicts in various international regions underscore controversies and divisions in th... more Abstract Conflicts in various international regions underscore controversies and divisions in the United States and Europe , especially when images of destruction penetrate homes through mass media.they disrupt attention from localized and/or culturally-sensitive ongoing issues oof well-being. Domestic natural and man-made disasters profoundly impact physical and mental health of communities and individuals. Often opposing conflicting interests and predetermined bias overshadow the discourse. However, In many cases emphasis on common grounds and similarities would facilitate pursuit of coordinated preventative, immediate as well as aftermath mental health interventions which are essential.
Bookmarks Related papers MentionsView impact
Our World is changing at an accelerated pace. We are witnessing tumultuous situations and uncerta... more Our World is changing at an accelerated pace. We are witnessing tumultuous situations and uncertain futures. This is a timely opportunity to depart from inertia and embark on new initiatives, to strive to repair the world. With our new journal: Academia Mental Health and Well-Being, our achievable ambition is to contribute to:The Well-Being of All Beings, whoever and wherever they are. The pursuit of this ideal and turning it into a reality requires us to promote broad dissemination of knowledge, face challenges with an open mind, embrace multilogues and acceptance of diverse ideas, expressions and experiences – even, and especially – if they disagree with our views. We hope to express multiple ideas and opinions with civility and advocate for actions with compassion, understanding and productive non-violence.Our research-communications and endeavors should learn from the past, respect thinkers and healers of all cultures, consider the present and be future-oriented. We should cautiously consider short-term (Y2030) and long-term (Y2050) predictions and promote the adaptation of practice and attitudes. We should encourage initiatives that take risks for innovation. Especially for trainees, it is intriguing to instill an attitude of ‘strive to know what you do not know’ and the ability to adapt to technologies that are not yet fathomable.Together – with our resourceful and dynamic Publisher: Academia.edu – we envision that each published idea and project will be like a pebble thrown into calm water initiating expanding circles of waves, strengthening Academic research and teaching, exploding beyond the ivory towers of academia – to be implemented in operational day-to-day Mental and Physical Health, preventing disorders and impacting treatments when needed, further expanding the circle of operational knowledge to the wider real-world of Well-Being, socio-economic ramifications and Life in all its complex dimensions.
Bookmarks Related papers MentionsView impact
The Lancet, Feb 1, 1980
Bookmarks Related papers MentionsView impact
PubMed, Oct 1, 1982
Bookmarks Related papers MentionsView impact
Psychoneuroendocrinology, 1981
Bookmarks Related papers MentionsView impact
PubMed, 1984
Bookmarks Related papers MentionsView impact
Psychiatric Clinics of North America, Aug 1, 1980
Bookmarks Related papers MentionsView impact
The Journal of Clinical Psychiatry, Aug 15, 2004
A continuation study of an extract of St. John&am... more A continuation study of an extract of St. John's wort (Hypericum perforatum) for depression was performed in follow-up to an acute study that found no significant difference between St. John's wort extract and placebo. Seventeen subjects with DSM-IV-defined major depressive disorder who responded to St. John's wort extract in the acute-phase study (phase 1) were continued on double-blind treatment with the same preparation for 24 weeks. Ninety-five subjects who did not respond to either St.…
Bookmarks Related papers MentionsView impact
American Journal of Psychiatry, Mar 1, 1997
Bookmarks Related papers MentionsView impact
Advances in Psychiatry, 2018
The Republic of Georgia (Sakartvelo in Georgia) is a relatively small country of 69,700 square ki... more The Republic of Georgia (Sakartvelo in Georgia) is a relatively small country of 69,700 square kilometers and only 3.8 million people. Being in the Southern Caucasus on the crossroads between Eastern Europe and Western Asia, it has been experiencing a tumultuous history for over 3000 years. It was subject to many invasions by stronger neighbors and maintained independence only for short periods in between. It was annexed by Tsarist Russia in 1800 and became a Soviet Republic, part of the Soviet Union (USSR) in 1921.
Bookmarks Related papers MentionsView impact
American Journal of Psychiatry, 1994
Clinical features, assessment, and differential diagnosis of multiple sclerosis. Depression and a... more Clinical features, assessment, and differential diagnosis of multiple sclerosis. Depression and affective disorders in multiple sclerosis. Cognitive and neuroimaging changes in multiple sclerosis. Role of genetic factors for the autoimmune pathogenesis of multiple sclerosis. Current treatment strategies and perspectives of multiple sclerosis. Psychosomatic-somatopsychic aspects of multiple sclerosis. Disability and rehabilitation. Patients advocacy groups and support associations in multiple sclerosis: the National Multiple Sclerosis Society. Multiple sclerosis: a neurostructural model of affective and cognitive disorders. Index.
Bookmarks Related papers MentionsView impact
Psychopharmacology bulletin, 1997
The enzyme monoamine oxidase (MAO) has generated considerable interest as a biological marker. Th... more The enzyme monoamine oxidase (MAO) has generated considerable interest as a biological marker. The serendipitous discovery that iproniazid was a weak MAO inhibitor (MAOI) led to the development and widespread use of MAOIs as antidepressants in the early 1950s. The-discovery of the two isoenzymes of MAO has led to the development of selective MAOIs that may have a more favorable side-effect profile. The regulation of MAO is multifactorial, and there is evidence that it involves estrogens. Improvement in mood and cognition reported in women on estrogen replacement therapy may also involve changes in MAO activity. The literature in this regard is reviewed here, and possible implications of the effects of estrogens on MAO activity are discussed.
Bookmarks Related papers MentionsView impact
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2021
Background Emotional wellbeing of healthcare workers is critical to the quality of patient care, ... more Background Emotional wellbeing of healthcare workers is critical to the quality of patient care, and effective function of health services. The corona virus disease-2019 (COVID-19) pandemic exerted unique physical and emotional demands on healthcare workers, however little is known about the emotional wellbeing of healthcare workers during the COVID-19 pandemic in resource-restricted settings. This study investigated the prevalence of psychological distress, and sleep problems in healthcare workers in a COVID-19 referral hospital in Nigeria. Methods A total of 303 healthcare workers were interviewed with the 12-item General Health Questionnaire (GHQ-12) to evaluate psychological distress, and the Pittsburgh Sleep Quality Index (PSQI) to assess multidimensional aspects of sleep, including quality, latency, duration, habitual efficiency, disturbances, use of sleeping medications and daytime dysfunction. Results The participants were mostly males, 183(60.4%) and mean age was 38.8(SD = 8.9) years. Most of the participants were married (70.3%), had spent less than 10 years in service (72.9%), and had no medical comorbidity (92.1%). The prevalence of psychological distress was 23.4%, and six in every ten participants reported sleep problems. The largest proportion of participants reported difficulty in sleep latency (81.5%), duration (71.3%), and daytime dysfunction (69.6%), while approximately one third (32%) each reported using sleep medication, and had difficulty with sleep quality. Psychological distress was inter-related with poor sleep problems (p = 0.001; effect size = 0.2). Conclusion The prevalence rates of psychological distress and sleep problems during the COVID-19 pandemic were several folds the rates previously reported in similar contexts. Preventative psychosocial support services for healthcare workers are indicated. The creation of a culturally-sensitive interdisciplinary blueprint for locally-viable actions model are strongly suggested ahead of future emergency situations.
Bookmarks Related papers MentionsView impact
BJPsych Advances, 2020
SUMMARY As experts in disaster mental health push to reframe disaster response as a preventive me... more SUMMARY As experts in disaster mental health push to reframe disaster response as a preventive medicine rather than its actual state of acute management, various factors should be considered. Although a whole population may be victim to the effects of disasters, particularly vulnerable are those with severe mental illness. Therefore, efforts geared to bolster trauma response should centre on these individuals, starting at a community level and reaching organisational and governmental endeavours and funding.
Bookmarks Related papers MentionsView impact
Acta Scientific Neurology, 2019
Bookmarks Related papers MentionsView impact
Journal of the American Academy of Child & Adolescent Psychiatry, 2019
Bookmarks Related papers MentionsView impact
Harefuah, 1978
Bookmarks Related papers MentionsView impact
The Journal of Clinical Psychiatry, 1997
Dysthymia is a chronic depressive condition that is quite prevalent. This condition can exact a s... more Dysthymia is a chronic depressive condition that is quite prevalent. This condition can exact a significant toll on the general health and quality of life in the affected individual. Despite the frequency and consequences of dysthymia, however, the condition is often not diagnosed or treated. We present data on prior treatment from 410 patients with DSM-III-R dysthymia, primary type, early onset without concurrent major depression. Axis I and II diagnoses were made by using the Structured Clinical Interviews for DSM-III-R, Patient Version (SCID-P) and SCID II for Personality Disorders. The Hamilton Rating Scale for Depression and the Clinical Global Impressions scale were also completed. Prior treatment was assessed, with special attention paid to previous antidepressant drug therapy and psychotherapy. Although the mean duration of dysthymia was about 30 years and almost half of the patients had previous episodes of major depression, only 41.3% had been treated with antidepressants and 56.1% with psychotherapy. A past history of major depression increased the frequency of prior antidepressant pharmacotherapy (45.7%) and psychotherapy (59.4%) compared with no history of major depression (36.8% and 40.9%, respectively). Comorbid personality disorder increased the likelihood of prior psychotherapy (70.7% vs. 49.6%) while having no effect on past pharmacotherapy. A history of substance abuse did not affect the history of antidepressant or psychotherapy treatment. In this study, dysthymia and psychosocial outcomes improved with sertraline and imipramine treatment. Dysthymic patients in this sample were significantly undertreated. Newer antidepressant agents may alter the potential for pharmacotherapy interventions in this vulnerable population.
Bookmarks Related papers MentionsView impact
The International Journal of Psychiatry in Medicine, 1993
Objective: Dysphoric Premenstrual Syndromes (PMS) are quite prevalent and in some women they are ... more Objective: Dysphoric Premenstrual Syndromes (PMS) are quite prevalent and in some women they are severe enough to warrant treatment. Their pathophysiology is still unknown, despite increased interest and research. Here we review the possible role of serotonin in the multidimensional interactive pathophysiology of PMS. Method: Over 170 articles are reviewed. An extensive library search has been conducted and articles are included because of their relevance to: 1) the phenomenology of PMS; 2) the putative association of serotonergic (5-HT) activity with syndromes that occur premenstrually; 3) changes in 5-HT activity along the menstrual cycle, especially the late luteal phase; 4) influence of gonadal hormones on serotonergic functions; 5) endocrine strategies for assessment of 5-HT abnormalities; and 6) treatment studies of PMS with serotonergic agonists. Results and Conclusions: The data presented here suggest that post-synaptic serotonergic responsivity might be altered during the l...
Bookmarks Related papers MentionsView impact
European Neuropsychopharmacology, 1996
Bookmarks Related papers MentionsView impact
Uploads
Papers by Uriel Halbreich