Papers by Syed Hadi Abbas Rizvi
Current pain and headache reports, 2015
Nearly 50 years ago, the seminal experiments of Melzack and Wall, culminating in the gate control... more Nearly 50 years ago, the seminal experiments of Melzack and Wall, culminating in the gate control theory, coupled with the discovery of endogenous opioid receptors, helped shape modern understandings of pain and provided interventionalists a potent therapeutic gateway to neuraxial analgesia. This paper emphasizes the historical antecedents, present state, and emerging future of the neuromodulatory technique of targeted intrathecal drug delivery (TIDD) for chronic pain. The strengths of TIDD are its customizability, reversibility, programmability, and low risk profile. Its benefits are evidenced by improved pain relief and quality of life and reduced demand for health-care resources.
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Pain management, 2012
SUMMARY Pain is a complex behavior process, the anatomy and physiology of which is not completely... more SUMMARY Pain is a complex behavior process, the anatomy and physiology of which is not completely understood, and is subject to continuous exploration and research. Following on the heels of Melzack and Wall's gate control theory of pain (1965), Shealey et al., in 1967, were the first to implant stimulation electrodes over the dorsal columns in an attempt to provide relief for patients with chronic, intractable pain. Since then, significant strides in both the technological and therapeutic sides have facilitated the evolution of spinal cord stimulation (SCS) in the management of a variety of pain pathologies. High-quality evidence attests to the efficacy and cost-effectiveness of this modality. In contrast to conventional medical management, SCS offers long-lasting symptom relief, improved quality of life and functional capability, often achieving these goals at a reduced cost. This article illustrates the present status, challenges and future of SCS.
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Neuromodulation : journal of the International Neuromodulation Society, 2014
The Neuromodulation Appropriateness Consensus Committee (NACC) of the International Neuromodulati... more The Neuromodulation Appropriateness Consensus Committee (NACC) of the International Neuromodulation Society (INS) evaluated evidence regarding the safety and efficacy of neurostimulation to treat chronic pain, chronic critical limb ischemia, and refractory angina and recommended appropriate clinical applications. The NACC used literature reviews, expert opinion, clinical experience, and individual research. Authors consulted the Practice Parameters for the Use of Spinal Cord Stimulation in the Treatment of Neuropathic Pain (2006), systematic reviews (1984 to 2013), and prospective and randomized controlled trials (2005 to 2013) identified through PubMed, EMBASE, and Google Scholar. Neurostimulation is relatively safe because of its minimally invasive and reversible characteristics. Comparison with medical management is difficult, as patients considered for neurostimulation have failed conservative management. Unlike alternative therapies, neurostimulation is not associated with medi...
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Pain management, 2014
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Neuromodulation: Technology at the Neural Interface, 2014
The International Neuromodulation Society (INS) has determined that there is a need for guidance ... more The International Neuromodulation Society (INS) has determined that there is a need for guidance regarding safety and risk reduction for implantable neurostimulation devices. The INS convened an international committee of experts in the field to explore the evidence and clinical experience regarding safety, risks, and steps to risk reduction to improve outcomes. The Neuromodulation Appropriateness Consensus Committee (NACC) reviewed the world literature in English by searching MEDLINE, PubMed, and Google Scholar to evaluate the evidence for ways to reduce risks of neurostimulation therapies. This evidence, obtained from the relevant literature, and clinical experience obtained from the convened consensus panel were used to make final recommendations on improving safety and reducing risks. The NACC determined that the ability to reduce risk associated with the use of neurostimulation devices is a valuable goal and possible with best practice. The NACC has recommended several practice modifications that will lead to improved care. The NACC also sets out the minimum training standards necessary to become an implanting physician. The NACC has identified the possibility of improving patient care and safety through practice modification. We recommend that all implanting physicians review this guidance and consider adapting their practice accordingly.
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Pain Practice, 2013
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Neuromodulation: Technology at the Neural Interface, 2014
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Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches, 2012
The field of neurostimulation has matured over the past decade to emerge as an important modality... more The field of neurostimulation has matured over the past decade to emerge as an important modality for the treatment of intractable chronic pain. Despite relatively high initial costs, a breadth of evidence exists, and extensive clinical experience suggests that spinal cord stimulation and intrathecal drug delivery systems are safe, effective, and economical. The benefits of neuromodulation are manifested in improved functional capability, health-related quality of life (HRQoL), and reduced demand for health-care resources. This results in long-term economic benefit and cost saving. Neuromodulation is a viable option for the early treatment of patients with intractable pain syndromes.
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Pain Medicine, 2013
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Neurosurgery, 2011
BACKGROUND: Complex regional pain syndrome (CRPS) I is a debilitating neuropathic pain disorder c... more BACKGROUND: Complex regional pain syndrome (CRPS) I is a debilitating neuropathic pain disorder characterized by burning pain and allodynia. Spinal cord stimulation (SCS) is effective in the treatment of CRPS I in the medium term but its long-term efficacy and ability to improve functional status remains controversial. OBJECTIVE: To evaluate the ability of SCS to improve pain, functional status, and quality of life in the long term. METHODS: We retrospectively analyzed 25 patients over a mean follow-up period of 88 months. The parameters for evaluation were visual analog scale (VAS), Oswestry Disability Index (ODI), Beck Depression Inventory (BDI), EuroQoL-5D (EQ-5D) and Short Form 36 (SF-36), and drug consumption. Evaluations were conducted at point of entry, 3 months, 12 months, and last follow-up at 88 months (mean). RESULTS: At baseline, the mean scores were VAS 8.4, ODI 70%, BDI 28, EQ-5D 0.30, and SF-36 24. In general, maximum improvement was recorded at follow-up at 3 months ...
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Current Pain and Headache Reports, 2013
Neuromodulation is based on the revolutionary concept that paresthesia-inducing electrical stimul... more Neuromodulation is based on the revolutionary concept that paresthesia-inducing electrical stimulation could be analgesic. Its historical basis emanates from Melzack and Wall's gate control theory of pain proposed in 1965. Neuromodulation has given us ready access to the systems of pain modulation and helped mature the understanding of the pathophysiology of pain. Physiologic studies highlight the complex ascending influence of neurostimulation on sensory processing. However, the present understanding of pain is rudimentary and evidence that neuromodulation works is modest. This paper emphasizes the historical antecedents, present state, and emerging future of 3 commonly applied neuromodulatory techniques--spinal cord stimulation, peripheral nerve and field stimulation, and deep brain stimulation--for chronic pain. It is hoped this article will enhance the understanding of neuromodulation and its role in pain management.
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The Clinical Journal of Pain, 2013
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16th Annual BACUS Symposium on Photomask Technology and Management, 1996
Although the traditional method of O/L measurement (relative comparison between two levels) has p... more Although the traditional method of O/L measurement (relative comparison between two levels) has proved to be a practical and cost effective way of measuring overlays, in the future this method will have to be supplemented by other means that require measurement of feature position in an absolute coordinate system and then comparing the output with the database rather than with some other level the accuracy of which remains to be established. The use of well calibrated Coordinate Measuring Instruments (CMI's) is one way to achieve the desired accuracy. But calibrating CMI's is a chicken-or-egg dilemma; you can't calibrate one without an accurately measured artifact, and you can't make the artifact without a well-calibrated instrument. Or so it seems. Positional self-calibration methods were invented to solve this problem and show great promise. But still there are many subtleties that must be resolved before such methods can be trusted. This paper explains the geometric basis for lattice methods of self-calibration and concludes with a theorem that demonstrates one of the striking difficulties that must be faced when relying on self- calibration algorithms.
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Papers by Syed Hadi Abbas Rizvi