Papers by Salvatore Patané
Journal of Materials Research, May 1, 1997
X-ray Photoelectron Spectroscopy (XPS) and optical studies have been performed on P(EO)n –NaI–TCN... more X-ray Photoelectron Spectroscopy (XPS) and optical studies have been performed on P(EO)n –NaI–TCNQ (n = 1, 10) systems, obtained by means of a solid state reaction technique. The electron spectroscopy, the absorption in the ultraviolet visible near infrared range, and the infrared transmission findings allow us to conclude that the interaction among the polymer, the iodide, and the electron acceptor molecule results in the formation of the ion-radical salt Na–TCNQ and in the oxidation of I− to the metallic state. The presence within the examined specimens of crystalline and amorphous phases has been confirmed by the results of Differential Scanning Calorimetry (DSC) measurements. The optical, electronic, and thermal properties of the P(EO)n–NaI–TCNQ mixtures have then been correlated to the results of preliminary ac electrical transport investigations.
Bookmarks Related papers MentionsView impact
Sensors and Actuators B-chemical, Mar 1, 2001
Bookmarks Related papers MentionsView impact
Bookmarks Related papers MentionsView impact
Bookmarks Related papers MentionsView impact
Applied Sciences, 2021
Synthetic dyes, dispersed in water, have harmful effects on human health and the environment. In ... more Synthetic dyes, dispersed in water, have harmful effects on human health and the environment. In this work, Ti and/or Zn oxide nanofibers (NFs) with engineered architecture and surface were produced via electrospinning followed by calcination. Calcination and subsequent cooling were operated at fast rates to generate porous NFs with capture centers to reduce the recombination rate of the photogenerated charges. After morphological and microstructural characterisation, the NFs were comparatively evaluated as photocatalysts for the removal of methylene blue from water under UV irradiation. The higher band gap and lower crystallinity were responsible for the lower photocatalytic activity of the ternary oxides (ZnTiO3 and Zn2TiO4) towards the degradation of the dye. The optimal loads of the highly performing binary oxides were determined. By using 0.66 mg mL−1 wurtzite ZnO for the discoloration of an aqueous solution with a dye concentration of 15 µM, a higher rate constant (7.94 × 10−2...
Bookmarks Related papers MentionsView impact
International Journal of Pharmaceutics, 2020
Nowadays, novel less-expensive nanoformulations for in situ-controlled and safe delivery of photo... more Nowadays, novel less-expensive nanoformulations for in situ-controlled and safe delivery of photosensitisers (PSs) against opportunistic pathogens in body-infections areas need to be developed. Antimicrobial photodynamic therapy (aPDT) is a promising approach to treat bacterial infections that are recalcitrant to antibiotics. In this paper, we propose the design and characterization of a novel nanophototherapeutic based on the trade cyclodextrin CAPTISOL® (sulfobutylether-beta-cyclodextrin, SBE-βCD) and 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphine tetrakis(p-toluenesulfonate) (TMPyP) to fabricate efficient biocompatible systems for aPDT. Spherical nanoassemblies of about 360 nm based on CAPTISOL®/TMPyP supramolecular complexes with 1:1 stoichiometry and equilibrium binding constant (Kb ≅ 1.32 × 105 M-1) were prepared with entrapment efficiency of ≅ 100% by simple mixing in aqueous media and freeze-drying. These systems have been characterized by complementary spectroscopy and microscopy techniques. Time resolved fluorescence pointed out the strong interaction of porphyrin monomer within nanoassemblies (τ2 ≅ 11 ns with an amount of ca 90%) and scarce self-aggregation of porphyrins have been observed. Singlet oxygen comparative determination (ϕΔ CAPTISOL®/TMPyP = 0.58) assessed their photodynamic potential. Release and photostability studies have been carried out under physiological conditions pointing out the role of CAPTISOL® to sustain porphyrin release for more than 2 weeks and to protect PS from photodegradation. Finally, photoantimicrobial activity of nanoassemblies vs free porphyrin have been investigated against Gram-negative P. aeruginosa, E. coli and Gram-positive S. aureus. The proposed nanosystems were able to photokill both Gram-positive and -negative bacterial cells similarly to TMPyP at MBC90 = 6 µM of TMPyP and at 42 J/cm2 light dose. However, with respect to the less selective free TMPyP in biological sites, nanoassemblies exhibit sustained release properties and a higher photostability thus optimizing the PDT effect at the site of action. These results can open routes for in vivo translational studies on nano(photo)drugs and nanotheranostics based on less expensive formulations of CD and PS.
Bookmarks Related papers MentionsView impact
Nanomaterials, 2020
Clusters of superparamagnetic iron oxide nanoparticles (SPIONs) have been incorporated into the h... more Clusters of superparamagnetic iron oxide nanoparticles (SPIONs) have been incorporated into the hydrophobic core of polyethylene glycol (PEG)-modified phospholipid micelles. Two different PEG-phospholipids have been selected to guarantee water solubility and provide an external corona, bearing neutral (SPIONs@PEG-micelles) or positively charged amino groups (SPIONs@NH2-PEG-micelles). Under acidic conditions and with specific mixing protocols (porphyrin first, PF, or porphyrin last, PL), the water-soluble 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin (TPPS) forms chiral J-aggregates, and in the presence of the two different types of magnetic micelles, an increase of the aggregation rates has been generally observed. In the case of the neutral SPIONs@PEG-micelles, PL protocol affords a stable nanosystem, whereas PF protocol is effective with the charged SPIONs@NH2-PEG-micelles. In both cases, chiral J-aggregates embedded into the magnetic micelles (TPPS@SPIONs@micelles) have been ...
Bookmarks Related papers MentionsView impact
Langmuir : the ACS journal of surfaces and colloids, Jan 25, 2018
Amphiphilic cyclodextrins (aCD) are an intriguing class of carrier systems which, recently, have ... more Amphiphilic cyclodextrins (aCD) are an intriguing class of carrier systems which, recently, have been proposed to deliver porphyrinoids and anticancer drugs or combined dose of both for dual therapeutic applications. The design of nanoassemblies based on aCD and photosensitisers (PSs) aims to preserve the PDT efficacy of PS, reducing the tendency of PS to self-aggregate, without affecting the quantum yield of singlet oxygen (1O2) production, and, not less importantly, minimizing dark toxicity and reducing photosensitization effects. With this idea in mind, in this paper, we focus on nanoassemblies between a non-ionic aCD (SC6OH) and an unprecedented synthesized halo-alkyl tailored iodinated BODIPY dye, a class of molecules which recently have been successfully proposed as a stimulating alternative to porphyrinoids for their high photodynamic efficacy. Nanoassemblies of BODIPY/aCD (BL01I@SC6OH) were prepared in different aqueous media by evaporation of mixed organic film of aCD and B...
Bookmarks Related papers MentionsView impact
Chirality, Jan 8, 2015
A new porphyrin bearing four R or S hydrogenated citronellal units directly bound to the meso pos... more A new porphyrin bearing four R or S hydrogenated citronellal units directly bound to the meso positions of the porphyrin ring was synthesized and fully characterized through MALDI-TOF, NMR, UV/Vis absorption, and fluorescence emission spectroscopies. Both enantiomers exhibit a monomeric nature in a series of organic solvents. Acting on the polarity of the solvent, i.e., increasing the amount of water in mixture with acetone, aggregation occurs, as revealed by UV/Vis absorption, fluorescence emission, and resonance light scattering. The occurrence of both H- and J-type aggregates was suggested by fluorescence lifetime measurements. In contrast to the monomeric species, these aggregates exhibit CD spectra reflecting the chirality of the building blocks. AFM microscopy shows that micrometer ribbon-like structures form by the casting solution of these porphyrins in acetone/water onto a glass surface. Chirality 00:000-000, 2015. © 2015 Wiley Periodicals, Inc.
Bookmarks Related papers MentionsView impact
International Quantum Electronics Conference, 2005.
We propose a method to follow in real time the growth of topographical features by a near-field s... more We propose a method to follow in real time the growth of topographical features by a near-field simultaneously write-read process. Data are analyzed using formula derived from the classical laminar flow equations. Azobenzene-containing polymers have been largely studied as promising materials for optical data storage. They may be synthesized with azobenzene moieties both in the main polymer chains or in the side chains. Complete trans-cis-trans isometization cycles of the azo-groups may be driven by suitable laser light. Consecutive isomerization cycles of the azo-groups lead to a statistical net orientation of the azobenzene molecules that result into a photo-induced birefringence [1]. In addition, azobenzene moieties isomerization leads also to a mass migration on the free surface of azo containing polymer films. This phenomenon has been found to be strongly related to the laser polarization state and atomic force investigations have showed that optical birefringence remains even after the disappearance of the topographical features [2]. The reasons for the surface modification that may follow azo-groups isomerization are still matter of discussion. Among the different models that have been proposed, the description based on classical laminar flow (Navier-Stokes equations) seems promising and has already been used by some groups to describe their experimental observations [3,4]. We have exploited this model into near-field microscopy (SNOM) experiments, by monitoring in situ the photo-induced growth of dots on the free surface of azo copolymer films. We have then compared our data with predictions based on Navier-Stokes equations and we have found an excellent agreement. In particular, we have used azo-based cpolymers made of polymethacrylate (PMA) and polymethacrylate modified by the insertion in the fourth position (PMA4) of an azobenzene mesogenic unit (3-methyl-4’-pentyloxy) connected to the chain by a hexamethylene spacer. Features a few tens of nanometers wide, either topographical or pure holographic (birefrengence), have already been produced on those samples [5, 6]. We investigated both 30/70 and 50/50 PMA/PMA4 thin films (~120nm thick) produced by spin-coating on glass slices. The mass migration (dot’s growth) has been obtained by illuminating the sample surface with a 417 nm laser diode through a tapered SNOM probe. The power launched into the SNOM optical fiber was 0.1 mW while the sample temperature was fixed by thermal contact with a temperature control system on the microscope sample holder. The typical shape of the dots we have written with near field illumination, is shown in figure 1. Here, we report the topographical image of a dot on 50/50 PMA/PMA4 sample taken by the SNOM itself. On the right side of the image, central sections of the dot are shown. The full width at half maximum of the dot sections are respectively 120 nm and 200 nm. The elliptical shape may be related to the shape of the SNOM probe aperture or to the polarization-dependent nature of the mass migration phenomenon. The glass transition temperature (bulk values) Tg for 50/50 copolymer is around 50 °C while Tg for 30/70 is about 45 °C [7]. Both samples have been annealed at 80 °C just before the experiment. In our experiment, we have first approached the JWH4-6
Bookmarks Related papers MentionsView impact
Sensors and Actuators B: Chemical, 2001
Bookmarks Related papers MentionsView impact
Nano Science and Technolgy
... up a monocrystal GaAs tip that took advantage of the ability of the GaAs single crystal eithe... more ... up a monocrystal GaAs tip that took advantage of the ability of the GaAs single crystal either to ... owing to the high curvature of the metal surface at the rim (tip effect, lightning-rod effect). ... 3.11 the results of a FDTD simulation performed on a probe having a cone angle of 20 ◦ , with ...
Bookmarks Related papers MentionsView impact
Conference Digest. 2000 Conference on Lasers and Electro-Optics Europe (Cat. No.00TH8505)
ABSTRACT Several species of bacteria undergo continuous modifications of cellular fitness under n... more ABSTRACT Several species of bacteria undergo continuous modifications of cellular fitness under nutrition or physical stress conditions. The variation of the cell dimensions is one of the characteristics which strongly depends on nutrition. Cell shape and dimension during extended periods of starvation are usually followed in-vivo by optical microscopy. However, classical microscopy has not been able to discriminate cells which remain active or restores their activity alter dimension shrinking from those cells which are damaged to an extent that they could not recover on the route leading to cell death. By using near field optical microscopy (SNOM), we have investigated in-vivo the morphological, structural and ultra structural evolution of a Pseudomonas Auriginosa ATCC 27853 microbial population over a period of 45 days nutritional stress
Bookmarks Related papers MentionsView impact
NanoScience and Technology, 2009
Bookmarks Related papers MentionsView impact
Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications, 2008
Bookmarks Related papers MentionsView impact
Nanoscale, Jan 21, 2014
Polarization modulated scanning near-field optical microscopy (PM-SNOM) is effective in detecting... more Polarization modulated scanning near-field optical microscopy (PM-SNOM) is effective in detecting circular and linear dichroism with sub-wavelength resolution. PM-SNOM investigation of the chiroptical properties of single ribbon-like nanosized J-aggregates formed by acid induced aggregation of tris-(4-sulfonatophenyl)phenylporphyrin is reported. Linear dichroism maps give evidence of well-organized chromophores packed in linear arrays within the structure of the nanoribbons. Circular dichroism maps indicate that the molecules forming the nanoribbon have an inherently chiral structure at the local scale.
Bookmarks Related papers MentionsView impact
The Journal of Physical Chemistry C, 2008
Bookmarks Related papers MentionsView impact
Physical Review B, 2010
Bookmarks Related papers MentionsView impact
Optics Express, 2014
Bookmarks Related papers MentionsView impact
Journal of the American Chemical Society, 2003
Simple irradiation by UV light of porphyrin TpyP and its zinc(II) and manganese(III) metal deriva... more Simple irradiation by UV light of porphyrin TpyP and its zinc(II) and manganese(III) metal derivatives in chlorinated solvents leads to the deposition on silica of mesoscale aggregates. The process is due to the photochemical decomposition of the solvent with generation of HCl, which causes the precipitation of a protonated form. The morphology of the resulting objects is driven by the nature of the inserted metal ion.
Bookmarks Related papers MentionsView impact
Uploads
Papers by Salvatore Patané