Iron deficiency is one of the most common micronutrient deficiency in infancy and childhood. The ... more Iron deficiency is one of the most common micronutrient deficiency in infancy and childhood. The main long lasting effect of iron deficiency anemia in infancy is poor neurocognitive development. Despite early treatment with iron supplements, lower cognitive performance remains even after reaching adulthood. Therefore iron deficiency anemia should be regarded not only as a haematological problem, but as a result of imperfections in the social system. Preventive strategies occupie most important place ensuring the normal development of the child. The main recommendations regarding iron deficiency prophylaxis are as follows: delayed umbilical cord clamping, exclusive breastfeeding until 6 months of age, iron fortified formula for non-breastfed infants, iron supplements for infants with risk factors, complementary feeding starting at 6 months of age, avoiding cow‘s milk until 12 months of age and restriction of intake to less than 500 ml per day for toddlers. The article analyzes iron d...
Kauno medicinos universiteto Vaikø ligø klinika, 2 Biomedicininiø tyrimø institutas, 3 Vilniaus u... more Kauno medicinos universiteto Vaikø ligø klinika, 2 Biomedicininiø tyrimø institutas, 3 Vilniaus universiteto vaikø ligoninë Raktaþodþiai: vaikai, onkologinës ligos, gyvenimo kokybë. Santrauka. Lietuvoje per metus onkologinëmis ligomis suserga apie 80 vaikø. Nuo 2005 metø Lietuvoje pradëtas vaikø, serganèiø onkologinëmis ligomis, gyvenimo kokybës tyrimas. Tiriamieji nuo 2005 m. kovo iki 2006 m. kovo mënesio Lietuvoje onkologine liga susirgae 218 metø vaikai bei jø tëvai. Tyrimui naudotos PedsQL (Pediatric Quality of Life Inventory TM) anketos, skirtos su sveikata susijusios 218 metø vaikø ir paaugliø gyvenimo kokybës tyrimams. PedsQL anketos parengtos pagal vaikø paþintinës veiklos raidà ir skirstomos á 24, 57, 812 ir 1318 metø grupes. Anketas savarankiðkai pildo 818 metø vaikai ir paaugliai bei visø amþiaus grupiø vaikø tëvai. 20052006 metais tyrime dalyvavo 63 ðeimos, kuriose vaikas susirgo onkologine liga. Anketas uþpildë 44 vaikai bei paaugliai, kuriø amþius nuo 5 iki 18 metø, ir 53 tëvai (motina, tëvas ar kitas artimas vaikui asmuo), kurie slaugë sergantá vaikà. Analizuojant gautus duomenis, paaiðkëjo, kad onkologinëmis ligomis sergantys visø amþiaus grupiø vaikai ir jø tëvai fizinae sveikatà vertino prasèiau nei psichosocialinae. Tëvø nuomone, visø amþiaus grupiø vaikai patyrë neigiamø emocijø: maþesniems vaikams didþiausià baimae kelia kraujo ëmimas tyrimams, o vyresnieji nerimauja dël ateities. Vyriausios amþiaus grupës (1318 metø) paaugliai daþniau nei jaunesni jautë nuovargá, susijusá su liga.
Vaikų onkohematologijos centras, Vilniaus universiteto Medicinos fakulteto Vaikų ligų klinika 2 V... more Vaikų onkohematologijos centras, Vilniaus universiteto Medicinos fakulteto Vaikų ligų klinika 2 Vaikų onkohematologijos centras, Vaikų ligoninė, VšĮ Vilniaus universiteto ligoninės Santariškių klinikų filialas
The objective of this study was to determine the influence of physical activity to the quality of... more The objective of this study was to determine the influence of physical activity to the quality of life in pediatric with haemophilia. Methods. 32 patients with severe haemophilia A and B were enrolled in the study, including 16 boys from Toronto Sick Kids hospital rehabilitation department and 16 – from Children‘s Hospital Physical Medicine and Rehabilitation Center. The age range was 4-17 years. Patient‘s joints state was assessed by Haemophilia Health Joint Score (HJHS), functional independence by Functional Independence Score in Haemophilia (FISH) and quality of life by using the Canadian Children with Haemophilia Quality of Life Questionnaire (CHO-KLAT). Statistical analysis was performed using „SPSS Statistics 20“. Results and conclusions. Our results showed that children with haemophilia receiving prophylactic treatment and regular physical therapy have significantly better joint state, functional independence and quality of life. Children psychoemotional state, quality of treatment and opportunities to participate in sporting activities have significant impact on their quality of life. The prophylactic treatment and physical therapy should be combine and well organized in order to improve children with haemophilia quality of life in Lithuania. Article in Lithuanian doi:10.5200/sm-hs.2012.043
Background. The aim of this study is to investigate the prevalence of anemia, the frequency of th... more Background. The aim of this study is to investigate the prevalence of anemia, the frequency of the most common anemia-related symptoms and to assess anemia risk factors among school-age children. Materials and methods. The study was performed from August 2002 to January 2003, with 318 children having taken part in the study. They were divided into three groups: Group I-6-8-y-old children, Group II-teenage girls, and Group IIIteenage boys. All parents of 6-8-year-old children, teenage girls and boys were asked to fill in the questionnaires about the presence of anemia-related symptoms, and the answers were examined by the pediatrician. Capillary blood including complete blood count with red blood cell indices was analysed using automated hematology analysers. Statistical data analysis was performed using SPSS 10.1 for Windows software statistical package. Results. The overall percentage of 10.1% of anemic children was found in Šiauliai region among 6-16-year-old children. Anemia was diagnosed to 10.8% of 6-8-year-old children, 17.8% of teenage girls and 3.4% of teenage boys. The prevalence of anemiarelated symptoms in all study group was 52.2%. Anemia-related symptoms predominated among teenage girls, giving an overall frequency of 78.8%. Conclusions. Complete anamnesis and appearance of anemia symptoms is not enough to detect anemia; consequently, there is a need of blood test to perform. The presence of anemia-related symptoms is also very frequent among children without anemia. Prelatent or latent iron deficiency might be the reason, but capillary blood test is not enough to prove this. Further and more detailed tests are needed. Analysing the prevalence of anemia and anemia-related symptoms among schoolchildren, the highest prevalence was defined among teenage girls. Teenage girls belong to the iron deficiency anemia risk group, so we would strongly reccommend prophylactic measures to be applied: at least one anemia screening test during adolescence and an oral iron preparation for prophylaxis.
Introduction. Wilms tumour (WT) is the most common childhood abdominal malignancy, with an averag... more Introduction. Wilms tumour (WT) is the most common childhood abdominal malignancy, with an average annual incidence of 1 in 10,000 children. The study published in 2002 reported lower survival rates of WT in Lithuania in comparison to the data of SIOP-9 study and the European Organization for Research and Treatment of Cancer (EORTC). We aimed to assess current diagnostic approach and treatment results of patients with WT treated at our institution and to compare the results with the previously published study. Materials and methods. A retrospective single-centre study was performed. 48 patients with WT registered at the institutional database from 2000 to 2018 were enrolled. An estimated 5-year overall survival (OS5y) and 2-year event-free survival (EFS2y) by stage and risk groups was calculated using IBM SPSS. A comparative analysis of two time periods – 2000–2008 and 2009–2018 – was carried out. Results. Forty-two (87.5%) patients presented with localised disease and 6 (12.5%) wit...
Nearly 80 new cases of pediatric cancer are diagnosed in Lithuania each year. Since 2005, we have... more Nearly 80 new cases of pediatric cancer are diagnosed in Lithuania each year. Since 2005, we have been conducting a study evaluating the quality of life of children suffering from cancer in Lithuania. The participants were children between the ages of 2 and 18 years, diagnosed with oncologic diseases during the period from March 2005 to March 2006, and their parents. The PedsQLTM (Pediatric Quality of Life InventoryTM) was used. This questionnaire is specifically designed for investigating the quality of life in children between the ages of 2 and 18 years. The PedsQL questionnaire is designed according to the level of cognitive activity of children and applied to children of four age groups: 2–4, 5–7, 8–12, and 13–18 years of age. The questionnaires were completed by children between the ages of 8 and 18 years in addition to parents of children from all age groups. The families of 63 children suffering from cancer participated in the study. A total of 44 children and teenagers betwe...
Iron deficiency is one of the most common micronutrient deficiency in infancy and childhood. The ... more Iron deficiency is one of the most common micronutrient deficiency in infancy and childhood. The main long lasting effect of iron deficiency anemia in infancy is poor neurocognitive development. Despite early treatment with iron supplements, lower cognitive performance remains even after reaching adulthood. Therefore iron deficiency anemia should be regarded not only as a haematological problem, but as a result of imperfections in the social system. Preventive strategies occupie most important place ensuring the normal development of the child. The main recommendations regarding iron deficiency prophylaxis are as follows: delayed umbilical cord clamping, exclusive breastfeeding until 6 months of age, iron fortified formula for non-breastfed infants, iron supplements for infants with risk factors, complementary feeding starting at 6 months of age, avoiding cow‘s milk until 12 months of age and restriction of intake to less than 500 ml per day for toddlers. The article analyzes iron d...
Kauno medicinos universiteto Vaikø ligø klinika, 2 Biomedicininiø tyrimø institutas, 3 Vilniaus u... more Kauno medicinos universiteto Vaikø ligø klinika, 2 Biomedicininiø tyrimø institutas, 3 Vilniaus universiteto vaikø ligoninë Raktaþodþiai: vaikai, onkologinës ligos, gyvenimo kokybë. Santrauka. Lietuvoje per metus onkologinëmis ligomis suserga apie 80 vaikø. Nuo 2005 metø Lietuvoje pradëtas vaikø, serganèiø onkologinëmis ligomis, gyvenimo kokybës tyrimas. Tiriamieji nuo 2005 m. kovo iki 2006 m. kovo mënesio Lietuvoje onkologine liga susirgae 218 metø vaikai bei jø tëvai. Tyrimui naudotos PedsQL (Pediatric Quality of Life Inventory TM) anketos, skirtos su sveikata susijusios 218 metø vaikø ir paaugliø gyvenimo kokybës tyrimams. PedsQL anketos parengtos pagal vaikø paþintinës veiklos raidà ir skirstomos á 24, 57, 812 ir 1318 metø grupes. Anketas savarankiðkai pildo 818 metø vaikai ir paaugliai bei visø amþiaus grupiø vaikø tëvai. 20052006 metais tyrime dalyvavo 63 ðeimos, kuriose vaikas susirgo onkologine liga. Anketas uþpildë 44 vaikai bei paaugliai, kuriø amþius nuo 5 iki 18 metø, ir 53 tëvai (motina, tëvas ar kitas artimas vaikui asmuo), kurie slaugë sergantá vaikà. Analizuojant gautus duomenis, paaiðkëjo, kad onkologinëmis ligomis sergantys visø amþiaus grupiø vaikai ir jø tëvai fizinae sveikatà vertino prasèiau nei psichosocialinae. Tëvø nuomone, visø amþiaus grupiø vaikai patyrë neigiamø emocijø: maþesniems vaikams didþiausià baimae kelia kraujo ëmimas tyrimams, o vyresnieji nerimauja dël ateities. Vyriausios amþiaus grupës (1318 metø) paaugliai daþniau nei jaunesni jautë nuovargá, susijusá su liga.
Vaikų onkohematologijos centras, Vilniaus universiteto Medicinos fakulteto Vaikų ligų klinika 2 V... more Vaikų onkohematologijos centras, Vilniaus universiteto Medicinos fakulteto Vaikų ligų klinika 2 Vaikų onkohematologijos centras, Vaikų ligoninė, VšĮ Vilniaus universiteto ligoninės Santariškių klinikų filialas
The objective of this study was to determine the influence of physical activity to the quality of... more The objective of this study was to determine the influence of physical activity to the quality of life in pediatric with haemophilia. Methods. 32 patients with severe haemophilia A and B were enrolled in the study, including 16 boys from Toronto Sick Kids hospital rehabilitation department and 16 – from Children‘s Hospital Physical Medicine and Rehabilitation Center. The age range was 4-17 years. Patient‘s joints state was assessed by Haemophilia Health Joint Score (HJHS), functional independence by Functional Independence Score in Haemophilia (FISH) and quality of life by using the Canadian Children with Haemophilia Quality of Life Questionnaire (CHO-KLAT). Statistical analysis was performed using „SPSS Statistics 20“. Results and conclusions. Our results showed that children with haemophilia receiving prophylactic treatment and regular physical therapy have significantly better joint state, functional independence and quality of life. Children psychoemotional state, quality of treatment and opportunities to participate in sporting activities have significant impact on their quality of life. The prophylactic treatment and physical therapy should be combine and well organized in order to improve children with haemophilia quality of life in Lithuania. Article in Lithuanian doi:10.5200/sm-hs.2012.043
Background. The aim of this study is to investigate the prevalence of anemia, the frequency of th... more Background. The aim of this study is to investigate the prevalence of anemia, the frequency of the most common anemia-related symptoms and to assess anemia risk factors among school-age children. Materials and methods. The study was performed from August 2002 to January 2003, with 318 children having taken part in the study. They were divided into three groups: Group I-6-8-y-old children, Group II-teenage girls, and Group IIIteenage boys. All parents of 6-8-year-old children, teenage girls and boys were asked to fill in the questionnaires about the presence of anemia-related symptoms, and the answers were examined by the pediatrician. Capillary blood including complete blood count with red blood cell indices was analysed using automated hematology analysers. Statistical data analysis was performed using SPSS 10.1 for Windows software statistical package. Results. The overall percentage of 10.1% of anemic children was found in Šiauliai region among 6-16-year-old children. Anemia was diagnosed to 10.8% of 6-8-year-old children, 17.8% of teenage girls and 3.4% of teenage boys. The prevalence of anemiarelated symptoms in all study group was 52.2%. Anemia-related symptoms predominated among teenage girls, giving an overall frequency of 78.8%. Conclusions. Complete anamnesis and appearance of anemia symptoms is not enough to detect anemia; consequently, there is a need of blood test to perform. The presence of anemia-related symptoms is also very frequent among children without anemia. Prelatent or latent iron deficiency might be the reason, but capillary blood test is not enough to prove this. Further and more detailed tests are needed. Analysing the prevalence of anemia and anemia-related symptoms among schoolchildren, the highest prevalence was defined among teenage girls. Teenage girls belong to the iron deficiency anemia risk group, so we would strongly reccommend prophylactic measures to be applied: at least one anemia screening test during adolescence and an oral iron preparation for prophylaxis.
Introduction. Wilms tumour (WT) is the most common childhood abdominal malignancy, with an averag... more Introduction. Wilms tumour (WT) is the most common childhood abdominal malignancy, with an average annual incidence of 1 in 10,000 children. The study published in 2002 reported lower survival rates of WT in Lithuania in comparison to the data of SIOP-9 study and the European Organization for Research and Treatment of Cancer (EORTC). We aimed to assess current diagnostic approach and treatment results of patients with WT treated at our institution and to compare the results with the previously published study. Materials and methods. A retrospective single-centre study was performed. 48 patients with WT registered at the institutional database from 2000 to 2018 were enrolled. An estimated 5-year overall survival (OS5y) and 2-year event-free survival (EFS2y) by stage and risk groups was calculated using IBM SPSS. A comparative analysis of two time periods – 2000–2008 and 2009–2018 – was carried out. Results. Forty-two (87.5%) patients presented with localised disease and 6 (12.5%) wit...
Nearly 80 new cases of pediatric cancer are diagnosed in Lithuania each year. Since 2005, we have... more Nearly 80 new cases of pediatric cancer are diagnosed in Lithuania each year. Since 2005, we have been conducting a study evaluating the quality of life of children suffering from cancer in Lithuania. The participants were children between the ages of 2 and 18 years, diagnosed with oncologic diseases during the period from March 2005 to March 2006, and their parents. The PedsQLTM (Pediatric Quality of Life InventoryTM) was used. This questionnaire is specifically designed for investigating the quality of life in children between the ages of 2 and 18 years. The PedsQL questionnaire is designed according to the level of cognitive activity of children and applied to children of four age groups: 2–4, 5–7, 8–12, and 13–18 years of age. The questionnaires were completed by children between the ages of 8 and 18 years in addition to parents of children from all age groups. The families of 63 children suffering from cancer participated in the study. A total of 44 children and teenagers betwe...
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