Papers by Leticia Lino Pérez
Tratado de hepatología. Tomo II, 1996, ISBN 8447202674, págs. 967-970, 1996
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Revista Médica del Hospital General de México, 2017
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Qualitative Health Research, 2016
The aim of this article was to describe and analyze the doctor–patient relationship between fibro... more The aim of this article was to describe and analyze the doctor–patient relationship between fibromyalgia patients and rheumatologists in public and private health care contexts within the Mexican health care system. This medical anthropological study drew on hospital ethnography and patients’ illness narratives, as well as the experiences of rheumatologists from both types of health care services. The findings show how each type of medical care subsystem shape different relationships between patients and doctors. Patient stigmatization, overt rejection, and denial of the disease’s existence were identified. In this doctor–patient-with-fibromyalgia relationship, there are difficult encounters, rather than difficult patients. These encounters are more fluid in private consultations compared with public hospitals. The doctor-centered health care model is prevalent in public institutions. In the private sector, we find the characteristics of the patient-centered model coexisting with th...
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JCR: Journal of Clinical Rheumatology, 2015
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Annals of the Rheumatic Diseases, 2013
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JCR: Journal of Clinical Rheumatology, 2008
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Clinical Rheumatology, 2009
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Clinical Rheumatology, 2011
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Arthritis Care & Research, 2012
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Arthritis & Rheumatism, 1999
To compare the efficacy of 2 low-dose oral methotrexate (MTX) schedules in maintaining remission ... more To compare the efficacy of 2 low-dose oral methotrexate (MTX) schedules in maintaining remission in patients with rheumatoid arthritis (RA). Patients with RA were included if they were receiving treatment with weekly MTX for at least 9 months and the RA was in remission (defined by American College of Rheumatology [ACR] criteria) for at least 6 months. Patients were stratified by treatment and randomly assigned to weekly or every-other-weekly (EOW; reducing their monthly dose by half) treatment with MTX. Patients were evaluated by a rheumatologist (blinded to the treatment schedule) at baseline and at 6, 12, and 24 weeks. The evaluations included joint counts, Ritchie Articular Index, Health Assessment Questionnaire Disability Index, physician's and patient's global health assessments, visual analog scale for pain, and incidence of adverse effects. Laboratory evaluations were done at baseline and at week 24. Fifty-one patients were included (26 taking weekly MTX, 25 taking EOW MTX). Baseline comparisons showed no differences between the groups. The mean duration of RA was <3 years in both groups, and they had been started on weekly MTX treatment early after diagnosis. After 24 weeks, >90% of the patients in both groups continued in remission. Evaluations of disease activity at 6 and 12 weeks showed no between-group differences. EOW MTX patients who experienced relapse were switched back to weekly MTX, and after a few weeks, their RA was again controlled. The incidence of adverse effects was slightly higher in the weekly MTX group, although the difference did not reach statistical significance. The observed laboratory values were very similar for both groups, except for the serum aspartate aminotransferase and alanine aminotransferase levels, which decreased in the EOW MTX group and were statistically significant at week 24 (P = 0.04 and P = 0.006, respectively). EOW MTX represents a valid therapeutic alternative for a specific subgroup of RA patients, as outlined by the ACR remission criteria. Patients with a short disease duration who were treated early after disease onset with weekly MTX and who achieve sustained remission have a higher probability of success with the EOW MTX schedule.
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JCR: Journal of Clinical Rheumatology, 2009
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Objective: To describe systemic and ocular manifestations in patients with relapsing polychondrit... more Objective: To describe systemic and ocular manifestations in patients with relapsing polychondritis, as well as its clinical course. We found its prevalence at the General Hospital of Mexico. Material and Methods: Four patients were evaluated in Ophthalmology Department at the General Hospital of Mexico, with the diagnosis of relapsing polychondritis. All of them underwent a through rheumathologic and ophthalmologic assesment. Results: The presentation age was of 64, 43 and 34 years old in 2 cases; one man and three women. The main ocular manifestations were: episcleritis, anterior diffuse scleritis, keratitis and anterior uveitis. Visual acuity was impaired in all the patients. The main systemic manifestations were: chondritis at the auricle and nasal cartilages , arthritis, laringeal and/or tracheal chondritis, and cochlear and vestibular damage. Conclusions: Relapsing polychondritis is a rare condition that might be related to very important ocular and extraocular sequelae, and e...
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Reumatología …, 2006
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Papers by Leticia Lino Pérez