Papers by P. Dinesh Kumar
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Far East Journal of Electronics and Communications, 2021
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Digital Image Processing, 2017
The detection of blood vessels from the retinal images is generally a slow process. Also, it is u... more The detection of blood vessels from the retinal images is generally a slow process. Also, it is used to detect the diabetes in early stages by evaluating all the retinal blood vessels together. As digital imaging and computing power increasingly develop, so these technologies are used in ophthalmology. The main divisions include Image processing, Image analysis and Computer vision are increasingly becoming more prominence in all fields of medical science, and they are especially suited to the field of modern ophthalmology. Exciting developments in image processing relevant to ophthalmology over the past 15 years includes the progress being made towards developing a good solution for diseases such as diabetic retinopathy, age-related macular degeneration and retinopathy of prematurity. The quantitative measurements of retinal vascular topography using digital image analysis from retinal photography have been used as research tools to better understand the relationship between the ret...
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International Journal of Scientific Research in Computer Science, Engineering and Information Technology, 2021
Facial expression, as one of the most significant means for human beings to show their emotions a... more Facial expression, as one of the most significant means for human beings to show their emotions and intensions in the process of communication, plays a significant role in human interfaces. In recent years, facial expression recognition has been under especially intensive investigation, due conceivably to its vital applications in various fields including virtual reality, intelligent tutoring system, health-care and data driven animation. The main target of facial expression recognition is to identify the human emotional state (e.g., anger, contempt, disgust, fear, happiness, sadness, and surprise ) based on the given facial images. This paper deals with the Facial expression detection and recognition through Viola-jones algorithm and HCNN using LSTM method. It improves the hypothesis execution enough and meanwhile inconceivably reduces the computational costs. In feature matching, the author proposes Hybrid Scale-Invariant Feature Transform (SIFT) with double δ-LBP (Dδ-LBP) and it ...
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Computer vision is one among the thrust research area in the field of Image processing. Facial ex... more Computer vision is one among the thrust research area in the field of Image processing. Facial expression recognition is one among the thrust research dimension in computer vision. The process of recognition and identification is important due to the similarity of facial expressions. The motivation behind this research area is its capability to resolve an image processing problem and its wide range of applications. The main rationale of all images processing and computer vision algorithms is to build the visual data in a useful manner. For this reason in the domain of computer vision, the facial expression recognition begins with its applications in the HCI (Human Computer Interaction) where visual look of human, sight and touch sensations (also known as moods) and voice are utilized at the same time. This research article reviews several literatures pertaining to facial expression recognition.
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Journal of Chemical Sciences, Nov 1, 2009
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ABSTRACT The area of polymer–drug conjugates is expanding spectacularly in recent years. From mac... more ABSTRACT The area of polymer–drug conjugates is expanding spectacularly in recent years. From macromolecular prodrugs of established anticancer agents to novel targeted polymeric drug conjugate systems, their application has expanded exponentially. Delivery of new anticancer agents, combination therapies, treatment of diseases other than cancer, and novel polymer architectures are highly exciting and promising areas. It is hoped that in the next decade, some of these new approaches will reach clinical evaluation and few will see the light of marketing phase. The successful development of first-generation polymer–drug conjugates in the mid-1980s and 1990s has inspired more recent studies assessing their potential as drug delivery platforms for combination therapy. These early works unveiled unexpected therapeutic benefits but raised new issues, in particular in relation to “system design.” A better understanding of how drug combinations impact on cellular and molecular mechanisms is needed to rationally design new therapeutics. In nutshell it is to be believed that the interdisciplinary scientific approach to the applications of polymer–drug conjugate (PDC) will result in their translation into the clinic within this decade.
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ABSTRACT In the present study, antihyperglycemic and hypolipidemic effects of stem extract of Eup... more ABSTRACT In the present study, antihyperglycemic and hypolipidemic effects of stem extract of Euphorbia hirta were studied in albino mice by administering graded oral doses (250 and 500 mg/kg body weight) of the extract for 21 days. The ethanolic and petroleum ether ...
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Microelectronic Engineering, Mar 31, 2010
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Acta Pharmaceut, 2008
Citrullus colocynthis (L.) Schrad.(Cucurbitaceae) je ljekovita biljka koja se tradicionalno upotr... more Citrullus colocynthis (L.) Schrad.(Cucurbitaceae) je ljekovita biljka koja se tradicionalno upotrebljava kao abortiv i za liječenje konstipacije, edema, bakterijskih infekcija, karcinoma i dijabetesa. Preliminarno fitokemijsko pretraivanje ukazalo je na prisutnost velikih ...
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Vacuum, 2004
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Nanotechnology has achieved the status as one of the vital research endeavors of 21st century, wh... more Nanotechnology has achieved the status as one of the vital research endeavors of 21st century, which may be called as “Nano-Century” with nanotechnology making its presence felt in different spheres of lives. Nanotechnology may be defined as the creation of materials, drugs and devices that are used to manipulate matter of size in the range of 1-100nm. Nanotechnology has found its applications in many fields related to medicine including novel drug delivery systems. Many different types of nanosystems have been utilized in diagnostics and therapeutics of various diseases. To subside the disadvantages of conventional cancer therapeutics, nanotechnology has been given considerable attention. The purpose of this expert review is to discuss the impact of nanotechnology in the treatment of the cancer. These have been applied to improve drug delivery and to overcome some of the problems of drug delivery in cancer. Current nanotechnology platforms for cancer therapeutics encompass a vast a...
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Conventional drug delivery systems are known to provide an immediate release of drug, in which on... more Conventional drug delivery systems are known to provide an immediate release of drug, in which one can not control the release of the drug and can not maintain effective concentration at the target site forlonger time. Osmotically controlled drug delivery systems (OCDDS) are most promising systems for controlleddrug delivery. Osmotically controlled drug delivery systems utilize osmotic pressure for controlled delivery ofactive agents. Various patents are available for osmotic drug delivery system like Rose and Nelson pump,Higuchi Leeper pump, Higuchi Theeuwes pump, Elementary osmotic pump etc. Various techniques available for preparation of OCDDS include push pull osmotic pump, Osmotic bursting osmotic pump, Liquid OROS,Telescopic capsule for delayed release, OROS-CT (colon targeting), and Sandwiched osmotic tablet system.These systems can be used for systemic as well as targeted delivery of drugs. Drug delivery from these systems,to a large extent, is independent of physiological f...
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Lecture Notes in Computer Science, 2003
This paper presents an improved method for detecting statistically significant shape differences ... more This paper presents an improved method for detecting statistically significant shape differences between image populations based on the multivariate Hotelling’s T2 test applied directly to image transformations. Performance of the method was evaluated using two phantom populations each consisting of 30 2D images with known average shape and known shape variability. Inverse-consistent linear-elastic image registration (ICLEIR) was used to construct a deformable template average image for both populations. The average image for the “normal” phantom population was used as the reference coordinate system to estimate ICLEIR correspondence transformations from the reference image to each population image. Following the work of Thirion et al., a multivariate two population Hotelling’s T2 test was performed on the displacement fields of these transformations at each voxel location in the reference coordinate system. We show that adding a conditioning constant ε to the singular values of the sample covariance matrices used in the Hotelling’s T2 test reduces the false-positive rate. Furthermore, it is shown that adjusting the value of ε focuses the statistical test response to the region of known shape differences present in the phantom image populations. Although limited, the phantom results presented in this paper provide baseline information for interpreting future results generated from real 3D medical images.
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2006 Conference on Computer Vision and Pattern Recognition Workshop (CVPRW'06), 2006
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Radiation Protection and Environment, 2013
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2009 IEEE International Symposium on Modeling, Analysis & Simulation of Computer and Telecommunication Systems, 2009
Managing client perceived pageview response time for multiple classes of service is essential in ... more Managing client perceived pageview response time for multiple classes of service is essential in today's highly competitive, e-commerce environment. We present Connection and Performance Model Driven Optimization (CP-MDO), a novel approach for providing optimal QoS as defined by a cost objective based on client perceived pageview response time and pageview drop rate. Our approach combines two vital models: (1) a
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2006 IEEE International Conference on Acoustics Speed and Signal Processing Proceedings, 2006
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Advances in Delivery Science and Technology, 2013
ABSTRACT The area of polymer–drug conjugates is expanding spectacularly in recent years. From mac... more ABSTRACT The area of polymer–drug conjugates is expanding spectacularly in recent years. From macromolecular prodrugs of established anticancer agents to novel targeted polymeric drug conjugate systems, their application has expanded exponentially. Delivery of new anticancer agents, combination therapies, treatment of diseases other than cancer, and novel polymer architectures are highly exciting and promising areas. It is hoped that in the next decade, some of these new approaches will reach clinical evaluation and few will see the light of marketing phase. The successful development of first-generation polymer–drug conjugates in the mid-1980s and 1990s has inspired more recent studies assessing their potential as drug delivery platforms for combination therapy. These early works unveiled unexpected therapeutic benefits but raised new issues, in particular in relation to “system design.” A better understanding of how drug combinations impact on cellular and molecular mechanisms is needed to rationally design new therapeutics. In nutshell it is to be believed that the interdisciplinary scientific approach to the applications of polymer–drug conjugate (PDC) will result in their translation into the clinic within this decade.
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Asian Pacific Journal of Tropical Biomedicine, 2012
... Sharma S, Lakshmi KS, Patidar A, Chaudhary A, Dhaker S. Studies on anti-inflammatory effect o... more ... Sharma S, Lakshmi KS, Patidar A, Chaudhary A, Dhaker S. Studies on anti-inflammatory effect of aqueous extract of leaves of Holoptelea integrifolia, Planch in rats. ... Srinivas RB, Kiran KKR, Naidu VG, Madhusudhana K, Agwane SB, Ramakrishna S, Diwan PV. ...
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Papers by P. Dinesh Kumar