Papers by Kimia Kahkeshan
Article history: Received on: 27/09/2012 Revised on: 14/10/2012 Accepted on: 24/10/2012 Available... more Article history: Received on: 27/09/2012 Revised on: 14/10/2012 Accepted on: 24/10/2012 Available online: 30/10/2012 The solubility behaviour of drugs remains one of the most exigent aspects in formulation development. These days, the number of new chemical entities has dramatically increased having hiccups of poor solubility and poor permeability. Solid dispersion as a dosage form has been established a superior option for the drugs having poor aqueous solubility. Solid dispersions in water-soluble carriers have engrossed considerable interest as a means of improving the dissolution rate and bioavailability of hydrophobic drugs. Although solid dispersions have tremendous potential for improving drug solubility and only a few marketed products using this approach. There are various methods available to improve the solubility of the new drug in which solid dispersion emerged promising. A Solid dispersion generally composed of two componentsthe drug and the polymer matrix. Numerous me...
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Papers by Kimia Kahkeshan