Papers by Evangelia Mourvaki
Reproductive Toxicology, 2009
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Metabolites
This study compared dietary isoflavone aglycones with the glycoside conjugates in a novel model o... more This study compared dietary isoflavone aglycones with the glycoside conjugates in a novel model of postmenopausal status, the aging domestic hen (Gallus gallus domesticus), to determine the effects on reproductive performance, cholesterol levels, and nutritional quality of eggs laid. Hens, 18 mo old, were randomized into four groups (n = 10/group) and fed for 28 d a conventional poultry corn/soymeal diet (Control), or diets supplemented with isoflavone glycosides from soy germ (diet A), isoflavone aglycons from a soy germ pasta (diet B), or conventional pasta lacking isoflavones (diet C). The egg-laying rate was recorded daily, plasma isoflavones and cholesterol were measured, and the nutritional composition of the eggs was determined. Egg-laying declined over a 4-week period in hens in the Control group and those fed isoflavone glycosides (diets A and C), whereas hens fed isoflavone aglycons (diet B) significantly increased their egg-laying efficiency. The total egg count and egg y...
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Italian Journal of Food Science, 2007
Forty rainbow trout (Oncorhynchus mykiss L.) reared in Valnerina (Umbria, Italy) were studied to ... more Forty rainbow trout (Oncorhynchus mykiss L.) reared in Valnerina (Umbria, Italy) were studied to determine the oxidative stability of fillets during a 5-day storage period at 2°C under continuous cool white fluorescent illumination. Chemical, physical and microbiological analyses were carried out. High quality fresh trout fillets were characterized by a low lipid and cholesterol content (4.2% and 37 mg/100 g, respectively), a high hypo-cholesterolemic/hyper-cholesterolemic fatty acid ratio (2.9) and low atherogenic and thrombogenic index values (0.45 and 0.21, respectively). After three days of display, the oxidative stability of the fillets decreased (2.7 vs 0.8 mg MDA/ kg, P<0.05) compromising the quality of the product. The lipid profile of the fillets also changed: the SFA and MUFA increased due to PUFA oxidation and/ or drip loss, while EPA and DHA tended to decrease. Nevertheless the levels of both long-chain PUFA were higher with respect to the baseline values, indicating ...
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Italian Journal of Food Science
ABSTRACT
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Thrombosis Research, 2013
I write on behalf of the corresponding Author and all authorship of the study published in Thromb... more I write on behalf of the corresponding Author and all authorship of the study published in Thrombosis Res. Vol. 16: pp 12-17 (2010). We recently noticed of wrong data of vitamin K2 forms reported in this study. The levels of the reported vitamin forms, namely Menaquinone-4, Menaquinone-5 and Menaquinone-7, and thus their sum as total vitamin K2, are one order of magnitude higher than the actual ones. The levels of vitamin K1 are correct, but the aforementioned wrong data on vitamin K2 also produced wrong values of the sum between vitamin K1 and K2. The mistake was the result of the incorrect transcription of laboratory data during the preparation of the manuscript. Unluckily, we fail to notice such an inaccuracy during the steps of manuscript revision and proofreading. Thewrong data are shown in: a) Table 3, b) Fig. 1B, and thus c) in the section “Results” of the text, Subsection 3.5. “Vitamin K”, in which the last two lines of the left column of page 15 read “... and a lower vitamin K2 level (7.40 ± 0.83 μg/l vs. 9.43 ± 1.27 μg/l) compared to...” need emendation. Correct data should read as follows:
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Thrombosis Research, 2010
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Thrombosis and Haemostasis, 2007
SummaryReview of literature has shown an increased rate of thrombotic complications in diabetic p... more SummaryReview of literature has shown an increased rate of thrombotic complications in diabetic patients with frequent episodes of hyperketonemia. However, the mechanisms by which ketosis promotes vascular disease in diabetic patients are unclear.It was the aim of this study to investigate early changes in haemostatic parameters and oxidative stress markers during the hyperketonemic status which follows the interruption of continuous subcutaneous insulin infusion (CSII) in type I diabetic patients. Eight CSII-treated type I diabetic patients underwent a 4-hour pump arrest. Blood glucose, insulin and 3-hydroxybutirate were measured to verify the metabolic response. A vein-occlusive (VO) test was performed for the determination of tPA and PAI-1 activities and their antigen levels before and after the CSII arrest. Coagulation factor VII and VIII were evaluated by one-stage PT and PTT method, respectively.TF, vWF, tPA and PAI-1 antigens were determined by ELISA, whereas tPA and PAI-1 ac...
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Theriogenology, 2012
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Theriogenology, 2010
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Reproductive Biology and Endocrinology, 2010
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Reproduction in Domestic Animals, 2007
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Pigment Cell Research, 2004
ABSTRACT We have synthesized an unsymmetrical salen-manganese complex to test its catalytic prope... more ABSTRACT We have synthesized an unsymmetrical salen-manganese complex to test its catalytic properties and possibly its application in controlling some aspects of oxidative stress in vitro and in vivo models. The ligand used in this study was a Schiff base obtained by condensing o-vanillin with 1,2 diamino propane. Manganese forms a symmetrical and stable coordinative bridge at the center of the complex and cannot be released. In the medium where it could display its toxic effects. This complex is a new low-molecular-weight compound that exhibits good Catalase and Superoxide Dismutase activities, destroying both superoxide and hydrogen peroxide. All described reactions are important for cell detoxification and in a variety of consequences such as aging, cancer diabetes and vitiligo. Clinical applications of cat-like molecules is a primary target because the natural enzyme cannot be used as a drug due to its instability in solution and to delivery problems. Therefore, we were prompted to synthesize a compound presenting definite characteristics to be used as mimic enzyme in vivo : (1) non-toxic at required concentrations, (2) active within the physiological pH range, (3) high stability constant, (4) its metabolism and fate can be monitored in vivo (to study dose-effect correlation) For this purpose we have set-up a simple and fast chromatographic method to monitor synthesis and degradation of these compounds. This method can be used without modification also to test light and thermal stability of preparations (i.e. vitiligo treatment) and to monitor metabolism and fate in humans.
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Meat Science, 2009
The effect of Outdoor or Indoor housing systems on the growth, welfare and carcass and meat quali... more The effect of Outdoor or Indoor housing systems on the growth, welfare and carcass and meat quality of a local rabbit population was investigated. The slaughter age was 103±2days. Open-field tests showed an effective capacity of the Outdoor group to combat stressors. Compared to Indoor rabbits, Outdoor rabbits showed better growth performance and higher slaughter weight (SW) (2535 vs 2137g; P&lt;0.01). Outdoor housing conditions increased the physical activity of rabbits and their hind legs were more developed (36.1% vs 34.9%; P&lt;0.01). Slaughter yield was lower in Outdoor rabbits (57.8% vs 58.4% SW; P&lt;0.05) due to the higher skin proportion (17.2% vs 15.6% SW; P&lt;0.05). Outdoor rabbit meat showed lower L∗ value (L. lumborum: 55.6 vs 59.2; P&lt;0.01; B. femoris: 53.0 vs 55.5; P&lt;0.01) and cooking loss (L. lumborum: 15.9% vs 18.1%; P&lt;0.05). Outdoor rabbit hind leg meat was characterized by lower water (74.5% vs 75.1%; P&lt;0.01) and higher protein (22.9% vs 22.6%; P&lt;0.01) and fat (1.4% vs 1.1%; P&lt;0.01) contents; lipids were lower in SFA and higher in MUFA. Outdoor rearing seems to be a possible alternative housing system that allays the ethical concerns of modern consumers while also providing good meat quality.
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Journal of Medicinal Food, 2005
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Papers by Evangelia Mourvaki