The model allows one to assess the non-linear penetrance of a genetic variant under different environmental stimuli, therefore help us to gain novel insights ...
Aug 1, 2011 · In this work, we propose to relax the linear G×E assumption and allow for non-linear G×E interaction under a varying coefficient model framework.
Feb 8, 2018 · The model allows us to examine how variants in a gene set are moderated by an environment factor to affect a disease phenotype.
A Nonlinear Model for Gene-Based Gene-Environment Interaction - PMC
www.ncbi.nlm.nih.gov › PMC4926416
Jun 4, 2016 · We proposed a gene-based nonlinear gene-environment interaction model. The model treats each gene as a unit to identify how an environmental ...
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This model is called the partial linear varying-coefficient model. The ... Varying coefficient model for gene- environment interaction: a non-linear look.
The model allows us to examine how variants in a gene set are moderated by an environment factor to affect a disease phenotype. We approached the problem from a ...
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The model allows one to assess the non-linear penetrance of a genetic variant under different environmental stimuli, therefore help us to gain novel insights ...
Additive varying-coefficient model for nonlinear gene-environment interactions. Authors. Cen Wu; Ping-Shou Zhong; Yuehua Cui. Abstract. Gene-environment (GxE) ...
Varying coefficient model for gene–environment interaction: a non-linear look. Bioinformatics, 2011. Variable Selection in Nonparametric Varying-Coefficient ...
The model allows us to examine how variants in a gene set are moderated by an environment factor to affect a disease phenotype. We approached the problem from a ...