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One of the main problems with such modelling frameworks is to determine the dynamics of gene regulatory networks (GRN). Recently, it has been observed in in ...
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Abstract. Modelling frameworks for biological networks are used to reason on the models and their properties. One of the main problems.
In this paper we propose to extend the modelling framework of R. Thomas in order to introduce such spatial information between genes, and we will show how these ...
In this paper we propose to extend the modelling framework of R. Thomas in order to introduce such spatial information between genes, and we will show how these ...
We present a core gene regulatory network for early cardiac development based on published temporal and spatial expression data of genes and their interactions.
Mar 10, 2020 · Boolean network models are one of the simplest models to study complex dynamic behavior in biological systems.
Gene regulatory networks (GRNs) provide a transformation function between the static genomic sequence and the primary spatial specification processes ...
Mar 1, 2019 · This review discusses the concept of gene regulation, describes the current state of the art in gene regulatory networks, including modeling and simulation,
In this work, we use Boolean networks, a methodology for modelling and simulating GRNs, to investigate the potential for doing this. Our results demonstrate ...
Oct 25, 2022 · We propose a new algorithm for fitting a Boolean network model to gene expression data that finds an optimal solution with respect to network structure and fit ...