May 4, 2016 · Figure 9: Influence of model resolution on the size of aggregates generated during a given simulation. Histograms show aggregate size vs.

The volume reduction caused by the loss in resolution allows more binding site accessibility, which can be quantified using a rule-based model with implicit ...

Influence of Model Resolution on Antibody. Aggregation Simulations. Kasra ... The geometric impacts of molecular aggregation have not been well studied ...

In this paper, we study the impact of model resolution on simulations of geometric structures using both our previously developed Monte Carlo simulation and a ...

The impact of model resolution on simulations of antibody aggregation is analyzed, focused on two antigens, a trivalent man-made antigen and a common shrimp ...

Oct 14, 2021 · Bibliographic details on Influence of model resolution on geometric simulations of antibody aggregation.

Here, we review the available computational toolbox to predict protein aggregation propensities, identify sequential or structural aggregation-prone regions.

Feb 26, 2024 · In this work, we develop an efficient strategy that can be used to investigate and gain insight into monoclonal antibody solutions under different conditions.

Missing: geometric | Show results with:geometric

Experimental studies have shown that the spatial organization of aggregated IgE-FcεRI complexes affect transmembrane signaling that initiate these responses.