Mar 29, 2006 · The most common approach is to identify genes encoding a specific metabolic enzyme by establishing sequence homology to functionally ...
Mar 29, 2006 · Using E. coli and S. cerevisiae metabolic networks, we illustrate predictive ability of each individual type of association evidence and show ...
Using E. coli and S. cerevisiae metabolic networks, we illustrate predictive ability of each individual type of association evidence and show that significantly ...
Identifying metabolic enzymes with multiple types of association evidence. Peter Kharchenko, Lifeng Chen, Yoav Freund, Dennis Vitkup, George Church.
Existing large-scale metabolic models of sequenced organisms commonly include enzymatic functions which can not be attributed to any gene in that organism.
Identifying metabolic enzymes with multiple types of association evidence ... association evidence is effective in predicting genes encoding metabolic enzymes.
This review focuses on the recent identification of RNA-binding activity of numerous metabolic enzymes.
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We illustrate that a combination of genome context and other functional association evidence is effective in predicting genes encoding metabolic enzymes. Our ...
Kharchenko et al. Identifying metabolic enzymes with multiple types of association evidence. BMC Bioinformatics. (2006). D. Lee et al. Predicting protein ...
Mar 29, 2011 · We report a sensitivity of 88% and specificity of 95% in identifying EC numbers and annotating enzymatic sequences from the E. coli genome which ...