Apr 1, 2018 · We propose a method for developing a spatio-temporal model of morphological differences in the brain due to normal aging.
Apr 1, 2018 · The spatio-temporal model can be used to compare an individual's brain morphology to a cognitively healthy reference population. Smooth ...
We developed a spatio-temporal model of morphological differences in the brain due to normal aging. The method provides a representative distribution of brain ...
Dec 5, 2017 · A spatio-temporal reference model of the aging brain. NeuroImage, 169,. 11-22. https://doi.org/10.1016/j.neuroimage.2017.10.040. Important ...
Huizinga, Wyke ; Poot, Dirk ; Vernooij, Meike et al. / A spatio-temporal reference model of the aging brain. In: Neuroimage. 2018 ; Vol. 169. pp. 11-22. ... A ...
The MCI concept was developed to identify the clinical parameters that define the earliest stages of the neurodegenerative process. The essence of the MCI ...
This paper presents a methodology for analysis of such 4D images, with brain aging as the primary application.
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Sep 18, 2022 · Here we perform spatiotemporal RNA-seq of mouse brain aging, encompassing 847 samples from 15 regions spanning 7 ages.
Jan 2, 2024 · In this study, we introduce a microstate analysis to capture whole-brain instantaneous phase distributions instead of pairwise differences.
Jul 19, 2024 · We develop the first machine learning models based on spatial transcriptomics ('spatial aging clocks') to reveal cell proximity effects during brain aging and ...