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Table 1
Association between plasma miR-224 level and clinicopathological characteristics in patients with HCC
| Variables | | n | Plasma miR-224 |
|---|
| Median | P valuea |
|---|
| Total | | 87 | 19.69 | |
| Gender | male | 59 | 17.02 | 0.1396 |
| female | 28 | 23.60 | |
| Age (years old) | < 70 | 32 | 17.23 | 0.3963 |
| 70 ≤ | 55 | 19.69 | |
| BMIb | < 25 | 60 | 20.27 | 0.1364 |
| 25 ≤ | 27 | 14.99 | |
| DMc | Positive | 25 | 17.22 | 0.2225 |
| Negative | 62 | 19.69 | |
| Viral infection (HBV or HCV) | Positive | 52 | 21.90 | 0.1207 |
| Negative | 35 | 16.82 | |
| Liver cirrhosis | Positive | 28 | 20.46 | 0.3848 |
| Negative | 59 | 17.32 | |
| Pathological Type | Welld | 23 | 16.82 | 0.3519 |
| Moderately or poorlye | 64 | 19.85 | |
| Vascular invasion | Positive | 14 | 16.90 | 0.4499 |
| Negative | 73 | 19.69 | |
| Tumor size (mm) | <20 | 35 | 14.99 | 0.0005 |
| 20 ≤ | 52 | 24.02 | |
| pStage (LCSGJf) | I | 30 | 15.36 | 0.0382 |
| II-IV | 57 | 20.34 | |
| pStage (TNM: AJCC/UICCg) | I | 62 | 19.85 | 0.4464 |
| II-IV | 25 | 17.16 | |
| Recurrence | Positive | 29 | 25.22 | 0.0027 |
| Negative | 58 | 16.21 | |