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Copyright © 2015 Chalah, Riachi, Ahdab, Créange, Lefaucheur and Ayache. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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Table 3
Studies supporting the role of deep gray matter substrates in multiple sclerosis fatigue.
Authors (Year) | Technique | Scales | Population | Outcome |
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Niepel et al., 2006 | MRI | FSS | 52 RRMS | Correlation of FSS with abnormal T1 relaxation time within the thalami |
Inglese et al., 2007 | MRI | MFI | 22 MS (11RRMS, 11 PPMS) | Correlation of MFI with the cerebral blood volume and flow in the thalamus and basal ganglia |
Téllez et al., 2008 | 1H-MRS | MFIS, FSS | 41 RRMS | Correlation of physical domain of MFIS with abnormal NAA/cr ratio within the lentiform nucleus |