Table 1

Clinical heterogeneity in affected members of family VSM-20

Patient	Sex	Onset (years)	Duration (years)	First Symptoms	Clinical syndrome(s) present
Patient	Sex	Onset (years)	Duration (years)	First Symptoms	Frontotemporal dementia	Amyotrophic lateral sclerosis	Parkinsonism	Other
I-2	F	57	3	Apathy, delusions	+	+		Delusions
II-3	M	35	2.5	Hand weakness		+
II-4	M	50	7	Poor judgement, apathy	+
II-7	F	46	9	Disoriented, bradyphrenia	+	+	+	Pseudobulbar affect
II-8	M	47	10	Poor judgement, dysexecutive	+
III-2	M	49	Alive	Apathy, depression	+		+
III-3	M	49	Alive	Apathy, poor judgement	+
III-7	F	39	3	Acalculia, Apraxia	+	+	+	Supranuclear gaze palsy
III-9	F	40	Alive	Leg weakness		+
III-15	M	41	Alive	Apathy dysexecutive	+		+