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| PMC full text: | Published online 2013 Dec 12. doi: 10.1155/2013/402592
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Table 2
Aerobic exercise and insulin resistance (randomized controlled trials).
| References | Gender | Age | Treatment | BW (kg) | BMI (kg/m2) | IS | Study Duration | Protocol | ΔBW (kg) | ΔBMI (kg/m2) | ΔIS (%) | IS Measure |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kelly et al. [51] | 9 boys 11 girls | 11.0 | Control exercise | 73.5 75.4 | 30.5 32.1 | 6.0 6.2 | 8 | 4 times/wk, 30–50 50–80% of VO2 peak | 0.8 1.1 | −0.1 0.0 | −2.8 5.2 | 2 (mmol/L) |
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| Meyer et al. [42] | 47 boys 49 girls | 12–16 | Control exercise | NA | 31.0 29.8 | 4.4 3.9 | 6 | 3 days/wk, 60–90 swimming, games, and so forth | NA | 0.3 −2.6* | 11.0 −20.8* | HOMA-IR |
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| Kim et al. [52] | 26 boys (Korean) | 17.0 | Control exercise | 90.4 89.7 | 29.4 29.6 | 2.9 2.5 | 6 | 5 days/wk, 40 Jump rope (60–90 jumps/min) | 0.0 −2.2* | −0.3 −1.0* | −18.2 −33.6* | HOMA-IR |
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| Savoye et al. [19] | 68 boys 106 girls | 8–16 | Control exercise | 91.2 87.0 | 36.2 35.8 | 5.2 5.1 | 1 | Exercise & behavior modification. >100 >200 65–80% of maximal HR | 6 5.0/7.7 −2.6†/0.3† | 6 1.1/1.6 −2.1†/−1.7† | 6 6.1/16.8 −27.7†/−27.8† | HOMA-IR |
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| Lee et al. [20] | 45 boys | 12–18 | Control exercise | 100.0 106.5 | 33.9 36.6 | 2.7 2.2 | 3 | 3 days/wk, 60 50~75% of VO2 peak | 2.6* −0.04 | 0.3 −0.3 | −3.7 18.2 | Euglycemic clamp (mL/kg/min per µU/min) |
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| Davis et al. [21] | 94 boys 128 girls | 7–11 | Control Low-dose exercise High-dose exercise | NA | 26.3 25.9 25.6 | 2.5 2.2 2.4 | 10–15 | 5 days/wk, HR > 150 Low-dose: 20 High-dose: 40 | NA | NA | Adjusted mean diff. 0.11 (high versus low) 0.56 (low versus con.) 0.67 (high versus con.) | Matsuda index of insulin sensitivity |
BMI: body mass index; BW: body weight; HOMA-IR: homeostasis model assessment of insulin resistance; IS: insulin sensitivity; OGTT: oral glucose tolerance test; Δ: Change score.
*Significantly different from baseline within each group (P < 0.05).
†Significantly different from controls or other groups (P < 0.05).