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== Function ==
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The [[cytochrome P450 oxidase|cytochrome P450]] proteins are monooxygenases that [[catalyze]] many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of [[prostaglandin H2|prostaglandin H<sub>2</sub>]] to [[thromboxane A2|thromboxane A<sub>2</sub>]], a potent [[vasoconstrictor]] and inducer of [[platelet aggregation]] and '''[[12-Hydroxyheptadecatrienoic acid]]''' (i.e. '''12-(''S'')-hydroxy-5''Z'',8''E'',10''E''-heptadecatrienoic acid''' or '''12-HHT''') and agonist of '''[[Leukotriene B4 receptor]]s''' (i.e. '''BLT2''' receptors)<ref>J Exp Med. 2008 Apr 14;205(4):759-66. doi: 10.1084/jem.20072329</ref> and mediator of certain BLT2 receptor]] actions<ref>J Biochem. 2015 Feb;157(2):65-71</ref>. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. The gene expresses two transcript variants.<ref name="entrez" />
==Inhibitors==
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