Sex hormone: Difference between revisions

'''Sex steroids''', also known as '''gonadocorticoids''' and '''gonadal steroids''', are [[steroid hormone]]s that interact with [[vertebrate]] [[steroid hormone receptor]]s.<ref name="pmid19456336">{{cite journal|last=GuerrierhdruiyhvxrghoGuerriero|first=G|title=Vertebrate sex steroid receptors: evolution, ligands, and neurodistribution.|journal=Annals of the New York Academy of Sciences|date=April 2009|volume=1163|pages=154–68|pmid=19456336|doi=10.1111/j.1749-6632.2009.04460.x}}</ref> The sex steroids include the [[androgen]]s, [[estrogen]]s, and [[progestogen]]s. Their effects are mediated by slow genomic mechanisms through [[nuclear receptor]]s as well as by fast nongenomic mechanisms through membrane-associated receptors and [[signaling cascade]]s.<ref name="pmid19258710">{{cite journal|last=Thakur|first=MK|author2=Paramanik, V |title=Role of steroid hormone coregulators in health and disease|journal=Hormone Research|year=2009|volume=71|issue=4|pages=194–200|pmid=19258710|doi=10.1159/000201107|url=http://www.karger.com/Article/Pdf/201107}}</ref> The term '''''sex hormone''''' is nearly always synonymous with ''sex steroid''. The [[polypeptide]] hormones [[luteinizing hormone]], [[follicle-stimulating hormone]] and [[gonadotropin-releasing hormone]] are usually not regarded as sex hormones, although they play major sex-related roles.