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}}</ref> However, it prevented the onset of ALD in two-thirds of the susceptible boys.<ref>{{Cite journal |last=Lerner |first=Barron H |date=March 2009 |title=Complicated lessons: Lorenzo Odone and medical miracles |url=https://linkinghub.elsevier.com/retrieve/pii/S0140673609605341 |journal=The Lancet |language=en |volume=373 |issue=9667 |pages=888–889 |doi=10.1016/S0140-6736(09)60534-1|pmid=19291841 |s2cid=38174463 }}</ref> The actual subject of the film, Lorenzo Odone, died of pneumonia in May 2008 at the age of 30, having lived two decades longer than originally predicted by doctors.<ref>{{cite news|title= Lorenzo loses battle for life but legacy of hope lives on|work= [[The Guardian]]|date=31 May 2008|publisher=Guardian News and Media Ltd|url= https://www.theguardian.com/science/2008/jun/01/medicalresearch.genetics|access-date=2012-10-11}}</ref>
[[Hugo Moser (scientist)|Hugo Moser]], on whom the character of Professor Nikolais was based, called the film's portrayal of him "an abomination".<ref name=MoserObit>{{cite news|title= Hugo Moser, 82; neurologist's portrayal in 'Lorenzo's Oil' belied his real character|work= [[Los Angeles Times]]|date=26 January 2007|url= https://
===Box office===
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