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;Intravenous iron therapy for non-anaemic, iron-deficient adults
Current evidence is limited to base any recommendations that intravenous iron therapy is beneficial for treating non-anaemic, iron-deficient adults.<ref>{{cite journal | vauthors = Miles LF, Litton E, Imberger G, Story D | title = Intravenous iron therapy for non-anaemic, iron-deficient adults | journal = The Cochrane Database of Systematic Reviews | volume = 12 | pages = CD013084 | date = December 2019 | pmid = 31860749 | pmc = 6924972 | doi = 10.1002/14651858.cd013084.pub2 }}</ref> Further research in this area is needed as current body of evidence is very low quality.
==Cancer Research==
The presence of ''[[Helicobacter pylori]]'' in the stomach can cause inflammation and can lower the threshold for the development of [[stomach cancer|gastric cancer]]. In the setting of iron deficiency, ''H. pylori'' causes more severe inflammation and the development of premalignant lesions<ref name = Noto2022>Noto JM, Piazuelo MB, Shah SC, Romero-Gallo J, Hart JL, Di C, Carmichael JD, Delgado AG, Halvorson AE, Greevy RA Jr, Wroblewski LE, Sharma A, Newton AB, Allaman MM, Wilson KT, Washington MK, Calcutt MW, Schey KL, Cummings BP, Flynn CR, Zackular JP, Peek RM Jr. Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori-induced inflammation-driven gastric carcinogenesis. J Clin Invest. 2022 Mar 22:e147822. doi: 10.1172/JCI147822. Epub ahead of print. PMID: 35316215</ref>. This inflammatory effect appears to be mediated, in part, through altered [[bile acid]] production including an increase in [[deoxycholic acid]], a secondary bile acid implicated in [[colorectal cancer|colon cancer]] and other [[gastrointestinal cancer]]s<ref name = Noto2022/>.
==See also==
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