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; Fungi
{{anchor|Rust of cassava}}
Several fungi bring about significant crop losses, one of the most serious being cassava root rot; the [[pathogen]]s involved are species of ''[[Phytophthora]]'', the genus which causes potato blight. Cassava root rot can result in losses of as much as 80 percent of the crop.<ref name="Alvarez 2012">{{cite book|last1=Alvarez |first1=Elizabeth |author2=Llano, Germán Alberto |author3=Mejía, Juan Fernando |chapter=Cassava diseases in Latin America, Africa and Asia |title=The Cassava Handbook |page=258 |year=2012 |url=https://www.academia.edu/download/98098352/The_Cassava_Handbook_2011.pdf#page=266}}<!--Scholar: cassava fungal diseases--></ref>
A major pest is a [[rust (fungus)|rust]] caused by ''Uromyces manihotis''.<ref name="Rust">{{cite web |url=https://www.cabi.org/isc/datasheet/55848 |title=''Uromyces manihotis'' (rust of cassava) |year=2019 |website=[[Invasive Species Compendium]] (ISC) |publisher=[[Centre for Agriculture and Bioscience International|CABI]] (Centre for Agriculture and Bioscience International) |access-date=27 October 2022 |archive-date=9 November 2022 |archive-url=https://web.archive.org/web/20221109225057/https://www.cabi.org/isc/datasheet/55848 |url-status=live }}</ref>
Superelongation disease, caused by ''[[Elsinoë brasiliensis]]'', can cause losses of over 80 percent of young cassava in Latin America when temperature and rainfall are high.<ref name="Alvarez 2012"/>
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