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==Personal==
==Personal==
===Early years and Education===
===Early years and Education===
Raghava was born in village Nagla Karan, Buland Shahr (UP), India in 1963. He did his B.Sc./M.Sc. from [http://www.nascollege.org/ N.A.S. College], Meerut, UP in 1982. His major subjects were Physics, Chemistry and Mathematics. He did his M.Sc in Physics with specialization in electronics from N.A.S. College, Meerut, UP in 1984. He did his M.Tech from [http://www.iitd.ac.in/ Indian Institute of Technology (I.I.T.), New Delhi] in 1986. In 1996 he received his Doctorate degree from Institute of Microbial Technology and Panjab University, Chandigarh in area of Bioinformatics. His PhD work focuses on "Computer Aided Prediction of Protein Conformation from Amino Acid Sequences of Biotechnological Relevance".
Raghava was born in village Nagla Karan, Buland Shahr (UP), India in 1963. He did his B.Sc./M.Sc. from [http://www.nascollege.org/ N.A.S. College], Meerut, UP in 1982. His major subjects were Physics, Chemistry and Mathematics. He did his M.Sc in Physics with specialization in electronics from N.A.S. College, Meerut, UP in 1984. He did his M.Tech from [http://www.iitd.ac.in/ Indian Institute of Technology (I.I.T.), New Delhi] in 1986. In 1996 he received his Doctorate degree from [http://www.imtech.res.in/ Institute of Microbial Technology] and Panjab University, Chandigarh in area of Bioinformatics. His PhD work focuses on "Computer Aided Prediction of Protein Conformation from Amino Acid Sequences of Biotechnological Relevance".


===Career and Higher Studies===
===Career and Higher Studies===

Revision as of 18:20, 30 January 2011

Dr. G. P. S. Raghava
Dr. G.P.S. Raghava
Born
NationalityIndian
Scientific career
FieldsBioinformatics
InstitutionsInstitute of Microbial Technology
Bioinformatics Center

Gajendra Pal Singh Raghava is a scientist and head of Bioinformatics center, Institute of Microbial Technology (IMTECH), Chandigarh, India (For detail visit his Home Page).

Personal

Early years and Education

Raghava was born in village Nagla Karan, Buland Shahr (UP), India in 1963. He did his B.Sc./M.Sc. from N.A.S. College, Meerut, UP in 1982. His major subjects were Physics, Chemistry and Mathematics. He did his M.Sc in Physics with specialization in electronics from N.A.S. College, Meerut, UP in 1984. He did his M.Tech from Indian Institute of Technology (I.I.T.), New Delhi in 1986. In 1996 he received his Doctorate degree from Institute of Microbial Technology and Panjab University, Chandigarh in area of Bioinformatics. His PhD work focuses on "Computer Aided Prediction of Protein Conformation from Amino Acid Sequences of Biotechnological Relevance".

Career and Higher Studies

He joined Institute of Microbial Technology, Chandigarh in 1986 as computer scientist. His primary duty was to develop/maintain computer software/hardware and IT infrastructure. He become head of bioinformatics center in 1994. He is also coordinator of distributed information centre (DIC) supported by DBT under BTISNET programme, where his primary duty is to built/maintain infrastructure required for protein modeling and engineering.

He worked as a Post Doctorate Fellow (PDF) at Oxford university as well as at European Bioinformatics Institute (EBI) Cambridge, United Kingdom for two years (1996–98). During this period he learned and developed number of web servers in area of computational biology particularly in Protein Modelling.

Achievements and Awards

File:Raghava award.png
Dr G P S Raghava receiving India Research Front Award 2009
File:Raghava pm2.png
Dr G P S Raghava receiving S. S. Bhatnagar Award from Prime Minister Dr Manmohan Singh
Dr G P S Raghava receiving National Bioscience Award from Science and Technology minister Shri Kapil Sibal

Distinguished Positions

Research interests

Accidentally in 1991, he got interest in research and developed a method for calculating concentration of Antibody/Antigen from ELISA data. In initial phase he developed computer programs for general biological problems. In later stage he developed prediction method for protein secondary structure prediction; his methods successfully compete in international competitions like casp. In 1999 he establish his research group at IMTECH with emphasis on proteins structure prediction and genome annotation. In 2001, his group also focussed on "Computer aided vaccine design" with emphasis on subunit vaccine design. Since 2006, his group is trying to integrate bioinformatics, chemoinformatics, pharmacoinformatics, clinical informatics in order to develop single plate form for designing drugs in insilico.

Web Services and Software

He believes in public domain software or open source software/documents. Thus his group is using free software and building infrastructure for bioinformatics. All software and web servers developed at his group are free for academic use. Recently his group have initiated a web portal Computational Resource for Drug Discovery (CRDD) under Open Source Drug Discovery . Services provided from his group can be broadly classified in following categories.

Computer-aided Protein Structure Prediction

Table I Computer-aided Protein Structure Prediction software
APSSP2 PROCLASS PSA RPFOLD BTEVAL BetatPred2 BetatPred CHpredict AR_NHPred
TBBPred BetaTurns BhairPred OXBench StruComp GammaPred AlphaPred PepStr SarPred

Immunoinformatics: Subunit Vaccine design

Table II Immunoinformatics software
PROPRED1 nHLApred MMBpred Pcleavage TAPpred CTLpred PROPRED
HLADR4pred MHC2pred MHC MHCbench AbAg BCEpred ABCpred
BCIPep HLApred MHCBN HaptenDB HLA_affi FDR4 Tmhcpred
CBtope NPtope

Genome Annotation

Table III Genome Annotation software
FTG GWBLAST GWFASTA EGPred SVMgene
SRF MyPattern GeneBench FTGPred CDpred
DNAbinder Polyapred Pprint ECGpred SGpred
PHDcleav siRNApred DesiRm MARSpred Iccaars

Functional Annotation of Proteins

Table IV Functional Annotation software
AC2Dgel NRpred GPCRpred GPCRsclass ESLpred PSLpred BTXpred Mitpred ESLpred2
SRTpred Oxypred VGIchan HSLpred DNAsize GSTpred Mango LGEpred CytoPred
NTXpred VICMpred AlgPred PseaPred RSL-Pred AntiBP COPid siRNAPred ISSPred
SubMitPred CyclinPred ChemoPred TBPred ProPrint plPred PseaPred2 ChloroPred SPred
PFMPred CancerPred

Chemoinformatics and Pharmacoinformatics

Table V Chemoinformatics and Pharmacoinformatics software
DADPRED DMKPred KiDoQ AntiBP AntiBP2 TOXIpred

Unclassified webservers and webpages

Table VI
Crag CRIP HIVbio BioTherapy GDPbio DrugPedia
LibNet Address RBpred Hplot Mafft SFEpred
OC Web Protanal Strucomp Sci. Writ Aasim BioSuite

Databases

List of Databases developed
MHCBN BCIPEP HaptenDB FSGP PRRDB HMRbase
AntigenDB PolysacDB OXDBase BIAdb SFdbase HIVsir

News from Group

New Servers announced from group
  • GenomeABC : A server for Benchmarking of Genome Assemblers.
  • DESTAMP: Designing of stable antibacterial peptides.
  • DRONA: Prediction of nucleic acids (DNA RNA) interacting residues in proteins

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