Abstract
Studying the epidemiology of fibromyalgia (FM) is very important to understand the impact of this disorder on persons, families and society. The recent modified 2010 classification criteria of the American College of Rheumatology (ACR), without the need of tender points palpation, allows that larger and nationwide surveys may be done, worldwide. This article reviews the prevalence and incidence studies done in the general population, in several countries/continents, the prevalence of FM in special groups/settings, the association of FM with some sociodemographic characteristics of the population, and the comorbidity of FM with others disorders, especially with headaches.
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Harstall C, Ospina M. How prevalent is chronic pain? Pain Clinical Updates [Internet]. 2003, 11:1–4. Available at http://www.iasp-pain.org/AM/AMTemplate.cfm?Section=Home&CONTENTID=7594&TEMPLATE=/CM/ContentDisplay.cfm&SECTION=Home. Accessed April 2013.
Azevedo L, Costa-Pereira A, Mendonça L, et al. Epidemiology of chronic pain: a population-based nationwide study on its prevalence, characteristics and associated disability in Portugal. J Pain. 2012;13:773–83.
Ablin J, Oren A, Cohen S, et al. Prevalence of fibromyalgia in the Israeli population: a population-based study to estimate the prevalence of fibromyalgia in the Israeli population using the London Fibromyalgia Epidemiology Study Screening Questionnaire (LFESSQ). Clin Exp Rheumatol. 2012;30 Suppl 74:39–43.
Neumann L, Buskila D. Epidemiology of fibromyalgia. Curr Pain Headache Rep. 2003;7:362–8.
White K, Harth M. Classification, epidemiology, and natural history of fibromyalgia. Curr Pain Headache Rep. 2001;5:320–9.
Wolfe F, Smythe HA, Yunus M, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Arthritis Rheum. 1990;33:160–72.
• Wolfe F, Clauw D, Fitzcharles M, et al. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res. 2010;62:600–10. A change in the concept of FM, excluding tender points sites palpation as an essential diagnostic criterion to make this diagnosis.
•• Wolfe F, Clauw D, Fitzcharles M, et al. Fibromyalgia criteria and severity scales for clinical and epidemiological studies: a modification of the ACR Preliminary Diagnostic Criteria for Fibromyalgia. J Rheumatol. 2011;38:1113–22. A revision of the 2010 diagnostic criteria, developing a survey questionnaire for epidemiological and clinical studies.
Guermazi M, Ghroubi S, Sellami M, et al. Fibromyalgia prevalence in Tunisia. Tunis Med. 2008;86:806–11.
Senna E, De Barros A, Silva E, et al. Prevalence of rheumatic diseases in Brazil: a study using the COPCORD approach. J Rheumatol. 2004;31:594–7.
White K, Speechley M, Harth M, Ostbye T. The London fibromyalgia epidemiology study: the prevalence of fibromyalgia syndrome in London, Ontario. J Rheumatol. 1999;26:1570–6.
McNally J, Matheson D, Bakowsky V. The epidemiology of self-reported fibromyalgia in Canada. Chronic Dis Can. 2006;27:9–16.
Wolfe F, Ross K, Anderson J, et al. The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum. 1995;38:19–28.
• Vincent A, Lahr B, Wolfe F, et al. Prevalence of fibromyalgia: a population-based study in Olmsted county, Minnesota, utilizing the Rochester epidemiology project. Arthritis Care Res. 2013;65:786–92. A recent epidemiological study, using the 2010 ACR diagnostic criteria for FM.
Haq S, Darmawan J, Islam M, et al. Prevalence of rheumatic diseases and associated outcomes in rural and urban communities in Bangladesh: a COPCORD study. J Rheumatol. 2005;32:348–53.
Scudds R, Li E, Scudds R. The prevalence of fibromyalgia syndrome in Chinese people in Hong Kong. J Musculoskelet Pain. 2006;14:3–11.
Veerapen K, Wigley R, Valkenburg H. Musculoskeletal pain in Malaysia: a COPCORD survey. J Rheumatol. 2007;34:207–13.
Farooqi A, Gibson T. Prevalence of the major rheumatic disorders in the adult population of north Pakistan. Rheumatology. 1998;37:491–5.
Prateepavanich P, Petcharapiruch S, Leartsakulpanitch J. Estimating the prevalence of fibromyalgia and its impacts on health in thais: a community-survey in Bangkok, Thailand [Abstract]. Value in Health. 2012;15:A678.
Prescott E, Kjøller M, Jacobsen S, et al. Fibromyalgia in the adult Danish population: I. A prevalence study. Scand J Rheumatol. 1993;22:233–7.
Bannwarth B, Blotman F, Roué-Le Lay K, et al. Fibromyalgia syndrome in the general population of France: a prevalence study. Joint Bone Spine. 2009;76:184–7.
• Perrot S, Vicaut E, Servant D, Ravaud P. Prevalence of fibromyalgia in France: a multi-step study research combining national screening and clinical confirmation: the DEFI study (Determination of Epidemiology of Fibromyalgia). BMC Musculoskelet Disord. 2011;12:224–32. A nationwide epidemiological study of FM in France.
Mäkelä M, Heliövaara M. Prevalence of primary fibromyalgia in the Finnish population. BMJ. 1991;303:216–9.
• Branco J, Bannwarth B, Failde I, et al. Prevalence of fibromyalgia: a survey in five European countries. Semin Arthritis Rheum. 2010;39:448–53. A large, nationwide epidemiological study of FM in France, Germany, Italy, Portugal, and Spain.
• Wolfe F, Brähler E, Hinz A, Häuser W. Fibromyalgia prevalence, somatic symptom reporting, and the dimensionality of polysymptomatic distress: results from a survey of the general population. Arthritis Care Res. 2013;65:777–85. A large, nationwide epidemiological study of FM in Germany, using the 2010 ACR diagnostic criteria for FM.
Andrianakos A, Trontzas P, Christoyannis F, et al. Prevalence of rheumatic diseases in Greece: a cross-sectional population based epidemiological study. The ESORDIG Study. J Rheumatol. 2003;30:1589–601.
Salaffi F, De Angelis R, Grassi W, et al. Prevalence of musculoskeletal conditions in an Italian population sample: results of a regional community-based study. I. The MAPPING study. Clin Exp Rheumatol. 2005;23:819–28.
Mas A, Carmona L, Valverde M, et al. Prevalence and impact of fibromyalgia on function and quality of life in individuals from the general population: results from a nationwide study in Spain. Clin Exp Rheumatol. 2008;2:519–26.
Lindell L, Bergman S, Petersson I, et al. Prevalence of fibromyalgia and chronic widespread pain. Scand J Prim Health Care. 2000;18:149–53.
Turhanoglu A, Yilmaz S, Kaya S, et al. The epidemiological aspects of fibromyalgia syndrome in adults living in turkey: a population based study. J Musculoskelet Pain. 2008;16:141–7.
Forseth K, Gran J. The prevalence of fibromyalgia among women aged 20–49 years in Arendal, Norway. Scand J Rheumatol. 1992;21:74–8.
Topbas M, Cakirbay H, Gulec H, et al. The prevalence of fibromyalgia in women aged 20–64 in Turkey. Scand J Rheumatol. 2005;34:140–4.
Clark P, Burgos-Vargas R, Medina-Palma C, et al. Prevalence of fibromyalgia in children: a clinical study of Mexican children. J Rheumatol. 1998;25:2009–14.
Barsante Santos A, Schulze Burti J, Lopes J, et al. Prevalence of fibromyalgia and chronic widespread pain in community-dwelling elderly subjects living in São Paulo, Brazil. Maturitas. 2010;67:251–5.
Kim C, Kim H, Kim J. Prevalence of chronic widespread pain and fibromyalgia syndrome: a Korean hospital-based study. Rheumatol Int. 2012;32:3435–42.
Gallinaro A, Feldman D, Natour J. An evaluation of the association between fibromyalgia and repetitive strain injuries in metalworkers of an industry in Guarulhos, Brazil. Joint Bone Spine. 2001;68:59–64.
Cobankara V, Unal U, Kaya A, et al. The prevalence of fibromyalgia among textile workers in the city of Denizli in Turkey. Int J Rheum Dis. 2011;14:390–4.
Toda K. The prevalence of fibromyalgia in Japanese workers. Scand J Rheumatol. 2007;36:140–4.
White K, Thompson J. Fibromyalgia syndrome in an Amish community: a controlled study to determine disease and symptom prevalence. J Rheumatol. 2003;30:1835–40.
Assumpção A, Cavalcante A, Capela C, et al. Prevalence of fibromyalgia in a low socioeconomic status population. BMC Musculoskelet Disord. 2009;10:64–70.
Sauer K, Kemper C, Glaeske G. Fibromyalgia syndrome: prevalence, pharmacological and non-pharmacological interventions in outpatient health care. An analysis of statutory health insurance data. Joint Bone Spine. 2011;78:80–4.
Forseth K, Gran J, Husby G. A population study of the incidence of fibromyalgia among women aged 26–55 yr. Rheumatology. 1997;36:1318–23.
Weir P, Harlan G, Nkoy F, et al. The incidence of fibromyalgia and its associated comorbidities: a population-based retrospective cohort study based on International Classification of Diseases, 9th Revision codes. J Clin Rheumatol. 2006;12:124–8.
Castells X, Coscolla R, Sunyol R, et al. “ESTUDI EPIFFAC” Impacto Familiar, Socio-Laboral y Económico de Padecer Fibromialgia. Available at www.universidadpacientes.org/dolor/docs/estudio_epiffac.pdf. Accessed April 2013
Haviland M, Banta J, Przekop P. Fibromyalgia: prevalence, course, and co-morbidities in hospitalized patients in the United States, 1999–2007. Clin Exp Rheumatol. 2011;29 Suppl 69:S79–87.
Wolfe F, Michaud K, Li T, Katz R. Chronic conditions and health problems in rheumatic diseases: comparisons with rheumatoid arthritis, noninflammatory rheumatic disorders, systemic lupus erythematosus, and fibromyalgia. J Rheumatol. 2010;37:305–15.
Schur E, Olarte M, Sullivan P, Buchwald D. Feeling bad in more ways than one: comorbidity patterns of medically unexplained and psychiatric conditions. J Gen Intern Med. 2007;22:818–21.
Peres M, Young W, Kaup A, et al. Fibromyalgia is common in patients with transformed migraine. Neurology. 2001;57:1326–8.
Ifergane G, Buskila D, Simiseshvely N, et al. Prevalence of fibromyalgia syndrome in migraine patients. Cephalalgia. 2006;26:451–6.
de Tommaso M, Sardaro M, Serpino C, et al. Fibromyalgia comorbidity in primary headaches. Cephalalgia. 2009;29:453–64.
• de Tommaso M, Federici A, Serpino C, et al. Clinical features of headache patients with fibromyalgia comorbidity. J Headache Pain. 2011;12:629–38. A large study about the association of some primary headaches with FM.
Tietjen G, Brandes J, Peterlin B, et al. Allodynia in migraine: association with comorbid pain conditions. Headache. 2009;49:1333–44.
Tietjen G, Herial N, Hardgrove J, et al. Migraine comorbidity constellations. Headache. 2007;47:857–65.
• Le H, Tfelt-Hansen P, Russell M, et al. Co-morbidity of migraine with somatic disease in a large population-based study. Cephalalgia. 2011;31:43–64. A large study of the migraine comorbidity, including FM, in twin cohort of Denmark.
Küçüksen S, Genç E, Yilmaz H, et al. The prevalence of fibromyalgia and its relation with headache characteristics in episodic migraine. Clin Rheumatol 2013 Feb 27, Epub ahead of print.
Aaron L, Burke M, Buchwald D. Overlapping conditions among patients with chronic fatigue syndrome, fibromyalgia, and temporomandibular disorder. Arch Intern Med. 2000;160:221–7.
Marcus D, Bernstein C, Rudy T. Fibromyalgia and headache: an epidemiological study supporting migraine as part of the fibromyalgia syndrome. Clin Rheumatol. 2005;24:595–601.
Ravindran M, Zheng Y, Timbol C, et al. Migraine headaches in chronic fatigue syndrome (CFS): comparison of two prospective cross-sectional studies. BMC Neurol. 2011;11:30–8.
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Dr. Luiz Paulo Queiroz reported no potential conflicts of interest relevant to this article.
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Queiroz, L.P. Worldwide Epidemiology of Fibromyalgia. Curr Pain Headache Rep 17, 356 (2013). https://doi.org/10.1007/s11916-013-0356-5
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DOI: https://doi.org/10.1007/s11916-013-0356-5