Abstract
BACKGROUND
Posttraumatic stress disorder (PTSD) is associated with medical and psychological morbidity. The prevalence of PTSD in urban primary care has not been well described.
OBJECTIVE
To measure the prevalence of PTSD in primary care patients overall and among those with selected conditions (chronic pain, depression, anxiety, heavy drinking, substance dependence (SD), irritable bowel syndrome (IBS), and immigrant status).
DESIGN
Cross-sectional study.
PARTICIPANTS
English-speaking patients aged 18–65 years old, awaiting primary care appointments in an urban academic medical center, were eligible for enrollment to determine PTSD prevalence (N = 509). Additional eligible participants (n = 98) with IBS or SD were subsequently enrolled.
MEASUREMENTS
PTSD (past year) and trauma exposure were measured with Composite International Diagnostic Interview. We calculated the prevalence of PTSD associated with depression, anxiety, heavy drinking, SD, IBS, and chronic pain. Only the analyses on heavy drinking, SD, and IBS used all 607 participants.
RESULTS
Among the 509 adults in primary care, 23% (95% CI, 19–26%) had PTSD, of whom 11% had it noted in the medical record. The prevalence of PTSD, adjusted for age, gender, race, and marital and socioeconomic statuses, was higher in participants with, compared to those without, the following conditions: chronic pain (23 vs 12%, p = .003), major depression (35 vs 11%, p < .0001), anxiety disorders (42 vs 14%, p < .0001), and IBS (34 vs 18%, p = .01) and lower in immigrants (13 vs 21%, p = .05).
CONCLUSIONS
The prevalence of PTSD in the urban primary care setting, and particularly among certain high-risk conditions, compels a critical examination of optimal approaches for screening, intervention, and referral to PTSD treatment.
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References
Yehuda R. Post-traumatic stress disorder. N Engl J Med. 2002;346(2):108–14 (Jan 10).
Goode E. A nation challenged: psychological trauma. The New York Times. September 18, 2001;B:1.
Mishra R. Mental toll on troops detailed. The Boston Globe. July 1, 2004:A1.
Hoge CW, Auchterlonie JL, Milliken CS. Mental health problems, use of mental health services, and attrition from military service after returning from deployment to Iraq or Afghanistan. JAMA. 2006;295(9):1023–32 (Mar 1).
Weisler RH, Barbee JG, Townsend MH. Mental health and recovery in the Gulf Coast after Hurricanes Katrina and Rita. JAMA. 2006;296(5):585–8.
Centers for Disease Control and Prevention. Health hazard evaluation of police officers and firefighters after Hurricane Katrina, New Orleans, Louisiana, October 17–28 and November 30–December 5, 2005: Centers for Disease Control and Prevention; 2006.
Lamberg L. Katrina survivors strive to reclaim their lives. JAMA. 2006;296(5):499–502.
American Psychiatric Association, ed. Diagnostic and Statistical Manual of Mental Disorders Fourth Edition. Washington, DC: American Psychiatric Association; 1994.
Mollica RF, Cardozo BL, Osofsky HJ, Raphael B, Ager A, Salama P. Mental health in complex emergencies. Lancet. 2004;364(9450):2058–67 (Dec 4–10).
Murray CJ, Lopez AD, eds. The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020. Cambridge, MA: Harvard University Press; 1996; No. 1.
Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62(6):593–602.
Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB. Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry. 1995;52:1048–60.
Breslau N, Kessler R, Chilcoat H, Schultz L, Davis G, Andreski P. Trauma and posttraumatic stress disorder in the community: The 1996 Detroit Area Survey of Trauma. Arch Gen Psychiatry. 1998; 55:626–32.
Stein M, McQuaid J, Pedrelli P, Lenox R, McCahill M. Posttraumatic stress disorder in the primary care medical setting. Gen Hosp Psychiatry. 2000;22:261–9.
Taubman-Ben-Ari O, Rabinowitz J, Feldman D, Vaturi R. Post-traumatic stress disorder in primary care settings: prevalence and physicians’ detection. Psychol Med. 2001;31:555–60.
Alim TN, Graves E, Mellman TA, Aigbogun N. Trauma exposure, posttraumatic stress disorder and depression in an African-American primary care population. J Natl Med Assoc. 2006;98(10):1630–6.
Magruder KM, Frueh BC, Knapp RG, et al. Prevalence of posttraumatic stress disorder in Veterans Affairs primary care clinics [see comment]. Gen Hosp Psychiatry. 2005;27(3):169–79.
Escalona R, Achilles G, Waitzkin H, Yager J. PTSD and somatization in women treated at a VA primary care clinic. Psychosomatics. 2004;45(4):291–6 (Jul–Aug).
Zlotnick C, Rodriguez BF, Weisberg RB, et al. Chronicity in posttraumatic stress disorder and predictors of the course of posttraumatic stress disorder among primary care patients. J Nerv Ment Dis. 2004;192(2):153–9 (Feb).
Weisberg RB, Bruce SE, Machan JT, Kessler RC, Culpepper L, Keller MB. Nonpsychiatric illness among primary care patients with trauma histories and posttraumatic stress disorder. Psychiatr Serv. 2002;53(7):848–54 (Jul).
Samson AY, Bensen S, Beck A, Price D, Nimmer C. Posttraumatic stress disorder in primary care. J Fam Pract. 1999;48(3):222–7.
Breslau N, Davis GC, Andreski P. Risk factors for PTSD-related traumatic events: a prospective analysis. Am J Psychiatry. 1995;152(4):529–35.
Edlund MJ, Unutzer J, Wells KB. Clinician screening and treatment of alcohol, drug, and mental problems in primary care: results from healthcare for communities. Med Care. 2004;42(12):1158–66 (Dec).
Walker EA, Katon W, Russo J, Ciechanowski P, Newman E, Wagner AW. Health care costs associated with posttraumatic stress disorder symptoms in women. Arch Gen Psychiatry. 2003;60(4):369–74.
Calhoun PS, Bosworth HB, Grambow SC, Dudley TK, Beckham JC. Medical service utilization by veterans seeking help for posttraumatic stress disorder. Am J Psychiatry. 2002;159(12):2081–6 (Dec).
Spertus IL, Yehuda R, Wong CM, Halligan S, Seremetis SV. Childhood emotional abuse and neglect as predictors of psychological and physical symptoms in women presenting to a primary care practice. Child Abuse Negl. 2003;27(11):1247–58 (Nov).
Andreski P, Chilcoat H, Breslau N. Post-traumatic stress disorder and somatization symptoms: a prospective study. Psychiatry Res. 1998;79(2):131–8 (Jun 15).
Asmundson GJ, Coons MJ, Taylor S, Katz J. PTSD and the experience of pain: research and clinical implications of shared vulnerability and mutual maintenance models. Can J Psychiatry. 2002;47(10):930–7.
Bryant RA, Marosszeky JE, Crooks J, Baguley IJ, Gurka JA. Interaction of posttraumatic stress disorder and chronic pain following traumatic brain injury. J Head Trauma Rehabil. 1999;14(6):588–94.
Otis JD, Keane TM, Kerns RD. An examination of the relationship between chronic pain and post-traumatic stress disorder. J Rehabil Res Dev. 2003;40(5):397–405.
Frayne SM, Seaver MR, Loveland S, et al. Burden of medical illness in women with depression and posttraumatic stress disorder. Arch Intern Med. 2004;164(12):1306–12.
Bonin MF, Norton GR, Asmundson GJ, Dicurzio S, Pidlubney S. Drinking away the hurt: the nature and prevalence of PTSD in substance abuse patients attending a community-based treatment program. J Behav Ther Exp Psychiatry. 2000;31(1):55–66 (Mar).
Rodriguez BF, Weisberg RB, Pagano ME, Machan JT, Culpepper L, Keller MB. Mental health treatment received by primary care patients with posttraumatic stress disorder. J Clin Psychiatry. 2003;64(10):1230–6.
Smith MV, Rosenheck RA, Cavaleri MA, Howell HB, Poschman K, Yonkers KA. Screening for and detection of depression, panic disorder, and PTSD in public-sector obstetric clinics. Psychiatr Serv. 2004;55(4):407–14 (Apr).
Hankin CS, Spiro A, 3rd, Miller DR, Kazis L. Mental disorders and mental health treatment among U.S. Department of Veterans Affairs outpatients: the Veterans Health Study. Am J Psychiatry. 1999;156(12):1924–30 (Dec).
Kubany ES, McKenzie WF, Owens JA, Leisen MB, Kaplan AS, Pavich E. PTSD among women survivors of domestic violence in Hawaii. Hawaii Med J. 1996;55(9):164–5 (Sep).
Davis TM, Wood PS. Substance abuse and sexual trauma in a female veteran population. J Subst Abuse Treat. 1999;16(2):123–7.
Najavits LM, Weiss RD, Shaw SR. The link between substance abuse and posttraumatic stress disorder in women. A research review. Am J Addict. 1997;6(4):273–83.
Reynolds M, Mezey G, Chapman M, Wheeler M, Drummond C, Baldacchino A. Co-morbid post-traumatic stress disorder in a substance misusing clinical population. Drug Alcohol Depend. 2005;77(3):251–8 (Mar 7).
Brown PJ, Recupero PR, Stout R. PTSD substance abuse comorbidity and treatment utilization. Addict Behav. 1995;20(2):251–4 (Mar–Apr).
Drossman DA, Leserman J, Nachman G, et al. Sexual and physical abuse in women with functional or organic gastrointestinal disorders. Ann Intern Med. 1990;113:828–33.
Drossman DA, Talley NJ, Leserman J, Olden KW, Barreiro MA. Sexual and physical abuse and gastrointestinal illness: review and recommendations. Ann Intern Med. 1995;123:782–94.
Holman EA, Silver RC, Waitzkin H. Traumatic life events in primary care patients: a study in an ethnically diverse sample. Arch Fam Med. 2000;9(9):802–10 (Sept/Oct).
Force UPST. Guide to Clinical Preventive Services, 2nd Edition. Bethesda, MD; 1996.
Spitzer RL, Kroenke K, Williams JB. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. JAMA. 1999;282(18):1737–44.
Drossman DA, Corazziari E, Talley NJ, Thompson WG, Whitehead WE. Rome II. The Functional Gastrointestinal Disorders. Diagnosis, Pathophysiology and Treatment: A Multinational Consensus. McLean, VA: Degnon Associates; 2000.
NIAAA. Helping Patients Who Drink Too Much: A Clinician’s Guide. http://pubs.niaaa.nih.gov/publications/Practitioner/CliniciansGuide2005/clinicians_guide.htm; 2006.
Purves AM, Penny KI, Munro C, et al. Defining chronic pain for epidemiological research assessing a subjective definition. Pain Clinic. 1998;10(3):139–47.
World Health Organization. Composite International Diagnostic Interview (CIDI): Version 2.1. Geneva: World Health Organization; 1997.
Kessler R, Andrews G, Mroczek D, Ustun B, Wittchen HU. The World Health Organization Composite International Diagnostic Interview Short-Form (CIDI-SF). Int J Methods Psychiatr Res. 1998;7(4):171–85.
Health, United States, 2004 With Chartbook on Trends in the Health of Americans. Hyattsville, MD: National Center for Health Statistics; 2004.
Dobie DJ, Kivlahan DR, Maynard C, Bush KR, Davis TM, Bradley KA. Posttraumatic stress disorder in female veterans: association with self-reported health problems and functional impairment. Arch Intern Med. 2004;164(4):394–400 (Feb 23).
Sherman JJ, Turk DC, Okifuji A. Prevalence and impact of posttraumatic stress disorder-like symptoms on patients with fibromyalgia syndrome. Clin J Pain. 2000;16(2):127–34 (Jun).
Engel CC, Jr., Liu X, McCarthy BD, Miller RF, Ursano R. Relationship of physical symptoms to posttraumatic stress disorder among veterans seeking care for gulf war-related health concerns. Psychosom Med. 2000;62(6):739–45 (Nov–Dec).
Asmundson GJ, Wright KD, Stein MB. Pain and PTSD symptoms in female veterans. Eur J Pain. 2004;8(4):345–50 (Aug).
Amir M, Kaplan Z, Neumann L, Sharabani R, Shani N, Buskila D. Posttraumatic stress disorder, tenderness and fibromyalgia. J Psychosom Res. 1997;42(6):607–13 (Jun).
Lauterbach D, Vora R, Rakow M. The relationship between posttraumatic stress disorder and self-reported health problems. Psychosom Med. 2005;67(6):939–47 (Nov–Dec).
Beckham J, Crawford A, Feldman ME, et al. Chronic posttraumatic stress disorder and chronic pain in Vietnam combat veterans. J Psychiatr Res. 1997;43(4):379–89.
Frayne SM, Skinner KM, Sullivan LM, et al. Medical profile of women Veterans Administration outpatients who report a history of sexual assault occurring while in the military. J Womens Health Gend Based Med. 1999;8(6):835–45 (Jul–Aug).
Liebschutz JM, Feinman G, Sullivan L, Stein MD, Samet J. Physical and sexual abuse in women infected with the human immunodeficiency virus: increased illness and health care utilization. Arch Intern Med. 2000;160:1659–64.
Liebschutz JM, Mulvey KP, Samet JH. Victimization among substance-abusing women: worse health outcomes. Arch Intern Med. 1997;157:1093–97.
Sharp TJ, Harvey AG. Chronic pain and posttraumatic stress disorder: mutual maintenance? Clin Psychol Rev. 2001;21(6):857–77 (Aug).
Griffin MG, Resick PA, Yehuda R. Enhanced cortisol suppression following dexamethasone administration in domestic violence survivors. Am J Psychiatry. 2005;162(6):1192–9 (Jun).
Nixon RD, Bryant RA, Moulds ML, Felmingham KL, Mastrodomenico JA. Physiological arousal and dissociation in acute trauma victims during trauma narratives. J Trauma Stress. 2005;18(2):107–13 (Apr).
Zlotnick C, Bruce SE, Weisberg RB, Shea MT, Machan JT, Keller MB. Social and health functioning in female primary care patients with post-traumatic stress disorder with and without comorbid substance abuse. Compr Psychiatry. 2003;44(3):177–83.
Jacobsen LK, Southwick SM, Kosten TR. Substance use disorders in patients with posttraumatic stress disorder: a review of the literature. Am J Psychiatry. 2001;158(8):1184–90.
Brady KT, Sinha R. Co-occurring mental and substance use disorders: the neurobiological effects of chronic stress. Am J Psychiatry. 2005;162(8):1483–93.
Bremner JD, Southwick SM, Darnell A, Charney DS. Chronic PTSD in Vietnam combat veterans: course of illness and substance abuse. Am J Psychiatry. 1996;153(3):369–75.
Bruce SE, Weisberg RB, Dolan RT, et al. Trauma and posttraumatic stress disorder in primary care patients. Prim Care Companion J Clin Psychiat. 2001;3(5):211–7 (Oct).
Kessler RC, Berglund P, Demler O, et al. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA. 2003;289(23):3095–105 (Jun 18).
Wang PS, Berglund P, Kessler RC. Recent care of common mental disorders in the United States: prevalence and conformance with evidence-based recommendations. J Gen Intern Med. 2000;15(5): 284–92.
Oquendo MA, Malone KM, Ellis SP, Sackeim HA, Mann JJ. Inadequacy of antidepressant treatment for patients with major depression who are at risk for suicidal behavior. Am J Psychiatry. 1999;156(2):190–4.
Seong-Yi B, Bowers B, Oakley L, Susman J. The recognition of depression: the primary care clinician’s perspective. Ann Fam Med. 2005;3:31–7.
Foa EB, Davidson JRT, Frances A. The expert consensus guideline series: treatment of post-traumatic stress disorder. J Clin Psychiatry. 1999;60(suppl 16):1–76.
Bradley R, Greene J, Russ E, Dutra L, Westen D. A multidimensional meta-analysis of psychotherapy for PTSD. Am J Psychiatry. 2005;162(2):214–27 (Feb).
Institute of Medicine, ed. Improving the Quality of Health Care for Mental and Substance Use Conditions: Quality Chasm Series. Washington, DC: The National Academies Press; 2006.
Katzelnick DJ, Simon GE, Pearson SD, et al. Randomized trial of a depression management program in high utilizers of medical care. Arch Fam Med. 2000;9(4):345–51 (Apr).
Lin EH, Katon W, Von Korff M, et al. Effect of improving depression care on pain and functional outcomes among older adults with arthritis: a randomized controlled trial. JAMA. 2003;290(18):2428–29 (Nov 12).
Simon GE, Katon W, Rutter C, et al. Impact of improved depression treatment in primary care on daily functioning and disability. Psychol Med. 1998;28(3):693–701 (May).
Von Korff M, Balderson BH, Saunders K, et al. A trial of an activating intervention for chronic back pain in primary care and physical therapy settings. Pain. 2005;113(3):323–30 (Feb).
Lin EH, VonKorff M, Russo J, et al. Can depression treatment in primary care reduce disability? A stepped care approach. Arch Fam Med. 2000;9(10):1052–8 (Nov–Dec).
Newbold KB. Self-rated health within the Canadian immigrant population: risk and the healthy immigrant effect. Soc Sci Med. 2005;60(6):1359–70.
Chen AW, Kazanjian A. Rate of mental health service utilization by Chinese immigrants in British Columbia. Can J Public Health. 2005;96(1):49–51.
Marshall GN, Schell TL, Elliott MN, Berthold SM, Chun CA. Mental health of Cambodian refugees 2 decades after resettlement in the United States. JAMA. 2005;294(5):571–9.
Dobie DJ, Maynard C, Kivlahan DR, et al. Posttraumatic stress disorder screening status is associated with increased VA medical and surgical utilization in women. J Gen Intern Med. 2006;21(suppl 3):S58–S64 (Mar).
Hemenway D, Prothrow-Stith D, Browne A. Report of the 2004 Boston Youth Survey. Boston: City of Boston; 2005 (Aug).
Ahern J, Galea S, Fernandez WG, Koci B, Waldman R, Vlahov D. Gender, social support, and posttraumatic stress in postwar Kosovo. J Nerv Ment Dis. 2004;192(11):762–70.
Glynn SM, Asarnow JR, Asarnow R, et al. The development of acute post-traumatic stress disorder after orofacial injury: a prospective study in a large urban hospital. J Oral Maxillofac Surg. 2003;61(7):785–92.
Muller RT, Goebel-Fabbri AE, Diamond T, Dinklage D. Social support and the relationship between family and community violence exposure and psychopathology among high risk adolescents. Child Abuse Negl. 2000;24(4):449–64.
Viinamaki H, Kontula O, Niskanen L, Koskela K. The association between economic and social factors and mental health in Finland. Acta Psychiatr Scand. 1995;92(3):208–13.
Steptoe A, Marmot M. Burden of psychosocial adversity and vulnerability in middle age: associations with biobehavioral risk factors and quality of life. Psychosom Med. 2003;65(6):1029–37.
Sherbourne CD, Stewart AL. The MOS social support survey. Soc Sci Med. 1991;32(6):705–14.
Miller DK, Malmstrom TK, Joshi S, Andresen EM, Morley JE, Wolinsky FD. Clinically relevant levels of depressive symptoms in community-dwelling middle-aged African Americans. J Am Geriatr Soc. 2004;52(5):741–8.
Matheson FI, Moineddin R, Dunn JR, Creatore MI, Gozdyra P, Glazier RH. Urban neighborhoods, chronic stress, gender and depression. Soc Sci Med. 2006;63(10):2604–16.
O’Toole TP, Arbelaez JJ, Lawrence RS; Baltimore Community Health Consortium. Medical debt and aggressive debt restitution practices: predatory billing among the urban poor. J Gen Intern Med. 2004;19(7):772–8.
Gaskin DJ, Hadley J. Population characteristics of markets of safety-net and non-safety-net hospitals. J Urban Health. 1999;76(3):351–70.
Bassuk EL, Buckner JC, Perloff JN, Bassuk SS. Prevalence of mental health and substance use disorders among homeless and low-income housed mothers. Am J Psychiatry. 1998;155(11):1561–4.
Acknowledgments
This work was supported by a Generalist Physician Faculty Scholar Award from the Robert Wood Johnson Foundation, Princeton, New Jersey (RWJF #045452) and by a career development award from the National Institute on Drug Abuse, National Institutes of Health (K23 DA016665).
We thank Jessica Geier, Minga Claggett-Borne, Lauren Kelly, Michael Rosas, Mary Reyes, Pavan Sekhar, Jen Tran, Eric Holder, and Mary Benitta Schickel for their aid in data collection, and Joann Elmore (MD MPH), Roger Weiss (MD), and Larry Culpepper (MD) for their comments on research design and analysis.
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Liebschutz, J., Saitz, R., Brower, V. et al. PTSD in Urban Primary Care: High Prevalence and Low Physician Recognition. J GEN INTERN MED 22, 719–726 (2007). https://doi.org/10.1007/s11606-007-0161-0
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DOI: https://doi.org/10.1007/s11606-007-0161-0