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Matrixgekoppelte Mikrofrakturierung

Ein neues Konzept zur Knorpeldefektbehandlung

Matrix-coupled microfracture

A new concept for cartilage defect repair

  • Leitthema
  • Published:
Arthroskopie Aims and scope

Zusammenfassung

Zur Behandlung lokaler Knorpeldefekte stehen unterschiedliche Verfahren zur Auswahl. Grundsätzlich werden Therapieansätze mit oder ohne Chondrozytentransplantation unterschieden. Die Behandlungen reichen von der Mikrofrakturierung über die Transplantation autogener osteochondraler Zylinder (OATS) bis hin zur autologen Chondrozytentransplantation (ACT). Das hier vorgestellte Verfahren der autologen matrixinduzierten Chondrogenese (AMIC) stellt eine neue Möglichkeit der Behandlung von chondralen Defekten dar. Hierbei wird das bewährte Verfahren der Mikrofrakturierung mit einem Implantat (Kollagenmatrix) und Fibrinkleber kombiniert. Die Kosten sind deutlich reduziert, und es ist eine einzeitige sofortige Behandlung von Knorpeldefekten möglich.

Abstract

There are different treatment options for cartilage defect repair. These consist of procedures with and without chondrocyte transplantation. Procedures include microfracturing, transplantation of osteochondral tissue (OATS), and autologous chondrocyte transplantation (ACT). A new technique for cartilage repair is the so-called autologous matrix-induced chondrogenesis (AMIC). This procedure is an innovative treatment combining the well-known microfracturing with collagen matrix implant and fibrin glue. The costs were significantly reduced, and immediate cartilage repair is possible in a single procedure.

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  1. Orthopädische Klinik, Campus Lübeck des Universitätsklinikums Schleswig-Holstein

    P. Behrens

  2. Orthopädische Klinik, Campus Lübeck des Universitätsklinikums Schleswig-Holstein, Ratzeburger Allee 160, 23538 , Lübeck

    P. Behrens

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  1. P. Behrens
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Correspondence to P. Behrens.

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Behrens, P. Matrixgekoppelte Mikrofrakturierung. Arthroskopie 18, 193–197 (2005). https://doi.org/10.1007/s00142-005-0316-0

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  • DOI: https://doi.org/10.1007/s00142-005-0316-0

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