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Peripherally Inserted Central Catheter-Related Infections in a Cohort of Hospitalized Adult Patients

  • Clinical Investigation
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Purpose

To determine the incidence and the risks factors of peripherally inserted central catheter (PICC)-related infectious complications.

Materials and Methods

Medical charts of every in-patient that underwent a PICC insertion in our hospital between January 2010 and October 2013 were reviewed. All PICC-related infections were recorded and categorized as catheter-related bloodstream infections (CR-BSI), exit-site infections, and septic thrombophlebitis.

Results

Nine hundred and twenty-three PICCs were placed in 644 unique patients, mostly male (68.3 %) with a median age of 58 years. 31 (3.4 %) PICC-related infections occurred during the study period corresponding to an infection rate of 1.64 per 1000 catheter-days. We observed 27 (87.1 %) CR-BSI, corresponding to a rate of 1.43 per 1000 catheter-days, 3 (9.7 %) septic thrombophlebitis, and 1 (3.2 %) exit-site infection. Multivariate logistic regression analysis showed a higher PICC-related infection rate with chemotherapy (odds ratio (OR) 7.2–confidence interval (CI) 95 % [1.77–29.5]), auto/allograft (OR 5.9–CI 95 % [1.2–29.2]), and anti-coagulant therapy (OR 2.2–95 % [1.4–12]).

Conclusion

Chemotherapy, auto/allograft, and anti-coagulant therapy are associated with an increased risk of developing PICC-related infections.

Clinical Advance

Chemotherapy, auto/allograft, and anti-coagulant therapy are important predictors of PICC-associated infections. A careful assessment of these risk factors may be important for future success in preventing PICC-related infections.

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Acknowledgments

All the authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article and state that this work has not received any funding.

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Authors and Affiliations

  1. Radiology Department, Percy Military Teaching Hospital, 101 avenue Henri Barbusse, 92140, Clamart, France

    Caroline Bouzad, François-Xavier Arnaud, Gabrielle Weber-Donat, Christophe Teriitehau, Jacques Baccialone & Julien Potet

  2. Military Centre for Epidemiology and Public Health (CESPA), GSBdD, 111 avenue de la Corse - Caserne Audéoud, 13007, Marseille-Aubagne, France

    Sandrine Duron

  3. Bacteriology Department, Begin Military Teaching Hospital, 69 avenue de Paris, 94160, Saint-Mandé, France

    Aurore Bousquet

  4. Radiology Department, Begin Military Teaching Hospital, 69 avenue de Paris, 94160, Saint-Mandé, France

    Laura Valbousquet

Authors
  1. Caroline Bouzad
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  2. Sandrine Duron
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  3. Aurore Bousquet
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  4. François-Xavier Arnaud
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  6. Gabrielle Weber-Donat
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  8. Jacques Baccialone
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Corresponding author

Correspondence to Caroline Bouzad.

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Conflict of interest

I, Dr. Caroline Bouzad, declare that I have no conflict of interest to disclose.

Ethical Approval

Institutional Review Board approval was obtained. This study is a retrospective one.

Informed Consent

For this type of study, formal consent is not required.

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Cite this article

Bouzad, C., Duron, S., Bousquet, A. et al. Peripherally Inserted Central Catheter-Related Infections in a Cohort of Hospitalized Adult Patients. Cardiovasc Intervent Radiol 39, 385–393 (2016). https://doi.org/10.1007/s00270-015-1182-4

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  • DOI: https://doi.org/10.1007/s00270-015-1182-4

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